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Chester Puchalski

Schering-Plough

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Publication

Featured researches published by Chester Puchalski.

Bioorganic & Medicinal Chemistry Letters | 1999

Synthesis and evaluation of potent and selective c-GMP phosphodiesterase inhibitors

Ginny D. Ho; Silverman Lisa; Ana Bercovici; Chester Puchalski; Deen Tulshian; Yan Xia; Michael Czarniecki; Michael J. Green; Renee Cleven; Hongtao Zhang; Ahmad Fawzi

Syntheses and structure-activity relationships (SAR) of cGMP selective phosphodiesterase inhibitors are discussed. Potent and selective inhibitors are produced when the C-2 position of tetracyclic guanine 1 is substituted with alkyl chains containing six carbon atoms.

Journal of Medicinal Chemistry | 1985

Antiulcer agents. 1. Gastric antisecretory and cytoprotective properties of substituted imidazo[1,2-a]pyridines

James J. Kaminski; James A. Bristol; Chester Puchalski; Raymond G. Lovey; Arthur J. Elliott; Henry Guzik; Daniel M. Solomon; David J. Conn; Martin S. Domalski

Journal of Medicinal Chemistry | 1989

Antiulcer agents. 4. Conformational considerations and the antiulcer activity of substituted imidazo[1,2-a]pyridines and related analogues.

James J. Kaminski; Chester Puchalski; Daniel M. Solomon; Rizvi Rk; David J. Conn; Arthur J. Elliott; Raymond G. Lovey; Henry Guzik; Peter J.S. Chiu; James F. Long

Archive | 1982

Imidazo[1,2-A]pyridines and use

James A. Bristol; Chester Puchalski

Archive | 1981

Imidazo(1,2-a)pyridines, processes for their preparation and pharmaceutical compositions containing them

James A. Bristol; Chester Puchalski

Archive | 1982

Novel imidazo(1,2-a)pyridines and pyrazines, processes for their preparation and pharmaceutical compositions containing them

James A. Bristol; Chester Puchalski; Raymond G. Lovey

Archive | 1982

Antiulcer tricyclic imidazo [1,2-a]pyridines

Elijah H. Gold; James J. Kaminski; Chester Puchalski

Archive | 1981

Indoles in treatment of peptic ulcers

James A. Bristol; Chester Puchalski

Journal of Organic Chemistry | 1980

Synthesis and characterization of stereoisomeric 11-hydroxy-1,2,3,4,4a,5,6,11a-octahydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridines

James A. Bristol; Chester Puchalski

Archive | 1982

Foerfarande Foer framstaellning of pharmacologically vaerdefulla imidazo / 1,2-a / pyraziner.

James A. Bristol; Chester Puchalski; Raymond G. Lovey

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Collaboration

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James A. Bristol

University of New Hampshire

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Raymond G. Lovey

Schering-Plough

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James J. Kaminski

University of Kansas

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Arthur J. Elliott

Schering-Plough

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Daniel M. Solomon

Schering-Plough

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David J. Conn

Schering-Plough

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Henry Guzik

Schering-Plough

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Ahmad Fawzi

Schering-Plough

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Ana Bercovici

Schering-Plough

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Deen Tulshian

Schering-Plough

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