C Creuzot

Macular sensitivity and structure in epiretinal membranes 6 months after surgical treatment

Purpose To evaluate the evolution of macular sensitivity (MS) and its correlation with visual acuity (VA) and Spectral‐Domain Optical Coherence Tomography (SD‐OCT) in patients with idiopathic epiretinal membrane (ERM) at 3 and 6 months after surgical treatment.

Compared effectiveness of brilliant blue G for internal limiting membrane peeling in idiopathic epiretinal membrane in novice and experimented surgeons

Purpose To evaluate the reliability of expected peeled surface after internal limiting membrane (ILM) removal by junior and senior surgeons with or without Brilliant Blue G (BBG) dye.

Maintenance of anticoagulant and antiplatelet agents for patients undergoing vitreoretinal surgery

Purpose To establish the prevalence of anticoagulant, aspirin, and clopidogrel use in patients undergoing vitreoretinal surgery, and to compare the outcome of peribulbar anesthesia between users and non‐users.

Corneal involvement of eyelids infections

Abstract not provided

Predictive factors of visual outcome in acute post-cataract endophthalmitis

Purpose To study potential clinical and microbiological predictive factors of visual outcome in patients with acute endophthalmitis following cataract surgery. Methods A prospective study included 100 patients in 4 University hospital.Factors related to the cataract surgery, the initial clinical presentation and the microbiological identification were analyzed according to the final visual outcome using univariate and multivariate (logistic regression) analysis. Results 46% out of the patients had a final visual acuity less than or equal to 0.3 logMar (good visual outcome) at 6 months while 10% had only light perceptions. Patients with good visual outcome differed for the duration of cataract surgery, initial visual acuity, the visibility of fundus and the identification of a coagulase negative staphylococcus. In contrast, patients with a poor visual outcome were older, had more cornea oedema and a more important hypopion at the admission, more complications at the time of cataract surgery. Furthermore a bacterium was more frequently identified in this latter group. Multivariate analysis showed that age, complications at the time of cataract surgery, microbiological identification, pars plana vitrectomy were independent predictive factors. Conclusion Factors of visual outcome in acute postcataract endophthalmitis identified in this prospective study were similar to that reported during the Endophthalmitis Vitrectomy Study 10 years ago. As part of the treatment, pars plana vitrectomy is associated with predictive factors of poor visual outcome. Identification of these predictive factors at presentation should allow a better management of patients needed an aggressive treatment.

Corneal bacterial infections

Purpose To present the main causes of corneal bacterial infections and suggest an appropriate management. Methods Bacterial keratitis is the most common cause of infected corneal ulceration. The epidemiology of corneal bacterial diseases and their risk factors will be studied. The initial presentation is important to determine the potential stain responsible for the infection and to assess the overall severity of the disease. Local and general criteria evaluations are needed to adapt the treatment. Results Specific signs to identify bacteria remain rare but some signs can help to determine the first line treatment. However laboratory methods remain the only way to diagnose a corneal bacterial disease with certainty. However the aspect of the infiltrate, the intraocular involvement and the condition of the patient may influence the outcome. The treatment is based on an initial broad-spectrum antibacterial therapy with secondary adaptation to the identified bacteria. Conclusion Multiple microorganisms are involved in corneal infections. Local and systemic risk factors have to be identified to treat these diseases in emergency still considered as a leading cause of visual loss.

Retinal nerve fiber layer thickness and central corneal thickness in ocular hypertensive patients and healthy subjects

Purpose To establish the correlation between central corneal thickness (CCT) and retinal nerve fiber layer (RNFL) thickness in ocular hypertensive patients and healthy subjects. Methods We prospectively collected charts of healthy subjects and ocular hypertensive (OHT) patients in one academic center between 2007 and 2008. OHT patients were defined by two measurements of intraocular pressure superior to 21mmHg without treatment, open angle in gonioscopy, normal appearing optic nerve head and normal visual field test Standard Automated Perimetry (SAP SITA) and Frequency Doubling Technique (FDT). Every patient underwent a standard clinical examination including optic nerve head examination, intraocular pressure, CCT measurement by ultrasonic (US) and anterior segment OCT pachymetry, visual field testing (SAP and FDT), RNFL thickness by scanning laser polarimetry (GDX-VCC) and optical coherence tomography (OCT). Results Eighty healthy subjects and 60 OHT patients were included. A correlation between US CCT and OCT CCT was found in both groups (r2=0.85 and r2= 0.87, p 0.15) in GDX-VCC and OCT RNFL thickness in both groups. In controls there was no correlation of any RNFL thickness measurement with the CCT. In OHT patients, the US CCT was weakly correlated with the average TSNIT evaluated by GDX-VCC (r2= 0.04, p<0.02). Conclusion This study did not show any relevant correlation between the RNFL thickness evaluated by GDX-VCC and the US CCT in healthy individuals and in OHT patients with a normal FDT.