Anne V. Clough

Regional transit time estimation from image residue curves

AbstractMethods for estimating regional flow from digital angiography or dynamic computed tomography images require determination of indicator mean transit time (

In vivo detection of hyperoxia-induced pulmonary endothelial cell death using 99mTc-Duramycin

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Lung Circulation Modeling: Status and Prospect

) through a region-of-interest (ROI). We examine how the ROI kinematics and input dispersion influence the recovery of

Biomarkers for Radiation Pneumonitis Using Noninvasive Molecular Imaging

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Differential responses of targeted lung redox enzymes to rat exposure to 60 or 85% oxygen

using a computer-simulated vessel network representing that which might occur in a real organ. The network simulates flow through a large artery branching into two small arteries, each feeding a system of smaller vessels intended to represent capillaries and small vessels below the resolution of the imaging system. The capillaries are drained by a similar system of veins. Concentration curves measured over the inlet to the network and microvascular ROI residue curves are simulated. When the area-height ratio of the microvascular ROI curve is used and all of the indicator is contained within the ROI for at least one time point,