Bernard R. Neustadt | Researchain

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Archive | 2000

Piperazine derivatives useful as CCR5 antagonists

Bahige M. Baroudy; John W. Clader; Hubert Josien; Stuart W. McCombie; Brian Mckittrick; Michael W. Miller; Bernard R. Neustadt; Anandan Palani; Elizabeth M. Smith; Ruo W. Steensma; Jayaram R. Tagat; Susan F. Vice; Mark Laughlin; Eric J. Gilbert; Marc Labroli

Archive | 2002

ADENOSINE A2a RECEPTOR ANTAGONISTS

Bernard R. Neustadt; Neil Lindo; William J. Greenlee; Deen Tulshian; Lisa S. Silverman; Yan Xia; Craig D. Boyle; Samuel Chackalamannil

Journal of Medicinal Chemistry | 1997

Potent tetracyclic guanine inhibitors of PDE1 and PDE5 cyclic guanosine monophosphate phosphodiesterases with oral antihypertensive activity.

Ho-Sam Ahn; Ana Bercovici; George Boykow; Alan Bronnenkant; Samuel Chackalamannil; Jason Chow; Renee Cleven; John A. Cook; Michael Czarniecki; Carol Domalski; Ahmad Fawzi; Michael V. Green; Asli Gündes; Ginny D. Ho; Malvina Laudicina; Neil Lindo; Ke Ma; Mahua Manna; Brian Mckittrick; Bita Mirzai; Terry Nechuta; Bernard R. Neustadt; Chester Puchalski; Kathryn Pula; Lisa S. Silverman; Elizabeth M. Smith; Andrew Stamford; Richard P. Tedesco; Hsingan Tsai; Deen Tulshian

Journal of Medicinal Chemistry | 2001

Piperazine-Based CCR5 Antagonists as HIV-1 Inhibitors. II. Discovery of 1-[(2,4-Dimethyl-3-pyridinyl)carbonyl]-4- methyl-4-[3(S)-methyl-4-[1(S)-[4-(trifluoro- methyl)phenyl]ethyl]-1-piperazinyl]- piperidine N1-Oxide (Sch-350634), an Orally Bioavailable, Potent CCR5 Antagonist

Jayaram R. Tagat; Ruo W. Steensma; Stuart W. McCombie; Dennis V. Nazareno; Sue-Ing Lin; Bernard R. Neustadt; Kathleen Cox; Serena Xu; Lisa Wojcik; Michael G. Murray; Nicole Vantuno; and Bahige M. Baroudy; Julie M. Strizki

Journal of Medicinal Chemistry | 1988

Synthesis and pharmacological activity of angiotensin converting enzyme inhibitors: N-(mercaptoacyl)-4-substituted-(S)-prolines.

Elizabeth M. Smith; Gerald F. Swiss; Bernard R. Neustadt; Elijah H. Gold; Jane A. Sommer; Arthur Brown; Peter J.S. Chiu; Rosa Moran; Edmund J. Sybertz; Thomas Baum

Journal of Medicinal Chemistry | 1973