Fernando Canova

History of vascular reactivity models and their involvement in hypertension pathogenesis

Hypertension is a silent and multifactorial disease. Over two centuries ago, the first device to record blood pressure was developed, making it possible to determine normotension and to establish criteria for hypertension. Since then, several studies have contributed to advance knowledge in this area, promoting significant advances in pharmacological treatments and, as a result, increasing survival of hypertensive people. The main models developed for the study of hypertension and the main findings in the vascular area are included in this review. We considered aspects related to vascular reactivity, changes in the population, and action of beta adrenergic receptors in the pathogenesis of hypertension.

CRIAÇÃO DE MATERIAL DIDÁTICO DE CIÊNCIAS BIOLÓGICAS PARA ENSINO MÉDIO

Introdução Uma das grandes preocupações entre professores é a de promover o emprego de metodologias que estejam comprometidas com uma aprendizagem que proporcione apreensão do conteúdo de forma mais eficaz e significativa (MOREIRA, 2006). Os recursos didáticos vêm mostrando elementos essenciais para o processo de ensino-aprendizagem, são ferramentas que viabilizam a construção do conhecimento. Essas ferramentas, quando bem elaboradas e utilizadas, contribuem para a construção do conhecimento dos alunos. O material didático pode ser definido amplamente com produtos pedagógicos utilizados na educação, e especificamente, com material instrucional que se elabora com finalidade didática. O jogo didático vem trazendo resultados satisfatórios no processo de aprendizagem (BANDEIRA, 2012). Konrath et al. (2005) defende que os recursos podem e devem ser inseridos na educação de forma que possam enriquecer o processo de ensino –aprendizagem. O jogo quando é bem planejando é um recurso pedagógico eficiente obtendo toda atenção do aluno. Dessa forma, os objetivos deste trabalho são criação de material didático de Ciências Biológica na forma de um jogo de baralho voltado para o ensino médio.

STUDY OF THE ACUTE AND CHRONIC EFFECTS OF MANUAL THERAPY ON THE SALIVARY MELATONIN CONCENTRATION IN STUDENTS PREPARING TO APPLY FOR THE UNIVERSITIES

Isabela V. Vieira (IC), Heloísa Ap. Ferreira (PQ), Aglécio Luiz de Souza (PQ), Fernando Canova (PQ). Dora M. Grassi-Kassisse (PQ). Abstract The entrance exam is a stressful experience for students. The manual therapy (MT) act as an strategy to confront the stressor agent (coping). To evaluate the effects of MT we analyzed the salivary concentration of melatonin, a counter regulatory hormone of stress, produced by the pineal gland.

Analysis of acute and chronic stress by quantification of cortisol in saliva and hair, BDNF in saliva and analysis of Val66Met the BDNF polymorphism in graduating: announcement of a pilot study

Cortisol is considered as the stress hormone. BDNF is involved in plasticity, including memory, learning and sleep. The hair cortisol assess chronic stress. Our goals are the standardization of cortisol quantification techniques in hair (chronic), BDNF in saliva and the polymorphism identification in this population.

APPLICATION OF THEORY IN PRACTICE: INTEGRATING AREAS - exact and biological- IN GRADUATE - Study of ECC in hypertensive rats.

Bruna Sabrina Hergert (IC), Ana Gabriela Conceição-Vertamatti (PQ), Larissa Yuri Ishizu (PQ), Luiz Alberto Ramos (PQ), Gustavo Trevisan Costa (IC), Fernando Canova (PQ). Laura Leticia Ramos Rifo (PQ), Dora M. Grassi-Kassisse (PQ). Abstract Exact and Biological sciences are areas of expertise that complement each other. The associations between these areas are little explored in the formation of graduate student. Proposals to recruit students of exact for help with the analysis of the data obtained in Labeest generated great interest of applicants’ scholarship BAS-SAE. Data analysis electrocardiography of models of hypertension in rats was carried out by a student of statistics, which can apply their knowledge acquired during their training.

Acute and Chronic Effects of Tantric Yoga Practice on Distress Index

OBJECTIVES To evaluate the acute and chronic effects of yoga practice. DESIGN Quantitative study using a one-group pre-posttest design. SETTING Visão Futuro Institute, Porangaba, São Paulo, Brazil. PARTICIPANTS 22 volunteers (7 men and 15 women). INTERVENTION Six weeks of a tantric yoga program (TYP), 50 minutes per session, held twice a week from 8 a.m. to 9 a.m. The local ethics committee approved the protocol. OUTCOME MEASURES Data were collected in the first week and at the end of the sixth week of TYP. Salivary cortisol concentration (SCC) was used to measure physiology of distress and to analyze the short- and long-term effects of TYP. Psychological distress was evaluated by applying a specific perceived stress questionnaire (PSQ). Results (mean±standard deviation) were analyzed by Wilcoxon test (p<0.05). RESULTS SCC decreased 24% after the first (0.66±0.20 μg/dL versus 0.50±0.13 μg/dL) and last (1.01±0.37 versus 0.76±0.31 μg/dL) sessions, showing the short-term effect of yoga. Long-term effects were analyzed by daily rhythm of cortisol production. In the beginning, volunteers showed altered SCC during the day, with nighttime values (0.42±0.28) higher than those at noon (0.30±0.06). After the TYP, SCC was higher in the morning (1.01±0.37) and decreased during the day, with lower values before sleep (0.30±0.13). The TYP was also efficient to reduce PSQ scores (0.45±0.13 versus 0.39±0.07). Specifically, the irritability, tension, and fatigue domains on the PSQ decreased (0.60±0.20 versus 0.46±0.13), as did the fear and anxiety domains (0.54±0.30 versus 0.30±0.20). CONCLUSION Over the short term, TYP led to the decrease of cortisol production. Over the long term, TYP induced higher cortisol production in the morning and lower production in the evening. Those effects contributed to the physical and mental well-being of the participants.