Ashok K. Kalla

Flavonol glycosides of Phlomis spectabilis

Abstract Four flavonol glucosides, one new, have been isolated from a methanolic extract of Phlomis spectabilis . Their structures were established as the 3-glucosides and 3-(6″-( E )- p -coumaroyl)glucosides of kaempferol and of kaempferol 7,4′-dimethyl ether.

Revised structures of daturalactone and 12-oxowithanolide

Abstract Recently Dhar et al. reported the isolation of two new steroidal lactones from the leaves of Datura quercifolia HBK and formulated them as 5α,12α,17α-trihydroxy-1-oxo-6α, 7α-epoxy-22 S -witha-2,24-dienolide and 5α,17α-dihydroxy-1, 12-dioxo-6α,7α-epoxy-22 S -witha-2,24-dienolide on the basis of UV, IR, NMR and MS studies. Further detailed chemical and spectral studies have led to revised structures, namely 5α, 12α-dihydroxy-1-oxo-6α,7α: 24α, 25α-diepoxy-20 S , 22 R -with-2-enolide and 5α-hydroxy-1, 12-dioxo-6α, 7α: 24α, 25α-diepoxy-20 S , 22 R -with-2-enolide, respectively, for the above two compounds.

Koelpinin-A, B and C — three triterpenoids from Koelpinia linearis

Three new triterpenoids, designated as koelpinin-A, B and C and characterised as 28-nor-lup-12,17-dien-3 beta,16 alpha-diol,3 beta-acetoxy-28-nor-lup-12,17-dien-16 alpha-ol and 28-nor-lup-12,17-dien-3 beta-ol-16-one, respectively, together with 30-nor-lup-3 beta-ol-20-one, taraxeryl acetate and germanicol, were isolated, from the aerial parts of Koelpinia linearis. 13C-NMR shifts were assigned after performing APT and DEPT experiments.

Isoflavones of Iris spuria

Abstract A new isoflavone, 5,7-dihydroxy-6,2′-dimethoxyisoflavone, together with iristectorigenin A and iristectorin A were isolated and characterized from the methanol extract of Iris spuria .

Unusual homologous long-chain alkanoic acid esters of lupeol from Koelpinia linearis

Abstract An unusual series of five long-chain alkanoic acid (C 14 C 18 ) esters of lupeol was isolated from the methanol extract of koelpinia linearis and characterized by chemical and spectroscopic methods, including 13 C NMR. The spectral assignments were achieved by APT and DEPT techniques.

28-Noroleana-16,21-diene triterpenes from Phlomis spectabilis

Abstract Two new nortriterpenes have been isolated from Phlomis spectabilis and characterised as 28-noroleana-16,21-diene-3α,19α,23,29-tetrol and 28-noroleana-16,21-diene-3α,19α,29-triol-23-al.

Triterpenoids from Swertia petiolata

Abstract From the petrol extract of Swertia petiolata a new natural triterpene, 3β-hydroxylup-13(18)-ene has been isolated in addition to 3β-hydroxylup-12en-28-oic acid and ursolic acid.

Isocladrastin and kashmigenin—two isoflavones from Iris kashmiriana

Abstract From the rhizomes of the Iris kashmiriana , two new isoflavones, isocladrastin and kashmigenin, were characterized as 3′-hydroxy-6,7-4′-trimethoxy-isoflavone and 4′-hydroxy-3′,5′-dimethoxy-6,7-methylenedioxy-isoflavone, respectively. Also, junipegenin-B has been found present in this plant species.

A cinnamoyl pyrrolidine amide from Piper peepuloides

Analysis of a petrol extract of the leaves of Piper peepuloides resulted in the isolation of a new cinnamoyl pyrrolidine amide characterized as Z-pyrrolidine-1-3-(6-methoxy-1,3-benzodioxol-5-yl)-1-oxo-2-propenyl along with peepuloidin, 2-methoxy-4,5-methylenedioxy-Z-cinnamoyl piperidide, β-sitosterol and β-sitosterol glucoside.

Isomeric 2,3-seco-hopene lactones from Swertia petiolata

Abstract Two novel isomeric hopene triterpenes, Swertialactone C and Swertialactone D have been isolated from Swertia petiolata. Their structures were established as 2,3-seco-2 → 3 lactone, 1β,3β-epoxy-hop-17(21)-ene and 2,3-seco-2 → 3 lactone, 1β,3β-epoxy-hop-16-ene, respectively.