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A. Gigout

Merck KGaA

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Publication

Featured researches published by A. Gigout.

Osteoarthritis and Cartilage | 2017

Sprifermin (rhFGF18) enables proliferation of chondrocytes producing a hyaline cartilage matrix

A. Gigout; H. Guehring; D. Froemel; A. Meurer; C. Ladel; D. Reker; A.-C. Bay-Jensen; M.A. Karsdal; S. Lindemann

Osteoarthritis and Cartilage | 2018

Articular cartilage from osteoarthritis patients shows extracellular matrix remodeling over the course of treatment with Sprifermin (recombinanant human fibroblast growth factor 18)

D. Reker; C.S. Thudium; A. Sofie Siebuhr; T. Gantzel; C. Ladel; M. Michaelis; Morten A. Karsdal; A. Gigout; A.-C. Bay-Jensen

Journal of Translational Medicine | 2017

Sprifermin (rhFGF18) modulates extracellular matrix turnover in cartilage explants ex vivo

Ditte Reker; Cecilie Freja Kjelgaard-Petersen; Anne Sofie Siebuhr; Martin Michaelis; A. Gigout; Morten A. Karsdal; C. Ladel; Anne C. Bay-Jensen

Osteoarthritis and Cartilage | 2014

Enhanced integration with treatment of Sprifermin (rhfgf18) in a cartilage injury-repair model

George R. Dodge; A.J. Farran; R. Cocca; Gregory R. Meloni; B. Mohanraj; A. Gigout; Robert L. Mauck

Osteoarthritis and Cartilage | 2014

Sprifermin (rhfgf18) has an anabolic effect on human osteoarthritic chondrocytes involving fgfr3 and erk1/2 but not p38α and JNKS

A. Gigout; Sven Lindemann; Hans Guehring

Osteoarthritis and Cartilage | 2018

M1673 (GDF5 mutant) increases matrix production in primary porcine and human osteoarthritic chondrocytes

T. Mang; K. Kleinschmidt-Doerr; F. Ploeger; S. Lindemann; A. Gigout

Osteoarthritis and Cartilage | 2017

A strong correlation – influence of medium osmolarity on “chondrocyte health”

T. Mang; C. Arras; S. Lindemann; A. Gigout

Osteoarthritis and Cartilage | 2016

Effects of musculoskeletal related growth factors on cartilage extracellular matrix formation

Cecilie Freja Kjelgaard-Petersen; D. Reker; Natasja Stæhr Gudmann; A. Gigout; Anne Sofie Siebuhr; Morten A. Karsdal; M. Michealis; C. Ladel; A.-C. Bay-Jensen

Osteoarthritis and Cartilage | 2016

Establishment of a co-culture system to MIMIC OA progression without adding of cytokines

T. Mang; D. Werkmann; A.-C. Bay-Jensen; Anne Sofie Siebuhr; M.A. Karsdal; C. Ladel; A. Gigout; H. Guehring

Archive | 2016

FGF-18 EN TRASPLANTES DE INJERTOS Y PROCEDIMIENTOS DE INGENIERÍA DE TEJIDO

A. Gigout; Hans Guehring; C. Ladel

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Collaboration

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C. Ladel

Merck KGaA

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A.-C. Bay-Jensen

University of Southern Denmark

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S. Lindemann

Merck KGaA

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T. Mang

Merck KGaA

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Morten A. Karsdal

University of Southern Denmark

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Anne Sofie Siebuhr

AstraZeneca

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M.A. Karsdal

Novartis

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H. Guehring

Merck KGaA

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Cecilie Freja Kjelgaard-Petersen

Technical University of Denmark

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A.J. Farran

University of Pennsylvania

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