Amanda W. Rowe

The 2013 International Society for Heart and Lung Transplantation Guidelines for mechanical circulatory support: Executive summary

Institutional Affiliations Co-chairs Feldman D: Minneapolis Heart Institute, Minneapolis, Minnesota, Georgia Institute of Technology and Morehouse School of Medicine; Pamboukian SV: University of Alabama at Birmingham, Birmingham, Alabama; Teuteberg JJ: University of Pittsburgh, Pittsburgh, Pennsylvania Task force chairs Birks E: University of Louisville, Louisville, Kentucky; Lietz K: Loyola University, Chicago, Maywood, Illinois; Moore SA: Massachusetts General Hospital, Boston, Massachusetts; Morgan JA: Henry Ford Hospital, Detroit, Michigan Contributing writers Arabia F: Mayo Clinic Arizona, Phoenix, Arizona; Bauman ME: University of Alberta, Alberta, Canada; Buchholz HW: University of Alberta, Stollery Children’s Hospital and Mazankowski Alberta Heart Institute, Edmonton, Alberta, Canada; Deng M: University of California at Los Angeles, Los Angeles, California; Dickstein ML: Columbia University, New York, New York; El-Banayosy A: Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania; Elliot T: Inova Fairfax, Falls Church, Virginia; Goldstein DJ: Montefiore Medical Center, New York, New York; Grady KL: Northwestern University, Chicago, Illinois; Jones K: Alfred Hospital, Melbourne, Australia; Hryniewicz K: Minneapolis Heart Institute, Minneapolis, Minnesota; John R: University of Minnesota, Minneapolis, Minnesota; Kaan A: St. Paul’s Hospital, Vancouver, British Columbia, Canada; Kusne S: Mayo Clinic Arizona, Phoenix, Arizona; Loebe M: Methodist Hospital, Houston, Texas; Massicotte P: University of Alberta, Stollery Children’s Hospital, Edmonton, Alberta, Canada; Moazami N: Minneapolis Heart Institute, Minneapolis, Minnesota; Mohacsi P: University Hospital, Bern, Switzerland; Mooney M: Sentara Norfolk, Virginia Beach, Virginia; Nelson T: Mayo Clinic Arizona, Phoenix, Arizona; Pagani F: University of Michigan, Ann Arbor, Michigan; Perry W: Integris Baptist Health Care, Oklahoma City, Oklahoma; Potapov EV: Deutsches Herzzentrum Berlin, Berlin, Germany; Rame JE: University of Pennsylvania, Philadelphia, Pennsylvania; Russell SD: Johns Hopkins, Baltimore, Maryland; Sorensen EN: University of Maryland, Baltimore, Maryland; Sun B: Minneapolis Heart Institute, Minneapolis, Minnesota; Strueber M: Hannover Medical School, Hanover, Germany Independent reviewers Mangi AA: Yale University School of Medicine, New Haven, Connecticut; Petty MG: University of Minnesota Medical Center, Fairview, Minneapolis, Minnesota; Rogers J: Duke University Medical Center, Durham, North Carolina

Mechanical circulatory support device database of the international society for heart and lung transplantation: first annual report—2003

Over the last 2 decades, mechanical circulatory support devices have been developed with the goal of supporting patients with advanced heart failure as a bridge to cardiac transplantation, a bridge to recovery, and an alternative to transplantation (also called chronic or destination therapy). The current generation of devices provides a differentiated spectrum of circulatory support. The major limitations of mechanical circulatory support devices are infection, coagulopathies and device dysfunction. The Scientific Council on Mechanical Circulatory Support of the International Society for Heart and Lung Transplantation has established an international database to generate critical data to advance knowledge about the effectiveness of mechanical circulatory support device therapy for one of the most difficult and costly contemporary medical problems, the malignant syndrome of advanced heart failure.

Scientific Registry of the International Society for Heart and Lung Transplantation: Introduction to the 2009 Annual Reports

We enthusiastically present the 2011 Annual Reports of the Scientific Registry (the Registry) of the International Society for Heart and Lung Transplantation (ISHLT). The Registry has now collected, analyzed, and reported data for more than 142,000 heart, heart-lung, and lung transplants. We are delighted to announce a new reporting relationship with L’agence de la Biomedicine, which allows us, for the first time, to add to the Registry data related to more than 13,000 heart, heart-lung, and lung transplants performed in France between April 1968 and December 2009. The addition of the French data, in combination with continued participation of more than 200 other centers worldwide (Appendix), has resulted in the past year being our most active to date (Table 1). We also note a transition in Registry report authorship: Dr Christian Benden is the first author of this year’s Pediatric Lung and Heart-Lung Transplant report, and will assume the position of Associate Medical Director from Dr Paul Aurora, who has served extremely ably in that capacity since 2007. There are many ways to access the Transplant Registry data. As in past years, all of the data figures and tables included in the Registry reports are also available on the ISHLT Web site (www.ishlt.org/registries) in the Microsoft PowerPoint (Microsoft Corp, Redmond, WA) format. The Web site also contains many additional data slides that are not included in the published reports. Those who wish to

How to improve organ donation: results of the ISHLT/FACT poll.

BACKGROUND Worldwide organ shortages remain a long-standing problem. Efforts to address this have ranged from attempts to improve public awareness to modified mandated choice systems; most have been unsuccessful. In the face of this intractable problem, increased consideration has been given to direct and indirect compensation, and in certain countries, black markets for organs have developed. To examine the attitudes of the transplant medical community regarding these issues, we surveyed members of the International Society for Heart and Lung Transplantation (ISHLT) in conjunction with the Foundation for the Advancement of Cardiac Therapies (FACT). METHODS/RESULTS We asked for opinions about how to improve organ donation. Of 739 respondents, 75% supported presumed consent, and 39% identified it as the single best way to increase donation; improved public education was a distant second (18%). Seventy percent supported indirect compensation (e.g., payment of funeral expenses, donation to a charity of the familys choice), and 66% opposed direct compensation (e.g., tax credit, life insurance benefit). When asked whether next of kin should be consulted regarding organ donation, and 84.2% responded affirmatively. However, of these individuals, 77.2% did not think that consultation should be required if the potential donor already had signed a donor card. MEMBERSHIP Our membership dramatically favors indirect over direct compensation as a way of increasing organ donation. The majority also favors the wishes of the individual over the family in determining donor status. However, presumed consent is the single best way to significantly improve organ donation, according to the majority of our respondents. More effort should be directed toward policy in these areas as opposed to improving public education, which has failed to yield satisfactory results.

Registry of the International Society for Heart and Lung Transplantation: A Quarter Century of Thoracic Transplantation

ide the an b he rt r p f the I ep n of c ith t stry. C wn i tted t tively p ata v affiliorts f ort r be o est a lung t dies r of s w ete a d app ed a s stical s ing R req to d the s gory o ulty A SHLT R c of r ties. T e: to o rom t ning o in e art a ulty A MD, M evelo a P v e are pleased to present the 2008 annual repor he Scientific Registry of the International Society eart and Lung Transplantation (the Registry). This arks the 25th anniversary of the Registry; since 1 he Registry has collected and reported data regard ore than 80,000 heart transplants and more t 9,000 lung and heart–lung transplants ( Table 1). The ast year has also been our most active to date, ,276 transplants added to the Registry from more 00 centers worldwide. Much gratitude is owed the m eart and lung transplant surgeons and physicians, clin oordinators, data coordinators and organ-exchange or izations (OEOs) throughout the world, whose timely ccurate submission of data has made attaining th ilestones possible (see Appendix). We also report some transitions in Registry re uthorship. This year Dr Richard Kirk authored ediatric Heart Transplant report; we thank Dr M oucek, author of the first 10 Pediatric Heart Transp eports, for his singular contribution to the Regis uccess. We also welcome Anna Kucheryavaya to egistry data analysis team. There are many ways to access the the ISHLT Re ata. As in past years, all of the data figures and ncluded in the Registry reports are also available iewing and downloading from the ISHLT web www.ishlt.org/registries) in MS P OWERPOINT format. he website also contains many additional data sl hat are not included in the published reports. Fur hose wishing to view the published heart, lung eart–lung and pediatric reports online may do so ontacting www.cardiosource.com. In addition to t nformation available in the published Registry repo nd slide sets, continentand center-specific data

The registry of the international society for heart and lung transplantation: introduction to the twentieth annual reports—2003

We are pleased to present the Twentieth Annual Reports of the Scientific Registry of the International Society for Heart and Lung Transplantation (the Registry). The mission of the Registry is to advance the state of knowledge and patient care regarding therapies for the failing heart and lung by: analyzing outcomes and treatment modalities for advanced heart and lung failure and transplantation; serving as a resource for health-care providers, governmental agencies, patient-related organizations and pharmaceutical companies seeking information regarding patient care and outcomes; and providing benchmark aggregate data for use by individual centers to assess their center-specific practices and outcomes. For the first time, all of the Registry reports are being published in a single issue of this journal; these include reports on the Adult Heart, Adult Lung and Heart–Lung, Pediatric Heart and Lung, and Mechanical Circulatory Support Device (MCSD) Database. The Registry remains the world’s most comprehensive record of heart and lung transplant activity, practices and outcomes. At present, the Registry contains data regarding 62,851 heart transplants, 2,955 heart–lung transplants and 15,199 lung transplants. More than 220 centers from 24 countries submit data to the Registry (Appendix), and participation in the Registry is open to any center in the world performing heart or lung transplantation. We wish to extend our sincere thanks to the many thoracic transplant surgeons, physicians and data coordinators in transplant programs throughout the world, whose timely and accurate submission of data has made these analyses possible. In what follows, we relate information regarding progress made toward reaching our 2002–2003 goals: (1) increasing worldwide heart and lung transplant reporting; (2) initiation of the MCSD Database; and (3) facilitation of access to data for clinical inquiries and research projects.

The Registry of the International Society for Heart and Lung Transplantation: past, present and future

The International Heart and Lung Transplant Registry (the Registry) is widely recognized as the most authoritative source of aggregated worldwide data regarding thoracic organ transplant activity, morbidity and mortality. Maintenance of the Registry is a major activity of the International Society for Heart and Lung Transplantation (ISHLT), and a source of great pride and visibility for the Society. The Registry currently publishes an Annual Report, a Pediatric Report, and a set of graphs and data tables. In addition to its regular data reporting functions, the Registry has also served as a source of information for Society members and non-members, and for more detailed analyses of specific research questions, which have formed the basis for more than 20 scientific publications. Dr. Michael Kaye served as Medical Director of the Registry from 1983 to 1993; under Dr. Kaye’s leadership the Registry grew from humble beginnings into a respected resource for information regarding heart and lung transplantation. In 1994, Dr. Jeffrey Hosenpud was appointed Medical Director and data collection and analysis was sub-contracted to the United Network for Organ Sharing (UNOS) foundation. Under Dr. Hosenpud’s stewardship, the Registry has grown to include data regarding more than 60,000 heart transplants and more than 12,000 lung and heart–lung transplants. At present, more than 223 centers from 18 countries submit data to the Registry. Participation in the Registry is open to any center in the world performing heart and/or lung transplantation.

ISHLT International Registry for Heart and Lung Transplantation - three decades of scientific contributions.

The International Registry for Heart and Lung Transplantation (Registry) was established by the International Society for Heart and Lung Transplant (ISHLT) in 1983. It has since become the largest repository of heart and lung transplant data in the world. The continued relevance of the Registry and its high impact scientific contributions have been possible through accountability and responsible governance. This manuscript describes the logistics of the Registrys operations, its goals and future directions.