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Dive into the research topics where D. W. Fry is active.

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Featured researches published by D. W. Fry.


Journal of Biological Chemistry | 1982

Rapid formation of poly-gamma-glutamyl derivatives of methotrexate and their association with dihydrofolate reductase as assessed by high pressure liquid chromatography in the Ehrlich ascites tumor cell in vitro.

D. W. Fry; J C Yalowich; I. D. Goldman


Cancer Research | 1983

Analysis of the Role of Membrane Transport and Polyglutamation of Methotrexate in Gut and the Ehrlich Tumor in Vivo as Factors in Drug Sensitivity and Selectivity

D. W. Fry; L. A. Anderson; M Borst; I. D. Goldman


Cancer Research | 1982

Teniposide (VM-26)- and etoposide (VP-16-213)-induced augmentation of methotrexate transport and polyglutamylation in Ehrlich ascites tumor cells in vitro.

J C Yalowich; D. W. Fry; Goldman Id


Cancer Research | 1983

Role of Methotrexate Polyglutamylation and Cellular Energy Metabolism in Inhibition of Methotrexate Binding to Dihydrofolate Reductase by 5-Formyltetrahydrofolate in Ehrlich Ascites Tumor Cells in Vitro

L. H. Matherly; D. W. Fry; I. D. Goldman


Cancer Research | 1985

Enhanced Polyglutamylation of Aminopterin Relative to Methotrexate in the Ehrlich Ascites Tumor Cell in Vitro

L. H. Matherly; M. K. Voss; L. A. Anderson; D. W. Fry; I. D. Goldman


Cancer Research | 1980

Effects of 2,4-dinitrophenol and other metabolic inhibitors on the bidirectional carrier fluxes, net transport, and intracellular binding of methotrexate in Ehrlich ascites tumor cells

D. W. Fry; White Jc; Goldman Id


Cancer Research | 1982

Augmentation of the Intracellular Levels of Polyglutamyl Derivatives of Methotrexate by Vincristine and Probenecid in Ehrlich Ascites Tumor Cells

D. W. Fry; J C Yalowich; I. D. Goldman


Cancer Research | 1980

Relationship between Membrane Transport of Methotrexate and Endogenous Cyclic Adenosine 3′:5′-Monophosphate in the Ehrlich Ascites Tumor

White Jc; R A Carchman; D. W. Fry; Goldman Id


Archive | 1982

Synthesis of polygammaglutamyl derivatives of methotrexate (MTX) in tumor bearing mice and its effect on drug pharmacokinetics in vivo; correlation of experimental data with computer simulations

D. W. Fry; Goldman Id; White Jc


Archive | 1981

accumulation methotrexate polyglutamates (MTX-PGs) in Ehrlich ascites tumor cells in vitro: Marked augmentation by vincristine

J C Yalowich; D. W. Fry; I. D. Goldman

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I. D. Goldman

Virginia Commonwealth University

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J C Yalowich

Virginia Commonwealth University

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Goldman Id

Virginia Commonwealth University

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White Jc

Virginia Commonwealth University

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L. A. Anderson

Virginia Commonwealth University

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L. H. Matherly

Virginia Commonwealth University

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M Borst

Virginia Commonwealth University

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M. K. Voss

Virginia Commonwealth University

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M. L. Hess

Virginia Commonwealth University

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R A Carchman

Virginia Commonwealth University

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