Adem Doganer

Effects of traditional practices in the postpartum period on postpartum depression

ABSTRACT In this descriptive study, our aim was to assess the effects of traditional practices on postpartum depression. The participants were 461 Muslim mothers with infants aged between 2 weeks and 12 months, without a history of postpartum depression or other psychiatric problems and capable of communicating fluently. The participants were volunteers and were recruited from family health centers in urban Turkey between January 15 and April 15, 2015. Data were collected in a single face-to-face interview with each participant. Mothers in the research locality frequently have recourse to traditional practices in the postpartum period and the incidence of postpartum depression appears to be lower amongst those who use such practices.

The effect of electrolyte balance on the voice in hemodialysis patients

ObjectiveThe aim of the study was to demonstrate the effect of blood electrolytes on the voice in chronic hemodialysis patients.MethodsThe study included a total of 59 hemodialysis patients. Pre- and post-dialysis voice recordings were performed. In the analysis of vocal acoustic parameters, fundamental frequency (F0), jitter, shimmer, the noise-to-harmonics ratio (NHR), and F0 minimum and F0 maximum were measured. The Voice Handicap Index-10 (VHI-10), and maximum phonation time (MPT) were evaluated. For perceptual evaluation, the GRBAS scale was used. The duration of dialysis (years) and changes in weight during dialysis were recorded for each patient. From venous blood samples, measurements were taken of hemoglobin (Hb), albumin, Na+, K+, creatinine, uric acid, phosphorus, Ca++, and parathormone.ResultsThe difference in the pre and post-dialysis values of F0, shimmer, NHR and MPT were found to be statistically significant (p = 0.001). The only variable determined to have an effect on the change in F0 values was uric acid, and the change in the F0 values was statistically significant (p = 0.009). The only variable determined to have an effect on the change in shimmer values was sodium, and the change was statistically significant (p = 0.034). The only variable determined to have an effect on the change in NHR values was creatinine, and the change in the NHR values was statistically significant (p = 0.028). Hb and the duration of dialysis were determined to have a statistically significant effect on the change in MPT values (p = 0.001).ConclusionsThe results showed that uric acid was the agent creating a reduction in vocal cord vibration, the agent increasing the difference between vibration waves was Na+, and creatinine increased the NHR rate. The effect of these variables can be considered important in the understanding of vocal cord physiology.

Serum levels of GPER -1 in euthymic bipolar patients

Introduction Estrogen and its receptors have been suggested as playing a role in the pathogenesis of bipolar disorder (BD). Estrogen functions through the estrogen receptors alpha and beta and the recently discovered G-protein–coupled estrogen receptor-1 (GPER-1). The aim of this study was to evaluate serum GPER-1 levels in euthymic BD patients. Patients and methods The study population consisted of 38 euthymic outpatients meeting the criteria for BD in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition and 35 age- and gender-matched healthy controls. Medical histories were obtained and physical examinations and laboratory tests conducted. Results Serum GPER-1 levels were measured in both patients and controls and found to be significantly higher in the BD patients than in controls. These results were not influenced by the medications in use. Conclusion The results of this study demonstrated that GPER-1 may play a role in BD pathophysiology.

Effects of silica nanoparticles on isolated rat uterine smooth muscle

Abstract In spite of their widespread use, toxicity of silica nanoparticles (SiO2 NPs) to mammalian has not been extensively investigated. In the present study, it is aimed to investigate the effects and the mechanism of action of 20 nm sized SiO2 NPs on isolated uterine smooth muscle. A total number of 84 preparations of uterine strips were used in the experiments. Study was designed as four groups: group I (control), group II (0.2 mM SiO2 NPs), group III (0.4 mM SiO2 NPs) and group IV (0.8 mM SiO2 NPs). Spontaneous contractions were recorded using mechanical activity recording system. Superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) activities and malondialdehyde (MDA) levels were measured using the spectrophotometric methods. Apoptosis of the cells was detected using immunofluorescence staining assay. SiO2 NP distribution and ultrastructural changes were determined by transmission electron microscopy. In groups II–IV, the frequency of contraction was significantly lower than that of the group I, whereas the contraction energy significantly decreased only in group IV. SOD and GSH-Px activities were significantly lower in experimental groups compared to the control group. MDA level and apoptotic cells were significantly higher in all SiO2 groups compared to the control group. Numerous SiO2 NPs in cytoplasm and connective tissue were observed in all dose groups. These findings showed that 20 nm sized SiO2 NPs enter the connective tissue and cytoplasm of uterine muscle cells and cause oxidative stress and apoptosis leading to impaired uterine contractile activity.

A New Approach Using Hidden Markov Model and Bayesian Method for Estimate of Word Types in Text Mining

Determining thestructureofwords in the text for theoperationssuchasautomated information extractionandtextsummarizationofthetextisessential.Incomputers,textualanalysistodefine thetypeofthewordisconsideredasavitaladvantage.Definingthetypesofwordsprovidesan estimateofthesequenceofwordsinthesentence.Inthisarticle,estimatingtypesofTurkishwords isprovidedbydevelopingaHiddenMarkovModelandaBayesian-basednewmodel.Inthismodel, analgorithmisdevelopedwhichseparatesthesuffixesofthewordsandgroupingthewordsbycounts ofcharactersthatsuffixesofthewordsreceive.Atextcomposedof584Turkishwordsisusedfor thetestingthedependabilityofthemodel.Themodelhasachievedahighsuccessrateinpredicting thetypesofTurkishwords. KEyWoRdS Bayesian Methods, HMM, Modeling, Text Mining, Word Type

The Evaluation of Hematologic and Platelet Function in Total Septum Reconstruction Patients

Objective: Nasal septal deviation is a common disorder of the nose and patients commonly visit clinics with complaints of nasal obstruction. As a result of nasal obstruction, patients are exposed to snoring, which causes hypoxia.