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Anett Ullrich

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Publication

Featured researches published by Anett Ullrich.

Biospektrum | 2015

Methoden zur Transportercharakterisierung in primären Hepatozyten

Markus Keiser; Jia Jia; Werner Siegmund; Anett Ullrich; Dieter Runge

Primary mammalian hepatocytes are used for several in vitro applications like drug metabolism and toxicity assays. The influence of substances on uptake and efflux transporters has to be evaluated during development as well. Therefore, we characterized the uptake and the efflux transport of different substrates in appropriate hepatocytes of different species.

ALTEX-Alternatives to Animal Experimentation | 2009

Long Term Cultures of Primary Human Hepatocytes as an Alternative to Drug Testing in Animals

Anett Ullrich; Donna B. Stolz; Ewa Ellis; Stephen C. Strom; George K. Michalopoulos; Jan G. Hengstler; Dieter Runge

ALTEX-Alternatives to Animal Experimentation | 2007

Use of a standardised and validated long-term human hepatocyte culture system for repetitive analyses of drugs: repeated administrations of acetaminophen reduces albumin and urea secretion.

Anett Ullrich; Berg C; Jan G. Hengstler; Dieter Runge

Molecular Medicine Reports | 2008

Anticancer drug cis-4-hydroxy-L-proline: Correlation of preclinical toxicology with clinical parameters of liver function

Heather Dickens; Anett Ullrich; Dieter Runge; Berno Mueller; Ulrike Olszewski; Gerhard Hamilton

Drug Metabolism and Pharmacokinetics | 2018

Establishing a platform of uptake transporters in HEK-293 cells for the analysis of possible drug–drug-interactions

Jia Jia; Anett Ullrich; Claudia Garve; Dieter Runge; Markus Keiser

Toxicology Letters | 2017

Establishing a platform of uptake transporters in HEK-293 cells for the analysis of possible drug–drug interactions

Anett Ullrich; Jia Jia; Claudia Garve; Markus Keiser; Dieter Runge

Toxicology Letters | 2016

Characterization of stably transfected HEK-293 cells expressing uptake transporters using fluorescent substances

Jia Jia; Anett Ullrich; Claudia Garve; Markus Keiser; Dieter Runge

Toxicology Letters | 2015

Characterization of transporter activities in fresh isolated primary hepatocytes of different species by using fluorescent substrates

Anett Ullrich; Jia Jia; Dieter Runge

Toxicology Letters | 2015

Characterization of stably transfected HEK-293 cells expressing OATPs using fluorescent substances

Jia Jia; Claudia Garve; Markus Keiser; Dieter Runge; Anett Ullrich

The FASEB Journal | 2009

Metabolism of the analgesic flupirtin in man

Eberhard Scheuch; Karen Methling; Anett Ullrich; Dieter Runge; Bernd Terhaag; Werner Siegmund

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Collaboration

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Dieter Runge

University of Pittsburgh

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Jia Jia

University of Greifswald

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Markus Keiser

University of Greifswald

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Jan G. Hengstler

Technical University of Dortmund

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Werner Siegmund

University of Greifswald

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Donna B. Stolz

University of Pittsburgh

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George K. Michalopoulos

University of Pittsburgh

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Ewa Ellis

Karolinska University Hospital

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Stephen C. Strom

Karolinska Institutet

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Bernd Terhaag

Dresden University of Technology

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