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Dive into the research topics where Zhiqun Yu is active.

Publication


Featured researches published by Zhiqun Yu.


Journal of Flow Chemistry | 2017

A continuous-flow fischer indole synthesis of 3-methylindole in an ionic liquid

Jiangang Yu; Jianguo Xu; Zhiqun Yu; Yi Jin; Jie Li; Yanwen Lv

A continuous-flow reactor (Corning G1 reactor) was hereby introduced for Fischer indole synthesis of 3-methylindole by reaction of phenyl hydrazines and propylaldehyde. Stoichiometric Lewis acid, ZnCl2, was supplied as catalyst as well as remover of NH3 which generated during the indole ring formation. Ionic liquid ([EMIM][BF4]) was employed as solvent according to its high-temperature tolerance and good product distribution. After a straightforward extraction process, 3-methylindole could be obtained in a 95.3% yield (96.0% purity) under optimized conditions. Ionic liquid (IL) was then recovered by another extraction process, and the recovered IL acted nearly as efficiently as new IL for this Fischer indole reaction.


Organic Process Research & Development | 2012

A Continuous Kilogram-Scale Process for the Manufacture of o-Difluorobenzene

Zhiqun Yu; Yanwen Lv; Chuanming Yu


Organic Process Research & Development | 2013

A High-Output, Continuous Selective and Heterogeneous Nitration of p-Difluorobenzene

Zhiqun Yu; Yanwen Lv; Chuanming Yu; Weike Su


Tetrahedron Letters | 2013

Continuous flow reactor for Balz–Schiemann reaction: a new procedure for the preparation of aromatic fluorides

Zhiqun Yu; Yanwen Lv; Chuanming Yu; Weike Su


Organic Process Research & Development | 2015

Continuous-Flow Process for the Synthesis of 2-Ethylphenylhydrazine Hydrochloride

Zhiqun Yu; Gang Tong; Xiaoxuan Xie; Pengcheng Zhou; Yanwen Lv; Weike Su


Organic Process Research & Development | 2011

A Continuous Kilogram-Scale Process for the Manufacture of 7-Ethyltryptophol

Yanwen Lv; Zhiqun Yu; Weike Su


Organic Process Research & Development | 2016

Continuous-Flow Process for the Synthesis of m-Nitrothioanisole

Zhiqun Yu; Xiaoxuan Xie; Hei Dong; Jiming Liu; Weike Su


Chemical Engineering and Processing | 2017

A continuous flow microwave-assisted fischer indole synthesis of 7-Ethyltryptophol

Jianguo Xu; Jiangang Yu; Yi Jin; Jie Li; Zhiqun Yu; Yanwen Lv


Organic Process Research & Development | 2016

Continuous-Flow Process for Selective Mononitration of 1-Methyl-4-(methylsulfonyl)benzene

Zhiqun Yu; Pengcheng Zhou; Jiming Liu; Wenzuo Wang; Chuanming Yu; Weike Su


Organic Process Research & Development | 2017

A Fully Continuous-Flow Process for the Synthesis of p-Cresol: Impurity Analysis and Process Optimization

Zhiqun Yu; Xin Ye; Qilin Xu; Xiaoxuan Xie; Hei Dong; Weike Su

Collaboration


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Weike Su

Zhejiang University of Technology

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Yanwen Lv

Zhejiang University of Technology

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Chuanming Yu

Zhejiang University of Technology

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Guanghui Yang

Zhejiang University of Technology

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Guangjie Lu

Zhejiang University of Technology

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Jianyang Chen

Zhejiang University of Technology

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Shitian Xie

Zhejiang University of Technology

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Xinpeng Jiang

Zhejiang University of Technology

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