Saime Sagiroglu

The effect of electrolyte balance on the voice in hemodialysis patients

ObjectiveThe aim of the study was to demonstrate the effect of blood electrolytes on the voice in chronic hemodialysis patients.MethodsThe study included a total of 59 hemodialysis patients. Pre- and post-dialysis voice recordings were performed. In the analysis of vocal acoustic parameters, fundamental frequency (F0), jitter, shimmer, the noise-to-harmonics ratio (NHR), and F0 minimum and F0 maximum were measured. The Voice Handicap Index-10 (VHI-10), and maximum phonation time (MPT) were evaluated. For perceptual evaluation, the GRBAS scale was used. The duration of dialysis (years) and changes in weight during dialysis were recorded for each patient. From venous blood samples, measurements were taken of hemoglobin (Hb), albumin, Na+, K+, creatinine, uric acid, phosphorus, Ca++, and parathormone.ResultsThe difference in the pre and post-dialysis values of F0, shimmer, NHR and MPT were found to be statistically significant (p = 0.001). The only variable determined to have an effect on the change in F0 values was uric acid, and the change in the F0 values was statistically significant (p = 0.009). The only variable determined to have an effect on the change in shimmer values was sodium, and the change was statistically significant (p = 0.034). The only variable determined to have an effect on the change in NHR values was creatinine, and the change in the NHR values was statistically significant (p = 0.028). Hb and the duration of dialysis were determined to have a statistically significant effect on the change in MPT values (p = 0.001).ConclusionsThe results showed that uric acid was the agent creating a reduction in vocal cord vibration, the agent increasing the difference between vibration waves was Na+, and creatinine increased the NHR rate. The effect of these variables can be considered important in the understanding of vocal cord physiology.

Clinical and Histopathological Findings of Chordomas: a Case Report

Abstract Chordomas are rare malignant tumors that develop from the residual of embryonic notochord. These tumors may be seen along the spine and have a local aggressive progression. Skull base chordomas often originate from the clivus as localization. These tumors are usually found to be overgrown when they are diagnosed. They are locally invasive and rarely develop distant metastasis. These chordomas cannot usually be completely removed due to their localization. Because these tumors are advanced at the time of diagnosis and are adjacent to important structures, they are among the tumors with high rates of mortality and morbidity. Surgery and/or radiotherapy is administered for the treatment.

An objective evaluation of the laryngeal roof

Aim: The anatomic measurements of the thyroid cartilage, which is an important part of the laryngeal roof, were calculated using computed tomography (CT) and the data obtained were compared in two groups of male and female. Material and Methods: A total of 148 adult patients were examined in this retrospective, cross-sectional study. All the patients were aged over18 year and presented to emergency ward between 2015 and 2016 due to trauma. Cervical vertebra CT was taken and the reformatted two-dimensional images were examined. Measurements were taken on the images at two separate levels of the interlaminar angle (ILA), thyroid prominence angle and the distance of the vocal cords from the lower edge of the thyroid. Results: The ILA in the glottis region was measured as 74.02°±17.23° for males and as 98.00°±12.78° for females. The difference between the genders was statistically significant (p<0.001). The distance of the vocal cords from the lower edge of the thyroid cartilage was measured as 7.12 ±2.29mm for males and 5.15±2.06mm for females. Conclusion: The results of the ILA measurements in this study were observed to be narrower in both genders than the measurements given in classic reference books. The ILA in both the regionsof glottis and supraglottiswas measured as a narrower angle in males than in females. These results show the presence of sexual dimorphism in the Kahramanmaraş region where the study was conducted.

The Evaluation of Hematologic and Platelet Function in Total Septum Reconstruction Patients

Objective: Nasal septal deviation is a common disorder of the nose and patients commonly visit clinics with complaints of nasal obstruction. As a result of nasal obstruction, patients are exposed to snoring, which causes hypoxia.