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David R. Sibley

Office of Technology Transfer

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Publication

Featured researches published by David R. Sibley.

Archive | 2009

Molecular Pharmacology of the Dopamine Receptors

Michele L. Rankin; Lisa A. Hazelwood; R. Benjamin Free; Yoon Namkung; Elizabeth B. Rex; Rebecca A. Roof; David R. Sibley

Archive | 2014

11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepine s-oxide derivatives and their use as dopamine d2 receptor antagonists

Juan Jose Marugan; Jingbo Xiao; Marc Ferrer; Noel Terrence Southall; R. Benjamin Free; David R. Sibley

Archive | 2014

Investigation of the D1-D2 heteromer

Lani S. Chun; R. Benjamin Free; Trevor Doyle; Xi-Ping Huang; David R. Sibley

Catecholamine Research in the 21st Century#R##N#Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012 | 2014

Investigation of the D1-D2 heteromer: Pharmacology, subunit composition, and mechanisms of signaling

Lani S. Chun; R. Benjamin Free; Trevor Doyle; Xi Ping Huang; David R. Sibley

Catecholamine Research in the 21st Century#R##N#Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012 | 2014

Identification of Substituted Benzazepines as Functionally Selective Ligands of the D1 Dopamine Receptor

Jennie Conroy; R. Benjamin Free; Trevor Doyle; David R. Sibley

Archive | 2013

Table 7, Activity profile of the probe ML321 and relative analogs against D2 Ca2+ assay in D2 expressing HK293 T-Rex™ cell line, D2 β-arrestin assay in D2 receptor PathHunter® β-arrestin cells, D3 β-arrestin assay in D3 PathHunter® β-arrestin cells, and D2 or D3 radio-ligand binding assays in HEK cell line expressing either D2L or D3 human dopamine receptor

Jingbo Xiao; R. Benjamin Free; Elena Barnaeva; Jennie Conroy; Trevor Doyle; Marthe Bryant-Genevier; Mercedes K. Taylor; Noel Southall; Xin Hu; Marc Ferrer; Steve Titus; Wei Zheng; David R. Sibley; Juan J. Marugan

Archive | 2013

Table 6, List of the D2 DAR inhibitor probe ML321 and related analogs and their corresponding identification numbers

Jingbo Xiao; R. Benjamin Free; Elena Barnaeva; Jennie Conroy; Trevor Doyle; Marthe Bryant-Genevier; Mercedes K. Taylor; Noel Southall; Xin Hu; Marc Ferrer; Steve Titus; Wei Zheng; David R. Sibley; Juan J. Marugan

Archive | 2013

Table 2, Detailed protocol of DiscoveRx D2 β-arrestin secondary assay

Jingbo Xiao; R. Benjamin Free; Elena Barnaeva; Jennie Conroy; Trevor Doyle; Marthe Bryant-Genevier; Mercedes K. Taylor; Noel Southall; Xin Hu; Marc Ferrer; Steve Titus; Wei Zheng; David R. Sibley; Juan J. Marugan

Archive | 2013

Table 10, Comparison of dopamine receptor inhibition assay for ML321 and current D2 antagonists

Jingbo Xiao; R. Benjamin Free; Elena Barnaeva; Jennie Conroy; Trevor Doyle; Marthe Bryant-Genevier; Mercedes K. Taylor; Noel Southall; Xin Hu; Marc Ferrer; Steve Titus; Wei Zheng; David R. Sibley; Juan J. Marugan

Archive | 2013

Scheme 1, The synthetic route to ML321 is a multi-step process with 8 compound intermediates (A – H)

Jingbo Xiao; R. Benjamin Free; Elena Barnaeva; Jennie Conroy; Trevor Doyle; Marthe Bryant-Genevier; Mercedes K. Taylor; Noel Southall; Xin Hu; Marc Ferrer; Steve Titus; Wei Zheng; David R. Sibley; Juan J. Marugan

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R. Benjamin Free

National Institutes of Health

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Trevor Doyle

Purdue University

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Jennie Conroy

National Institutes of Health

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Elena Barnaeva

National Institutes of Health

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Jingbo Xiao

National Institutes of Health

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Juan J. Marugan

National Institutes of Health

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Marc Ferrer

National Institutes of Health

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Mercedes K. Taylor

Icahn School of Medicine at Mount Sinai

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Noel Southall

National Institutes of Health

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Steve Titus

National Institutes of Health

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