A. Somasekhar Reddy

CYCLOHEXENONE CARBOXYLATES. A VERSATILE SOURCE FOR FUSED ISOXAZOLES AND PYRAZOLES

The 6-carbethoxy-3,5-diarylcyclohex-2-enone (1) was subjected to condensation and 1,3-dipolar cycloaddition reactions to get fused isoxazole and pyrazole derivatives.

1,3-Dipolar Cycloaddition of Dipolar Reagents to Bifunctional Olefins with Chloramine-T --- Part-II

Abstract A one pot synthesis of pyrazoles and isoxazoles was achieved by 1,3-dipolar cycloaddition of nitrile imines and nitrile oxides to an activated olefins in the presence of chloramine-T.

1,4-PENTADIEN-3-ONES. A SOURCE FOR SELENANO 1,2,3- SELENA AND THIADIAZOLES

The 4-Selenanols (2,3) and 4-selenanones (4) were obtained by the reaction of 1,4-pentadien-3-ones (1) with sodium hydrogen selenide under different conditions. The fused 1,2,3-selenadiazoles (6) and 1,2,3-thiadiazoles (7) were prepared from 4 on oxidative cyclization with SeO2 and Hurd–Mori reaction with SOCl2.

Synthesis of Novel Spiro Tetrahydrothiapyrano-Isoxazolines and Pyrazolines

Abstract Cis 2,6-Diphenyltetrahydrothiapyranone (1) was subjected to Wittig reaction to generate exocyclic double bond (2a-c). Cycloaddition of nitrile oxides and nitrile imines to the latter led to a novel spiro tetrahydrothiapyranoisoxazolines (3a-f) and spiro tetrahydrothiapyranopyrazolines (4a-f)

Synthesis of Annelated 1,2,3-Selena- or -Thia-diazoles

The reaction of semicarbazones of 3,5-diphenylcyclohex-2-enone 2 and 3,5-diphenylcyclohexanone 8 with selenium dioxide and thionyl chloride resulted in annelated 1,2,3-selena- and thia-diazoles 3, 4, 5, 9 and 10.

Synthesis of some spiro piperidino-1,2,4-triazolidines and aziridines

The oxidative cyclization of the thiosemicarbazones of 4-piperidones (2) furnished spiro piperidino-1,2,4-triazoles (3,4,5), while the pyrolysis of 5 led to spiro piperidinoaziridines (6). The new compounds were characterized by IR and 1H NMR spectral data.© 1999 John Wiley & Sons, Inc. Heteroatom Chem 10: 313–317, 1999