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Charles E. Grimshaw

University of California, Berkeley

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Publication

Featured researches published by Charles E. Grimshaw.

Biochemistry | 1994

Tyrosine-48 is the proton donor and histidine-110 directs substrate stereochemical selectivity in the reduction reaction of human aldose reductase: enzyme kinetics and crystal structure of the Y48H mutant enzyme.

Kurt M. Bohren; Charles E. Grimshaw; Chung Jeng Lai; David H. T. Harrison; Dagmar Ringe; Gregory A. Petsko; Kenneth H. Gabbay

Biochemistry | 1995

MECHANISM OF HUMAN ALDEHYDE REDUCTASE : CHARACTERIZATION OF THE ACTIVE SITE POCKET

Oleg A. Barski; Kenneth H. Gabbay; Charles E. Grimshaw; Kurt M. Bohren

Biochemistry | 1998

Synergistic kinetic interactions between components of the phosphorelay controlling sporulation in Bacillus subtilis.

Charles E. Grimshaw; Shaoming Huang; Conrad Hanstein; Mark A. Strauch; Ling Wang; James A. Hoch; John M. Whiteley

Biochemistry | 1995

HUMAN ALDOSE REDUCTASE : RATE CONSTANTS FOR A MECHANISM INCLUDING INTERCONVERSION OF TERNARY COMPLEXES BY RECOMBINANT WILD-TYPE ENZYME

Charles E. Grimshaw; Kurt M. Bohren; Chung-Jeng Lai; Kenneth H. Gabbay

Biochemistry | 1992

Aldose reductase: model for a new paradigm of enzymic perfection in detoxification catalysts.

Charles E. Grimshaw

Biochemistry | 1995

HUMAN ALDOSE REDUCTASE : PK OF TYROSINE 48 REVEALS THE PREFERRED IONIZATION STATE FOR CATALYSIS AND INHIBITION

Charles E. Grimshaw; Kurt M. Bohren; Chung-Jeng Lai; Kenneth H. Gabbay

Biochemistry | 1998

A Source of Response Regulator Autophosphatase Activity: The Critical Role of a Residue Adjacent to the Spo0F Autophosphorylation Active Site†

James Zapf; Madhusudan; Charles E. Grimshaw; James A. Hoch; Kottayil I. Varughese; John M. Whiteley

Biochemistry | 1990

Mechanistic basis for nonlinear kinetics of aldehyde reduction catalyzed by aldose reductase.

Charles E. Grimshaw; M. Shahbaz; C. G. Putney

Biochemistry | 1995

Human aldose reductase: subtle effects revealed by rapid kinetic studies of the C298A mutant enzyme.

Charles E. Grimshaw; Kurt M. Bohren; Chung-Jeng Lai; Kenneth H. Gabbay

Biochemistry | 2000

The Sorbinil Trap: A Predicted Dead-End Complex Confirms the Mechanism of Aldose Reductase Inhibition†

Kurt M. Bohren; Charles E. Grimshaw

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Kurt M. Bohren

Baylor College of Medicine

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Kenneth H. Gabbay

Baylor College of Medicine

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Chung-Jeng Lai

University of California

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John M. Whiteley

Scripps Research Institute

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James A. Hoch

Scripps Research Institute

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C. Grant Willson

University of Texas at Austin

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Dagmar Ringe

Brandeis University

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David H. T. Harrison

Rosalind Franklin University of Medicine and Science

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Gregory A. Petsko

Cornell University

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Henry Rapoport

University of California

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