D. Bhaskar Reddy

CYCLOHEXENONE CARBOXYLATES. A VERSATILE SOURCE FOR FUSED ISOXAZOLES AND PYRAZOLES

The 6-carbethoxy-3,5-diarylcyclohex-2-enone (1) was subjected to condensation and 1,3-dipolar cycloaddition reactions to get fused isoxazole and pyrazole derivatives.

AN EFFICIENT SYNTHESIS OF 6,8-DIARYLCARBAZOLES VIA FISCHER INDOLE CYCLIZATIONS

6,8Diaryl 6,7-dihydrocarba/.ole (4), 6,8diaryl 6,7,8,9, terahydrocarbazole (7), 6,8diary 1 carba/.olc (8) were obtaüied from the Fischer indole cyclization of 6 carbcthoxy3,5diarylcyclohex2-enI -one (1).

A simple strategy for styryl sulfonyl ethynylogues and 1,4-diarylbut-1-en-3-ynes

Abstract A general and simple strategy for 2-arylethenyl-2′-arylethynyl sulfones ( 9 ) and 1,4-diarylbut-1-en-3-ynes ( 10 ) has been developed by the lability of carbon-heteroatom bond in heterocycles, 1,2,3-selenadiazole ( 3 ) as the basis.

Thioglycolates in the Synthesis of Bis(styryl)-sulfones

Abstract E, Z-Bis (styryl) sulfones (6), have been prepared by the Knoevenagel condensation of Z-styryl-sulfonylacetic acid (5) with araldehydes. The compound 5 was prepared by a novel route using thioglycolates and phenylacetylene. The configuration of 6 has been assigned based on IR and 1H NMR spectral data.

1,3-Dipolar Cycloaddition of Dipolar Reagents to Bifunctional Olefins with Chloramine-T --- Part-II

Abstract A one pot synthesis of pyrazoles and isoxazoles was achieved by 1,3-dipolar cycloaddition of nitrile imines and nitrile oxides to an activated olefins in the presence of chloramine-T.

REGIOSPECIFIC AND REGIOSELECTIVE 1,3-DIPOLAR CYCLOADDITION OF DIPOLAR REAGENTS TO UNSYMMETRICAL BISOLEFINIC KETONES IN THE PRESENCE OF CHLORAMINE-T (CAT)

ABSTRACT The reaction of 1,5-diaryl-3-methyl-1,4-pentadien-3-one with araldehyde phenylhydrazone/araldoxime in the presence of chloramine-T proceeds regiospecifically in MeOH and regioselectively in AcOH leading to mono- and bis-pyrazolines/ isoxazolines.

SYNTHESIS AND CYCLOPROPANATION OF E,E AND Z,Z-1,3-BIS(STYRYLSULFONYL)BENZENE

Abstract The synthesis of 1,3-bis(styrylsulfonyl)benzene in two isomeric forms (Z. Z and E, E) and their cyclopropanation with dimethylsulfonium methylide has been described. The configurational assignments of these compounds have been made on the basis of IR, 1H NMR and 13C NMR spectral data.

REACTIVITY OF BIFUNCTIONAL ALKENES WITH DIAZOMETHANE

Abstract The cycloaddition of diazomethane to 1-aroyl-2-arylsulfonylethenes (1) and 1,2-bis (arylsulfonyl) ethenes (IV) under different conditions led to a variety of pyrazolines and pyrazoles. The reactivity of pyrazolines was also studied by pyrolysis, nitrosation and acylation.

1,3-Dipolar Cycloaddition of Dipolar Reagents to Bifunctional Bis Olefins in the Presence of Chloramine-T

The bifunctional bis pyrazolines and bis isoxazolines have been prepared from 1-aroyl-2-styrylsulfonylethenes and 1-arylsulfonyl-2-styrylsulfonylethenes.

SYNTHESIS AND SPECTRAL STUDIES OF SOME UNSATURATED SULPHONES

Abstract A new 5-chloro-2-methylbenzenesulphonylacetic acid has been prepared from 4-chlorotoluene. The condensation of this acid and 4-bromo, 4-methoxy, 3,4-dichloro and 4-chloro-3-methylbenzenesulphonyl-acetic acids with different araldehydes gave some new unsaturated sulphones. The trans-structure for these compounds has been arrived at on the basis of infrared and proton magnetic resonance spectral data.