Dalia E. Mohamed

Synthesis and Surface Properties of Novel N-Alkyl Quinoline-Based Cationic Gemini Surfactants

Two series of cationic dimeric (gemini) surfactants are prepared with respect to key surfactants properties, such as surface activity and solubilization. The influence of both the dimerization and the spacer group is examined in order to establish structure-property relationships. The surface tension and critical micelle concentration can be markedly reduced compared to the monomeric surfactants in the pure state. The critical micelle concentration (cmc) of each series has been determined using equilibrium surface tension measurements. Furthermore, air/water interface parameters including effectiveness (πcmc), efficiency (PC20), maximum surface excess (Γ max ), and minimum surface area (A min ) have been also derived using Gibbs adsorption equation at 25°C. Standard free energies of micellization and adsorption were calculated. Solubilization behaviors of the synthesized surfactants were measured towards paraffin oil as solubilized material using light transmission technique.

Role of Surfactants in Regulation of Cancer Growth

Introduction: A brief review is presented in the field of petroleum carcinogenesis. Epidemiological surveys in occupationally exposed populations postulate that long exposure to polycyclic aromatic hydrocarbons (PAHs) is carcinogenic. Several novel surfactants were investigated by Badawi and his collaborators on regulation of cancer growth. Other investigators recorded the role of cationic surfactants and pegylation.

Anticancer cytotoxicity assessment of cationic surfactants metal complexes

Series of metal complexes (Cu, Co, Ni, Y) was prepared by the reaction of the different transition metals and three environmentally cationic surfactants derived from vanillin. Their chemical structures were confirmed using IR, NMR, UV-Vis, dynamic light scattering (DLS) spectroscopy, and zeta potential. The surface activities of the ligands and their metal complexes were measured using surface tension measurements. Their Surface and thermodynamic parameters were calculated at 25 o C. Chemical structure-surface activity relationship of the metal complexes was discussed. The anticancer cytotoxic assessment of the synthesized metal complexes showed promising results in the medicinal field.