Benjamin Alan Anderson

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Featured researches published by Benjamin Alan Anderson.

Tetrahedron Letters | 1995

Acylation of oxazoles by the copper-mediated reaction of oxazol-2-ylzinc chloride derivatives

Nancy Kay Harn; Christine J. Gramer; Benjamin Alan Anderson

Abstract C-2 acylation of oxazole derivatives is accomplished by reaction of oxazol-2-ylzinc chloride reagents with acid chlorides in the presence of cuprous iodide. O-acylated vinylisonitriles, which are the sole product from the corresponding reaction employing lithiooxazole, are not observed. The method accommodates substituted and unsubstituted oxazoles with a variety of acid chlorides.

Bioorganic & Medicinal Chemistry Letters | 1999

Synthesis and anticonvulsant activity of 3-aryl-5H-2,3-benzodiazepine ampa antagonists

Benjamin Alan Anderson; Nancy Kay Harn; Marvin M. Hansen; Allen R. Harkness; David Lodge; J. David Leander

A novel series of 3-aryl-5H-2,3-benzodiazepines with N-3 aromatic substituents has been synthesized. Good in vivo anticonvulsant activity of the new compounds has been demonstrated employing the maximal electroshock seizure test in mice. Evaluation of a subset of the compounds in the cortical wedge assay confirmed the new structures to be AMPA antagonists.

Journal of Organic Chemistry | 1998

Cooperative Catalyst Effects in Palladium-Mediated Cyanation Reactions of Aryl Halides and Triflates

Benjamin Alan Anderson; Edward C. Bell; Francis O. Ginah; Nancy Kay Harn; Lisa M. Pagh; James P. Wepsiec

Journal of the American Chemical Society | 1995

APPLICATION OF A PRACTICAL BIOCATALYTIC REDUCTION TO AN ENANTIOSELECTIVE SYNTHESIS OF THE 5H-2,3-BENZODIAZEPINE LY300164

Benjamin Alan Anderson; Marvin M. Hansen; Allen R. Harkness; Cynthia L. Henry; Jeffrey T. Vicenzi; Milton Joseph Zmijewski

Journal of Organic Chemistry | 1997

Application of Palladium(0)-Catalyzed Processes to the Synthesis of Oxazole-Containing Partial Ergot Alkaloids

Benjamin Alan Anderson; Lisa M. Becke; Richard N. Booher; Michael Edward Flaugh; Nancy Kay Harn; Thomas J. Kress; David L. Varie; James P. Wepsiec

Synthesis | 1996

Palladium-Catalyzed Cross Coupling Reactions of Oxazol-2-ylzinc Chloride Derivatives

Benjamin Alan Anderson; Nancy Kay Harn

Archive | 1999

Substituted carbazoles, process for their preparation and their use as sPLA2 inhibitiors

Benjamin Alan Anderson; Nicholas James Bach; Jolie Anne Bastian; Nancy Kay Harn; Richard Waltz Harper; Gary Alan Hite; Michael Dean Kinnick; Ho-Shen Lin; Richard J. Loncharich; John Mcneill Mcgill; Edward David Mihelich; Jr John Michael Morin; Michael Leroy Phillips; Michael Enrico Richett; Daniel Jon Sall; Jason Scott Sawyer; Richard Walter Schevitz

Archive | 1995