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L. H. Matherly

Virginia Commonwealth University

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Publication

Featured researches published by L. H. Matherly.

Journal of Biological Chemistry | 1988

Evidence for a functional defect in the translocation of the methotrexate transport carrier in a methotrexate-resistant murine L1210 leukemia cell line.

J. D. Schuetz; L. H. Matherly; E H Westin; I. D. Goldman

Journal of Biological Chemistry | 1987

The effects on 4-aminoantifolates on 5-formyltetrahydrofolate metabolism in L1210 cells. A biochemical basis of the selectivity of leucovorin rescue.

L. H. Matherly; C. K. Barlowe; V. M. Phillips; I. D. Goldman

Cancer Research | 1986

Antifolate Polyglutamylation and Competitive Drug Displacement at Dihydrofolate Reductase as Important Elements in Leucovorin Rescue in L1210 Cells

L. H. Matherly; C. K. Barlowe; I. D. Goldman

Cancer Research | 1984

Interactions between 7-hydroxymethotrexate and methotrexate at the cellular level in the ehrlich ascites tumor in vitro.

G. Fabre; L. H. Matherly; I. Fabre; Jean-Paul Cano; I. D. Goldman

Journal of Biological Chemistry | 1989

Membrane protein changes in an L1210 leukemia cell line with a translocation defect in the methotrexate-tetrahydrofolate cofactor transport carrier

J. D. Schuetz; E H Westin; L. H. Matherly; R. Pincus; P. S. Swerdlow; I. D. Goldman

Cancer Research | 1983

Role of Methotrexate Polyglutamylation and Cellular Energy Metabolism in Inhibition of Methotrexate Binding to Dihydrofolate Reductase by 5-Formyltetrahydrofolate in Ehrlich Ascites Tumor Cells in Vitro

L. H. Matherly; D. W. Fry; I. D. Goldman

Cancer Research | 1985

Enhanced Polyglutamylation of Aminopterin Relative to Methotrexate in the Ehrlich Ascites Tumor Cell in Vitro

L. H. Matherly; M. K. Voss; L. A. Anderson; D. W. Fry; I. D. Goldman

Cancer Research | 1984

Role of the Cellular Oxidation-Reduction State in Methotrexate Binding to Dihydrofolate Reductase and Dissociation Induced by Reduced Folates

L. H. Matherly; L. A. Anderson; I. D. Goldman

Archive | 1985

Polyglutamation of 2,4-diaminoantifolates as a critical determinant of leucovorin (LCV) rescue

L. H. Matherly; C. K. Barlowe; W. L. Banks; I. D. Goldman

Federation Proceedings | 1984

Pathways for the synthesis of 7-hydroxymethotrexate polyglutamyl derivatives

G. Fabre; L. H. Matherly; I. D. Goldman

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I. D. Goldman

Virginia Commonwealth University

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C. K. Barlowe

Virginia Commonwealth University

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L. A. Anderson

Virginia Commonwealth University

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D. W. Fry

Virginia Commonwealth University

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E H Westin

Virginia Commonwealth University

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G. Fabre

Virginia Commonwealth University

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J. D. Schuetz

Virginia Commonwealth University

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I. Fabre

Virginia Commonwealth University

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M. K. Voss

Virginia Commonwealth University

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P. S. Swerdlow

Virginia Commonwealth University

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