Andrew Lindstrom
Arena Pharmaceuticals, Inc.
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Publication
Featured researches published by Andrew Lindstrom.
Bioorganic & Medicinal Chemistry Letters | 2012
Sergio G. Duron; Andrew Lindstrom; Celine Bonnefous; Hui Zhang; Xiaohong Chen; Kent T. Symons; Marciano Sablad; Natasha Rozenkrants; Yan Zhang; Li Wang; Nahid Yazdani; Andrew K. Shiau; Stewart A. Noble; Peter Rix; Tadimeti S. Rao; Christian A. Hassig; Nicholas D. Smith
The overproduction of nitric oxide during the biological response to inflammation by the nitric oxide synthase (NOS) enzymes have been implicated in the pathology of many diseases. By removal of the amide core from uHTS-derived quinolone 4, a new series highly potent heteroaromatic-aminomethyl quinolone iNOS inhibitors 8 were identified. SAR studies led to identification of piperazine 22 and pyrimidine 32, both of which reduced plasma nitrates following oral dosing in a mouse lipopolysaccharide challenge assay.
Archive | 2005
Cunxiang Zhao; James W. Malecha; Stewart A. Noble; Sergio G. Duron; Andrew Lindstrom; Andrew K. Shiau
Archive | 2005
Stewart A. Noble; Guy Oshiro; James W. Malecha; Cunxiang Zhao; Carmen Ka Man Robinson; Sergio G. Duron; Michael Sertic; Andrew Lindstrom; Andrew K. Shiau; Christopher D. Bayne; Mehmet Kahraman; Boliang Lou; Steve P. Govek
Bioorganic & Medicinal Chemistry Letters | 2007
Philip J. Skinner; Martin C. Cherrier; Peter J. Webb; Young-Jun Shin; Tawfik Gharbaoui; Andrew Lindstrom; Vu Hong; Susan Y. Tamura; Huong T. Dang; Cameron Pride; Ruoping Chen; Jeremy G. Richman; Daniel T. Connolly; Graeme Semple
Archive | 2007
Jeffrey Roger Roppe; Celine Bonnefous; Nicholas D. Smith; Andrew Lindstrom; Stewart A. Noble; Christian A. Hassig; Joseph E. Payne; Hui Zhuang; Xiaohong Chen; Sergio G. Duron
Bioorganic & Medicinal Chemistry Letters | 2007
Tawfik Gharbaoui; Philip J. Skinner; Young-Jun Shin; Claudia Averbuj; Jae-Kyu Jung; Benjamin R. Johnson; Tracy Duong; Marc Decaire; Jane Uy; Martin C. Cherrier; Peter J. Webb; Susan Y. Tamura; Ning Zou; Nathalie Rodriguez; P. Douglas Boatman; Carleton R. Sage; Andrew Lindstrom; Jerry Xu; Thomas O. Schrader; Brian Smith; Ruoping Chen; Jeremy G. Richman; Daniel T. Connolly; Steven L. Colletti; James R. Tata; Graeme Semple
Archive | 2008
Nicholas D. Smith; Celine Bonnefous; Hui Zhuang; Xiaohong Chen; Sergio G. Duron; Andrew Lindstrom
Archive | 2006
James W. Malecha; Andrew Lindstrom; Sergio G. Duron; David J. Thomas
Archive | 2006
James W. Malecha; Andrew Lindstrom; Sergio G. Duron; Steven P. Govek
Archive | 2006
James W. Malecha; Andrew Lindstrom; Sergio G. Duron; Steven P. Govek
