Bibiana Pérez

Pityriasis rubra pilaris and human immunodeficiency virus infection

Recently, the occurrence of pityriasis rubra pilaris (PRP) has been reported in patients with HIV infection. It presents different clinical features, and has a poorer prognosis, than the classical adult type of PRP. We report the occurrence of severe PRP in an HlV‐infected patient, and review the previously reported cases of this association. We propose the designation of a new category of PRP (type 6), characterized by the presence of HIV infection, usually without immunosuppression, a poor prognosis and response to treatment, and the development of nodulocystic and lichen spinulosus lesions.

Complications of 585-nm pulsed dye laser therapy

Background

Progressive ascending telangiectasia treated with the 585nm flashlamp-pumped pulsed dye laser

Progressive ascending telangiectasia (PAT) is a distinct entity with telangiectatic superficial vessels on lower extremities as its main clinical feature. A relationship with occult infections and response to antibiotic and antifungal drugs have been described, although not all cases can be successfully managed with these therapies. Our objective was to treat a woman with PAT that had failed to respond to systemic antibiotic and antifungal drugs.

8-MOP bath PUVA in the treatment of psoriasis : clinical results in 42 patients

We report the clinical results of 8-MOP bath PUVA in 42 psoriasis patients. The PASI was used to assess disease severity and improvement after topical PUVA therapy. PASI reduction was 72.51% for the whole treated group, with a greater response in those patients with palmoplantar psoriasis and guttate psoriasis. We also observed a better response in patients with skin phototypes II and III. Treatment was well tolerated although some adverse effects were observed.

Self-healing cutaneous mucinosis

Self-healing juvenile cutaneous mucinosis is a new entity distinct from previously described forms of cutaneous mucinosis. We present a new case in a 26-year-old female patient who began abruptly with a papular eruption, involving the scalp, face, neck and trunk, accompanied by periarticular papules on the hands and arthralgias. No associated disease could be detected and the lesions resolved spontaneously within a few months. This is the first case described in an adult patient.

Successful treatment of erosive vulvar lichen sclerosus with methylaminolaevulinic acid and laser-mediated photodynamic therapy

© 2008 The Authors JEADV 2009, 23 , 70–110 Journal compilation

PRIMARY ANETODERMA AND ORBITAL PSEUDOTUMOR

A 31-year-old healthy woman with a 6-month history of swelling, erythema, and pain of her superior right eyelid was referred to the department of ophthalmology. She had no complaints of decreased vision or diplopia. The general examination was normal. On ophthalmologic examination, the lacrimal glands of both eyes were enlarged. Visual acuity, color vision, pupillary examination, applanation tonometry, slit lamp examination, and fundoscopy were normal. There was limitation of internal superior and lateral gazes and ptosis in both eyes. Basal tear secretion was diminished. Blood chemistry profile, complete blood cell count, tuberculin test, rheumatoid factor, serum and urine calcium, and urinalysis were normal or negative. Antinuclear antibody test was positive at 1:80 and plasma immunoglobulins were increased. Abdominal and chest x-ray, gallium gammagraphy, and a pulmonary diffusion test were also normal. A computerized tomogram of the orbits showed an enlargement of both lacrimal glands without involvement of adjacent muscles and bone (Fig. 1). A fine needle aspiration biopsy showed a cellular pattern of nonspecific orbital inflammation.

Minocycline hydrochloride hyperpigmentation complicating treatment of pyoderma gangrenosum.

Minocycline‐associated hyperpigmentation is an uncommon side effect We report the case of a patient with pyoderma gangrenosum successfully treated with oral minocycline but complicated by marked hyperpigmentation in his pyoderma gangrenosum and acne scars. One of the clinical forms of minocycline hyperpigmentation includes dark‐blue or black macules in depressed acne scars or other sites of skin inflammation; this pattern seems to be independent of the total cumulative dose and the skin process.

Fluorescence diagnosis and photodynamic therapy for Bowen’s disease treatment

Introduction  It has already been demonstrated the high efficacy of photodynamic therapy (PDT) for Bowen’s disease (BD) treatment. Fluorescence diagnosis consists on registration of the fluorescence emitted by tissue after application of a photosensitizer, indicating presence of tumoral cells. It has been described as a useful tool for actinic keratosis. Different results have been published about fluorescence diagnosis for basal cell carcinomas. Very few reports about the role of fluorescence diagnosis for this entity exist and this is the first one which correlates the fluorescence image after PDT with the histopathological response.

MYCOSIS FUNGOIDES WITH SIGNET-RING CELLS AND MONOCLONAL GAMMOPATHY

A 73‐year‐old white woman was admitted to our hospital for evaluation of a chronic dermatitis. Personal history was remarkable only for arterial hypertension and noninsulin‐dependent6 diabetes mellitus. Clinical and histopathologic findings were consistent with a diagnosis of mycosis fundoides (mf and staging procedures including bolld cell counts, serum biochemistry, urinalysis, bone marrow biopsy, Sé zary cell counts in peripheral bolld, computerized tomography (ct scans, abdominal ultrasonography, chest roentgenograms, serum protein electrophoresis, and immunoelectrophoresis disclosed normal or negative results (T2 N0 M0 B0).