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I. D. Goldman

Virginia Commonwealth University

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Publication

Featured researches published by I. D. Goldman.

Journal of Biological Chemistry | 1982

Rapid formation of poly-gamma-glutamyl derivatives of methotrexate and their association with dihydrofolate reductase as assessed by high pressure liquid chromatography in the Ehrlich ascites tumor cell in vitro.

D. W. Fry; J C Yalowich; I. D. Goldman

Journal of Biological Chemistry | 1995

Characterization of a Mutation in the Reduced Folate Carrier in a Transport Defective L1210 Murine Leukemia Cell Line

Kevin E. Brigle; Michael J. Spinella; Esteban E. Sierra; I. D. Goldman

Journal of Biological Chemistry | 1995

Distinguishing between Folate Receptor-α-mediated Transport and Reduced Folate Carrier-mediated Transport in L1210 Leukemia Cells

Michael J. Spinella; Kevin E. Brigle; Esteban E. Sierra; I. D. Goldman

Cancer Research | 1984

Polyglutamylation, an Important Element in Methotrexate Cytotoxicity and Selectivity in Tumor versus Murine Granulocytic Progenitor Cells in Vitro

I. Fabre; G. Fabre; I. D. Goldman

Journal of Biological Chemistry | 1988

Evidence for a functional defect in the translocation of the methotrexate transport carrier in a methotrexate-resistant murine L1210 leukemia cell line.

J. D. Schuetz; L. H. Matherly; E H Westin; I. D. Goldman

Journal of Biological Chemistry | 1987

The effects on 4-aminoantifolates on 5-formyltetrahydrofolate metabolism in L1210 cells. A biochemical basis of the selectivity of leucovorin rescue.

L. H. Matherly; C. K. Barlowe; V. M. Phillips; I. D. Goldman

Cancer Research | 1983

Analysis of the Role of Membrane Transport and Polyglutamation of Methotrexate in Gut and the Ehrlich Tumor in Vivo as Factors in Drug Sensitivity and Selectivity

D. W. Fry; L. A. Anderson; M Borst; I. D. Goldman

Journal of Biological Chemistry | 1991

Characterization of two cDNAs encoding folate-binding proteins from L1210 murine leukemia cells. Increased expression associated with a genomic rearrangement.

Kevin E. Brigle; E H Westin; M T Houghton; I. D. Goldman

Journal of Biological Chemistry | 1984

Synthesis and properties of 7-hydroxymethotrexate polyglutamyl derivatives in Ehrlich ascites tumor cells in vitro.

G. Fabre; I. Fabre; L. H. Matherly; J. P. Cano; I. D. Goldman

Journal of Biological Chemistry | 1989

Folate-pool interconversions and inhibition of biosynthetic processes after exposure of L1210 leukemia cells to antifolates. Experimental and network thermodynamic analyses of the role of dihydrofolate polyglutamylates in antifolate action in cells.

R L Seither; D F Trent; D. C. Mikulecky; T. J. Rape; I. D. Goldman

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L. H. Matherly

Virginia Commonwealth University

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D. W. Fry

Virginia Commonwealth University

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E H Westin

Virginia Commonwealth University

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G. Fabre

Virginia Commonwealth University

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J C Yalowich

Virginia Commonwealth University

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Kevin E. Brigle

Virginia Commonwealth University

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R L Seither

Virginia Commonwealth University

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I. Fabre

Virginia Commonwealth University

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L. A. Anderson

Virginia Commonwealth University

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C. K. Barlowe

Virginia Commonwealth University

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