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Dive into the research topics where Beatrix Merla is active.

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Featured researches published by Beatrix Merla.


Journal Fur Praktische Chemie-chemiker-zeitung | 1999

Aminoalkylation of cyclic and acyclic alkyl vinyl ethers

Beatrix Merla; Nikolaus Risch

The aminoalkylation of cyclic and acyclic alkyl vinyl ethers from inexpensive starting materials yields Mannich bases 4 and 10. Preformed and in situ generated iminium salts are used under mild reaction conditions. In some cases it is possible to isolate the α-halogenated 1,3-amino ethers 3 which have so far only ever been assumed to exist. Furthermore, the preparation of the already known 1-benzotriazolyl-3-aminoalkyl ethers 6 and 9 using this methodology is also successful.


Archive | 2004

Spirocyclic cyclohexane derivatives with affinity for the orl1-receptor

Claudia Hinze; Bernd Sundermann; Hans Schick; Birgitta Henkel; Werner Englberger; Stefan Oberbörsch; Elmar Friderichs; Sven Frormann; Babette-Yvonne Kögel; Klaus Linz; Beatrix Merla; Derek Saunders; Wolfgang Schröder; Helmut Dr. Sonnenschein


Archive | 2010

Substituted nicotinamides as KCNQ2/3 modulators

Sven Kühnert; Beatrix Merla; Gregor Bahrenberg; Wolfgang Schröder


Archive | 2007

Substituted tetrahydropyrrolopyrazine compounds having affinity with the kcnq2/3 k+ channel and use thereof in medicaments

Beatrix Merla; Thomas Christoph; Stefan Oberbörsch; Klaus Schiene; Gregor Bahrenberg; Robert Frank; Sven Kühnert; Wolfgang Schröder


Archive | 2006

Benzo[d]isoxazol-3-yl-amine Compounds and Their Use as Vanilloid Receptor Ligands

Robert Frank; Beatrix Merla; Melanie Reich; Ruth Jostock


Archive | 2006

Substituted Benzo[d]isoxazol-3-yl Amine Compounds as Analgesics

Beatrix Merla; Robert Frank; Gregor Bahrenberg; Wolfgang Schröder; Saskia Zemolka


Archive | 2005

Substituted 5-aminomethyl-1H-pyrrole-2-carboxamides

Beatrix Merla; Corinna Sundermann; Utz-Peter Jagusch; Werner Englberger; Hagen-Heinrich Hennies; Babette-Yvonne Kögel


Synlett | 1997

A Simple and Highly Diastereoselective One-Pot Synthesis of 1,3-Diamines

Beatrix Merla; Michael Arend; Nikolaus Risch


Archive | 2007

Spirocyclic cyclohexane derivative with analgesic properties

Beatrix Merla; Stefan Oberbörsch; Bernd Sundermann; Werner Englberger; Hagen-Heinrich Hennies; Babette-Yvonne Kögel; Stephan Schunk; Heinz Graubaum


Archive | 2009

Substituted 4,5,6,7-tetrahydrothienopyridines as kcnq2/3 modulators for treating pain, epilepsy and urinary incontinence

Sven Kühnert; Gregor Bahrenberg; Achim Kless; Beatrix Merla; Klaus Schiene; Wolfgang Schröder

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