Annie Saint-Remy
University of Liège
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Featured researches published by Annie Saint-Remy.
European Journal of Clinical Nutrition | 2001
Dominique Paulus; Annie Saint-Remy; Michel Jeanjean
Objective of the present study: To analyse the usual dietary habits of Belgian adolescents from a high cardiovascular risk population.Methods: A food frequency questionnaire (57 items) was administered to the whole sample. Complementary questions specified some types of food (eg fat content). A subgroup of 234 adolescents gave detailed information on portion size (picture book and food samples).Setting: Twenty-four secondary schools in the Belgian province of Luxembourg.Subjects: A total of 1526 adolescents (12–17 y) selected by a multiclustered stage sampling (participation: 83.6%).Results: Respectively 46% and 60% of the adolescents did not eat fruit and vegetables daily. Most of the adolescents (72%) consumed at least one dairy product daily. The frequent consumption of chocolate and French fries indicated the strong cultural influence on dietary habits while imported foods (like hamburgers) had little success. One-third of the adolescents (33%, n=509) drank alcohol at least once a week and this proportion rose to 57% in the oldest age group. Boys and girls differed significantly in their diet, with girls choosing healthier foods. Dietary habits, in particular drinking habits, differed also significantly between education levels, assessed by the learning option of the participants. The semi-quantitative questionnaire showed that two-thirds of the adolescents had a lipid intake (mainly saturated fatty acids) which exceeded 35% of the total caloric intake. Complex carbohydrates represented less than half of the total carbohydrates intake.Conclusion: The study of the diet of Belgian adolescents confirmed the strong influence of tradition, in particular on the consumption of high fat content foods. The promotion of healthy diet in adolescents should consider the cultural influence, even for this young age group.European Journal of Clinical Nutrition (2001) 55, 130–136
European Journal of Epidemiology | 1999
Dominique Paulus; Annie Saint-Remy; Michel Jeanjean
Introduction: the Belgian province of Luxembourg has a high incidence of cardiovascular (CV) disease according to the MONICA register. Surveys conducted in adults and children have also found high CV risk factor levels in this province. Design: cross-sectional study. Objective of the present study: to collect data about blood pressure (BP) and its determinants in adolescents from this high CV risk population and to analyse their relationship. Participants: 1526 adolescents (12–17 years) in 24 secondary schools of the province. Results: mean systolic BP levels were 125 mm Hg (sd = 12 mm Hg) and 122 mm Hg (sd = 11 mm Hg) for boys and girls, respectively. Mean diastolic BP was equal to 74 mm Hg (sd = 10 mm Hg) in both genders. Systolic BP increased with age and differed significantly between genders from 15 years onwards. Body fatness indices increased with age except waist-to-hip ratio in girls and triceps skinfold in boys. Regression models including age, anthropometric indices and physical activity explained a small percentage of BP variance (for systolic BP, 2 = 0.21 and 0.12 for boys and girls, respectively). Weight was the first parameter related to BP in correlation and regression analyses. Conclusions: this study showed high BP and body fatness indices in adolescents from a high CV risk population. The model under study showed a moderate relationship between body fatness and BP. This finding suggests other influences as a genetic component to account for the high levels observed.
Scandinavian Journal of Clinical & Laboratory Investigation | 2009
Pierre Delanaye; Etienne Cavalier; Annie Saint-Remy; Laurence Lutteri; Jean-Marie Krzesinski
Background. The prevalence of stage 3 chronic kidney disease (CKD) is increasing, calculated using the modification of diet in renal disease (MDRD) study equation for estimating glomerular filtration rate (GFR). Cystatin C‐based equations are also being used to estimate GFR. Using creatinine‐based and cystatin C‐based equations, the aim of our study was to measure the difference in prevalence of stage 3 CKD in a population. Methods. CKD screening is organized in the Province of Liège, Belgium. On a voluntary basis, people aged between 45 and 75 years are invited for screening. GFR is estimated using the MDRD study equation and by the three recent cystatin C‐based equations proposed by Leveys group. The Levey 1 equation is based on cystatin C only and the Levey 2 equation on cystatin C corrected for age and sex. The Levey 3 equation combines cystatin C, creatinine, age and sex. Results. The population screened comprised 754 people. Cystatin C is highly correlated with creatinine (r = 0.6196, p<0.0001). Prevalence of stage 3 CKD when GFR is estimated by the MDRD equation study is 17.2 %, which is significantly and much higher than the prevalence obtained when cystatin C‐based equations are used. Indeed, prevalence is 2 %, 3.3 % and 5.8 % with the Levey 1, 2 and 3 equations, respectively. Conclusions. The prevalence of stage 3 CKD varies strongly following the method used for estimating GFR, creatinine‐based or cystatin C‐based equations. Such discrepancies must be confirmed and explained in additional studies using GFR measured with a reference method.
Contraception | 2000
Dominique Paulus; Annie Saint-Remy; Michel Jeanjean
The objective of the present study was to analyze the pattern of oral contraceptive (OC) use in teenagers and to examine the relationship between OC use and other cardiovascular risk factors. The study was conducted in 24 Belgian secondary schools. Most students (1526 adolescents aged 12-17 years) agreed to participate (participation rate: 83.6%). Smoking, physical activity habits, menarche, and OC use were assessed by a self-administered questionnaire. Total cholesterol level, blood pressure and anthropometric measurements were also measured. Fourteen per cent of mature girls (14%, n = 92) were OC users. Two-thirds of them (66.3%, n = 61) were taking OC which contained either gestodene or desogestrel. Blood pressure and BMI were similar for OC users and non-users. Total cholesterol level was significantly higher in OC users than in non-users (191 mg/dL versus 172 mg/dL). Logistic regression model confirmed the significant influence of OC use on total cholesterol level (OR = 3.08). OC users were also often smokers (39% versus 20% for non-users). In conclusion, the present study has found significant relationships between OC use and cardiovascular risk factors i.e., high total cholesterol and smoking. The first implication is a need for further research on lipoprotein profile in young OC users. Secondly, the combined use of OC and smoking in teenagers calls for preventive actions.
BMC Nephrology | 2012
Annie Saint-Remy; Mélanie Somja; Karen Gellner; Laurent Weekers; Catherine Bonvoisin; Jean-Marie Krzesinski
BackgroundIn kidney transplant (Kt) recipients , hypertension is a major risk for cardiovascular complications but also for graft failure. Blood pressure (BP) control is therefore mandatory. Office BP (OBP) remains frequently used for clinical decisions, however home BP (HBP) have brought a significant improvement in the BP control. Sodium is a modifiable risk factor, many studies accounted for a decrease of BP with a sodium restricted diet. Increased potassium intake has been also recommended in hypertension management. Using an agreement between office and home BP, the present study investigated the relations between the BP control in Kt recipients and their urinary excretion and dietary consumption of sodium and potassium.MethodsThe BP control defined by OBP <140/90 mmHg and HBP <135/85 mmHg was tested in 70 Kt recipients (mean age 56 ± 11.5 years; mean graft survival 7 ± 6.6 years) treated with antihypertensive medications. OBP and HBP were measured with a validated oscillometric device (Omron M6®). The 24-hour urinary sodium (Na+) and potassium (K+) excretions as well as dietary intakes were compared between controlled and uncontrolled (in office and at home) recipients. Non parametric Wilcoxon Mann–Whitney Test was used for between groups comparisons and Fishers exact test for frequencies comparisons. Pearson correlation coefficients and paired t-test were used when sample size was >30.ResultsUsing an agreement between OBP and HBP, we identified controlled (21%) and uncontrolled recipients (49%). Major confounding effects susceptible to interfere with the BP regulation did not differ between groups, the amounts of sodium excretion were similar (154 ± 93 vs 162 ± 88 mmol/24 h) but uncontrolled patients excreted less potassium (68 ± 14 vs 54 ± 20 mmol/24 h; P = 0.029) and had significantly lower potassium intakes (3279 ± 753 vs 2208 ± 720 mg/24 h; P = 0.009), associated with a higher urinary Na+/K + ratio. Systolic HBP was inversely and significantly correlated to urinary potassium (r = −0.48; P = 0.002), a positive but non significant relation was observed with urinary sodium (r = 0,30;P = 0.074).ConclusionsHalf of the treated hypertensive Kt recipients remained uncontrolled in office and at home. Restoring a well-balanced sodium/potassium ratio intakes could be a non pharmacological opportunity to improve blood pressure control.
Journal of Hypertension | 2010
Annie Saint-Remy; Jean-Marie Krzesinski
Aim: The present study aimed to define reference values of central blood pressure (cBP) and Pulse Wave Velocity (PWV) together with 24H ABPM in healthy normotensive young adults before starting a follow-up of their CV profile modifications over time. Method: Office BP (OBP), heart rate (HR), cBP and PWV (SphygmoCor) and 24 h ABPM (Spacelabs 90207) were measured in 94 healthy young caucasian (mean age: 22.5 ± 2.8 y, range:19–30; M/W:47/47). Height, weight, family and personal medical history, smoking and physical activity were recorded. None were under antihypertensive medications; 86% of women were on pill. Results: Mean BMI was 21.6 ± 3 Kg/m2. Twelve % were smokers, 26% and 21% had a family history of HT and Diabetes, respectively. Mean OBP in men was 123–74 mmHg with 95th P at 139- 87 and mean cBP was 103–73 with the 95th P at 116–85, mean 24hABPM was 120–69 with a 95th P at 131–78 mmHg. In women the mean BP and 95th P were for OBP: 116–71,132–88; for cBP: 99–72,119–88; and for 24hABPM: 113–70,127–80.Boys,taller and heavier, had significantly higher OBP, cBP, Pulse Pressure (PP) and Systolic ABPM than girls. Mean PWV was 5.8 ± 0.9 m/s with a P90th at 7 m/s. PWV was moderately related to cBP (r = 0.27, P = 0.01). Girls had systematically higher HR than boys. cSBP was correlated to 24 h ABP (0.44, P < 0.0001), to 24 h MAP (0.51, P < 0.0001). Interestingly, participants with a family history of HT and/or diabetes,had a higher PWV (P = 0.07) than those with no family history. Conclusions: Observed in a healthy population, our data provide reference values of central BP and PWV for a 20–30 y. range of age. OBP and Daytime ABPM were very close while Central Systolic BP were significantly lower. These data give opportunity to follow up this population regarding the BP evolution with age and cardiovascular risk factors appearance according to these three ways of measurement and to compare these relations in different pathologies and treatment related to high blood pressure.
American Journal of Hypertension | 2004
Annie Saint-Remy; Fatima Ait Oile; Laurent Weekers; Bernard Dubois; Jean-Marie Krzesinski
Abstract P-247 Key Words: Antihypertensive Drugs, Renal Transplant Recipients, Immunosuppressive Drug
Clinical Nephrology | 2000
Ma Fontaine; Adelin Albert; Bernard Dubois; Annie Saint-Remy; Georges Rorive
Vascular Health and Risk Management | 2005
Annie Saint-Remy; Jean-Marie Krzesinski
Environmental Health Perspectives | 1990
Robert Lauwerys; Antoon Amery; Alfred Bernard; P. Bruaux; Jean-Pierre Buchet; F Claeys; Pierre De plaen; G. Ducoffre; Robert Fagard; Paul Lijnen; Laurence Nick; Harry Roels; Désiré Rondia; Annie Saint-Remy; Francis Sartor; Jan A. Staessen