Network


Latest external collaboration on country level. Dive into details by clicking on the dots.

Hotspot


Dive into the research topics where John Robert Rizzo is active.

Publication


Featured researches published by John Robert Rizzo.


Tetrahedron | 2000

Enantioselective Syntheses of 1-Carbacephalosporins from Chemoenzymically Derived β-Hydroxy-α-Amino Acids: Applications to the Total Synthesis of Carbacephem Antibiotic Loracarbef

Billy Grinnell Jackson; Steve W Pedersen; Jack W. Fisher; Jerry Wayne Misner; John P. Gardner; Michael A. Staszak; Christopher W. Doecke; John Robert Rizzo; James Abraham Aikins; Eugene Farkas; Kristina L Trinkle; Jeffrey T. Vicenzi; Matt R. Reinhard; Eugene Paul Kroeff; Chris A Higginbotham; Robert James Gazak; Tony Y. Zhang

Abstract Serine hydroxymethyltransferase (SHMT) derived from recombinant E. coli was found to be able to catalyze the condensation between glycine and 4-pentenaldehyde, affording enantiopure l -erythro-2-amino-3-hydroxy-6-heptenoic acid (AHHA) in high yield and throughput. Conversion of this chiral intermediate of biosynthetic origin to the oral carbacephalosporin antibiotic loracarbef (Lorabid®) via β-lactam forming reactions and subsequent Dieckmann cyclization was achieved.


Archive | 2009

Inhibitors of diacylglycerol acyltransferase

Macklin Brian Arnold; Thomas James Beauchamp; Emily J. Canada; Erik James Hembre; Jianliang Lu; John Robert Rizzo; John Mehnert Schaus; Qing Shi


Archive | 1997

Non-peptidyl vasopressin V1a antagonists

Robert F. Bruns; Robin D. G. Cooper; Bruce A. Dressman; David C. Hunden; Stephen W. Kaldor; Gary A. Koppel; John Robert Rizzo; Jeffrey J. Skelton; Mitchell I. Steinberg


Bioorganic & Medicinal Chemistry Letters | 2005

2-Alkoxydihydrocinnamates as PPAR agonists. Activity modulation by the incorporation of phenoxy substituents.

Jose Alfredo Martin; Dawn A. Brooks; Lourdes Prieto; Rosario Gonzalez; Alicia Torrado; Isabel Rojo; Beatrriz Lopez De Uralde; Carlos Lamas; Rafael Ferritto; María Martín-Ortega; Javier Agejas; Francisco Parra; John Robert Rizzo; Gary A. Rhodes; Roger L. Robey; Charles A. Alt; Samuel R. Wendel; Tony Y. Zhang; Anne Reifel-Miller; Chahrzad Montrose-Rafizadeh; Joseph T. Brozinick; Eric Hawkins; Elizabeth A. Misener; Daniel A. Briere; Robert Ardecky; James D. Fraser; Alan M. Warshawsky


Tetrahedron Letters | 2008

An expedient synthesis of 3-substituted indoles via reductive alkylation with ketones

John Robert Rizzo; Charles A. Alt; Tony Y. Zhang


Archive | 2000

Preparation of substituted piperidin-4-ones

John Robert Rizzo; Michael A. Staszak; Tony Y. Zhang


Archive | 2000

Compounds useful as neuro-protective agents

Jill Ann Panetta; John Kevin Shadle; Lawrence Joseph Heinz; Michael Leroy Phillips; John Robert Rizzo; Benjamin Alan Anderson; John Allan Rieck; David L. Varie


Archive | 1997

Inhibitors of the enzymatic activity of psa

Benjamin Alan Anderson; Gerald W. Becker; James A. Carty; Nancy Kay Harn; Lowell D. Hatfield; Blake Lee Neubauer; John Robert Rizzo; Tony Y. Zhang


Journal of Heterocyclic Chemistry | 1989

Alkylation studies with 5-cyano-1H-pyrazole-4-carboxylic acid, ethyl ester

James R. Beck; James Abraham Aikins; Michael P. Lynch; John Robert Rizzo; Eddie Vi-Ping Tao


Journal of Heterocyclic Chemistry | 1988

A novel regioselective t-butylation as applied to the synthesis of 5-cyano-1-(1,1-dimethylethyl)-N-methyl-1H-pyrazole-4-carboxamide

Eddie Vi-Ping Tao; James Abraham Aikins; John Robert Rizzo; James R. Beck; Michael P. Lynch

Collaboration


Dive into the John Robert Rizzo's collaboration.

Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Researchain Logo
Decentralizing Knowledge