Claudia A. Sevillano

Genomic evaluation for a three-way crossbreeding system considering breed-of-origin of alleles

BackgroundGenomic prediction of purebred animals for crossbred performance can be based on a model that estimates effects of single nucleotide polymorphisms (SNPs) in purebreds on crossbred performance. For crossbred performance, SNP effects might be breed-specific due to differences between breeds in allele frequencies and linkage disequilibrium patterns between SNPs and quantitative trait loci. Accurately tracing the breed-of-origin of alleles (BOA) in three-way crosses is possible with a recently developed procedure called BOA. A model that accounts for breed-specific SNP effects (BOA model), has never been tested empirically on a three-way crossbreeding scheme. Therefore, the objectives of this study were to evaluate the estimates of variance components and the predictive accuracy of the BOA model compared to models in which SNP effects for crossbred performance were assumed to be the same across breeds, using either breed-specific allele frequencies (

Genome-wide association studies for tick resistance in Bos taurus × Bos indicus crossbred cattle : A deeper look into this intricate mechanism

{\text{G}}_{\text{A}}

Genotype by feed interaction for feed efficiency and growth performance traits in pigs

GA model) or allele frequencies averaged across breeds (

Correction to: Genomic evaluation for a three-way crossbreeding system considering breed-of-origin of alleles

{\text{G}}_{\text{B}}

Assigning breed origin to alleles in crossbred animals

GB model). In this study, we used data from purebred and three-way crossbred pigs on average daily gain (ADG), back fat thickness (BF), and loin depth (LD).ResultsEstimates of variance components for crossbred performance from the BOA model were mostly similar to estimates from models