David G. Corley

Convulsant alkaloids from Dioscorea dumetorum

Abstract Investigation of the West African medicinal yam Dioscorea dumetorum Pax has resulted in the isolation and stereostructural elucidation of the previously reported dihydrodioscorine as well as the new alkaloid dumetorine.

New trichothecene mycotoxins of Fusarium sporotrichioides (MC-72083)

Abstract Isolation and characterization of three new trichothecene mycotoxins from Fusarium sporotrichioides MC-72083 are reported. Structure and n.m.r. assignments were made using COSY, NOESY and INAPT as well as other spectroscopic techniques.

CD additivity in trichothecene benzoates: application as a microanalytical method for trichothecene characterization

Abstract The additivity relation in A values of split CD curves previously established with pyranose p-bromobenzoates was shown to be valid for p-bromobenzoates of the cage-like trichothecene system (which also possesses a primary hydroxyl group). This suggests that additivity is generally valid even for congested multichromophoric molecules. The relation has been integrated Into a new micro method for trichothecene characterization, which was applied to a new trichothecene from Fusarium sporotrichioides (MC-72083) at a sub- μg level.