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Featured researches published by Amalia Laborde.


Environmental Health Perspectives | 2014

Children's health in Latin America: the influence of environmental exposures

Amalia Laborde; Fernando Tomasina; Fabrizio Bianchi; Marie Noel Brune; Irena Buka; Pietro Comba; Lilian Corra; Liliana Cori; Christin Maria Duffert; Raul Harari; Ivano Iavarone; Melissa A. McDiarmid; Kimberly A. Gray; Peter D. Sly; Agnes Soares; William A. Suk; Philip J. Landrigan

Background Chronic diseases are increasing among children in Latin America. Objective and Methods To examine environmental risk factors for chronic disease in Latin American children and to develop a strategic initiative for control of these exposures, the World Health Organization (WHO) including the Pan American Health Organization (PAHO), the Collegium Ramazzini, and Latin American scientists reviewed regional and relevant global data. Results Industrial development and urbanization are proceeding rapidly in Latin America, and environmental pollution has become widespread. Environmental threats to children’s health include traditional hazards such as indoor air pollution and drinking-water contamination; the newer hazards of urban air pollution; toxic chemicals such as lead, asbestos, mercury, arsenic, and pesticides; hazardous and electronic waste; and climate change. The mix of traditional and modern hazards varies greatly across and within countries reflecting industrialization, urbanization, and socioeconomic forces. Conclusions To control environmental threats to children’s health in Latin America, WHO, including PAHO, will focus on the most highly prevalent and serious hazards—indoor and outdoor air pollution, water pollution, and toxic chemicals. Strategies for controlling these hazards include developing tracking data on regional trends in children’s environmental health (CEH), building a network of Collaborating Centres, promoting biomedical research in CEH, building regional capacity, supporting development of evidence-based prevention policies, studying the economic costs of chronic diseases in children, and developing platforms for dialogue with relevant stakeholders. Citation Laborde A, Tomasina F, Bianchi F, Bruné MN, Buka I, Comba P, Corra L, Cori L, Duffert CM, Harari R, Iavarone I, McDiarmid MA, Gray KA, Sly PD, Soares A, Suk WA, Landrigan PJ. 2015. Children’s health in Latin America: the influence of environmental exposures. Environ Health Perspect 123:201–209; http://dx.doi.org/10.1289/ehp.1408292


Annals of global health | 2016

E-Waste Informal Recycling: An Emerging Source of Lead Exposure in South America

Antonio Pascale; Adriana Sosa; Cristina B. Bares; Alejandra Battocletti; María José Moll; Darío Pose; Amalia Laborde; Hugo González; Gabriella Feola

BACKGROUND Primitive electronic waste (e-waste) recycling creates exposures to several hazardous substances including lead. In Uruguay, primitive recycling procedures are a significant source of lead exposure. OBJECTIVES The aim of this study was to examine lead exposure in blood lead levels (BLLs) in low-income children exposed to lead through burning cables. METHODS A sample of children and adolescents exposed to lead through burning cable activities were assessed at the Department of Toxicology in Montevideo, Uruguay, between 2010 and 2014. Soil lead levels of residences were taken shortly after their assessment. FINDINGS The final sample included 69 children and adolescents (mean age 7.89 years). More than 66% of participants had an additional source of lead exposure—manual gathering of metals—and <5% were exposed to lead through landfills or paint. Average BLLs at first consultation were 9.19 ug/dL and lower at the second measurement (5.86 μg/dL). Data from soil lead levels ranged from 650 to 19,000 mg of lead/kg of soil. The interventions conducted after the assessment included family education in the clinic and at home, indoor and outdoor remediation. We found a decrease in BLLs of 6.96 μg/dL. Older children had lower BLLs (r = −0.24; P =0.05). Statistical analyses also showed that children living in areas with higher soil lead levels had significantly higher BLLs (r = 0.50; P < 0.01). Additionally, we found greater BLLs from burning cable activities when children had been exposed to lead-based paint (r = 0.23; P < 0.1). CONCLUSION Among children exposed to e-waste recycling, the most common additional source of lead exposure was the manual gathering of metals. The average BLL among children and adolescents in this study is higher than the BLLs currently suggested in medical intervention. Future research should focus on exploring effective interventions to reduce lead exposure among this vulnerable group.


Revista Cubana de Salud Pública | 2010

Vigilancia de la exposición a radiaciones ionizantes en el personal universitario de la salud

Fernando Tomasina; Amalia Laborde; Freddy Spontón; Daniel Blanco; Carlos Pintado; Nurit Stolovas; Nancy Satragno

Introduccion El programa de vigilancia de exposicion a radiaciones ionizantes en el ambiente laboral involucra las dosimetrias personales de los trabajadores y su evaluacion comparativa con los valores de referencia, lo que permite priorizar, y por lo tanto, tomar acciones de prevencion eficaces. Objetivos Presentar los resultados del programa de vigilancia en salud ocupacional de los trabajadores universitarios expuestos a radiaciones ionizantes durante el periodo 2003-2006. Metodos Estudio descriptivo retrospectivo longitudinal. Los datos dosimetricos fueron obtenidos de fuentes secundarias, a partir de la base de datos del programa de vigilancia dosimetrica de la Universidad de la Republica. La valoracion de la exposicion se realizo mediante dosimetria de film. Se analizaron los registros de los valores dosimetricos personales en el marco del programa de vigilancia, de los anos 2003, 2004, 2005 y 2006. Resultados Se observaron valores dosimetricos que no superaron los valores de referencia admitidos como maximos anuales. La dosis anual maxima recibida fue de 15,72 milisieverts, correspondiente a las areas de diagnostico y tratamiento especializado del Hospital Universitario. Conclusiones La vigilancia de la exposicion ha permitido orientar el control medico periodico especifico asi como extremar acciones de radioproteccion. En este sentido, el departamento de Salud Ocupacional esta realizando tareas de educacion y difusion del programa para reforzar las medidas de prevencion.


The Lancet Global Health | 2014

Networking to advance progress in children's environmental health

Peter D. Sly; Maria Neira; Gwen W. Collman; David O. Carpenter; Philip J. Landrigan; Martin van den Berg; Fernando Diaz Barriga; Mathuros Ruchirawat; Amalia Laborde; Antonio Pascale; Michelle Heacock; Marguerite T Dalmau; William A. Suk


Adicciones | 2010

Pasta base de cocaína: experiencia del Centro de Información y Asesoramiento Toxicológico

Antonio Pascale; Alba Negrín; Amalia Laborde


Workshop on Advances in the Use of Biomarkers in Children | 2006

Evaluación clínica y biomarcadores de genotoxicidad en una población de niños y adultos expuestos a múltiples plaguicidas

Amalia Laborde; Liria Martínez; Wilner Martínez López; Leticia Méndez Acuña; María José Morador; Teresita Fuster; Freddy Spontón; Fernando Tomasina


Revista Médica del Uruguay | 2006

Estudio epidemiológico de una población expuesta laboralmente a plomo

Amalia Laborde; Stella de Ben; Fernando Tomasina; Raquel González-San Martín; María Noel Tortorella; Fredtdy Sponton


Clinical Therapeutics | 2017

Epidemiological Profile of Antidepressant Agents Poisonings In Uruguay: Received Consults at The National Poisoning Information Centre During 2010–2012

C. Amigó; M. Tortorella; Viviana Domínguez; Noelia Speranza; Amalia Laborde; Gustavo Tamosiunas


Annals of global health | 2016

Reducing blood lead levels in children exposed to electronic waste recycling in Montevideo

Russell Dowling; G. Feola; Amalia Laborde; S. Gualtero; L. Hernandez


Revista Médica del Uruguay | 2015

Perfil epidemiológico de las intoxicaciones por benzodiazepinas recibidas en el Centro de Información y Asesoramiento Toxicológico uruguayo en el período 2010-2011

Viviana Domínguez Trobo; María Noel Tortorella; Noelia Speranza; Carolina Amigo; Amalia Laborde; Alejandro Goyret; Gustavo Tamosiunas

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Fernando Tomasina

University of the Republic

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Antonio Pascale

University of the Republic

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Freddy Spontón

University of the Republic

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Noelia Speranza

University of the Republic

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C. Amigó

University of the Republic

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M. Tortorella

University of the Republic

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Cristina B. Bares

Virginia Commonwealth University

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Philip J. Landrigan

Icahn School of Medicine at Mount Sinai

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William A. Suk

National Institutes of Health

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