Douglas Mccord Sammond
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Publication
Featured researches published by Douglas Mccord Sammond.
Bioorganic & Medicinal Chemistry Letters | 2009
Kirk L. Stevens; Krystal J. Alligood; Jennifer G. Badiang Alberti; Thomas R. Caferro; Stanley D. Chamberlain; Scott Howard Dickerson; Hamilton D. Dickson; Holly Kathleen Emerson; Robert J. Griffin; Robert D. Hubbard; Barry R. Keith; Robert J. Mullin; Kimberly G. Petrov; Roseanne M. Gerding; Michael J. Reno; Tara Renae Rheault; David W. Rusnak; Douglas Mccord Sammond; Stephon C. Smith; David E. Uehling; Alex G. Waterson; Edgar R. Wood
A novel class of pyrrolidinyl-acetyleneic thieno[3,2-d]pyrimidines has been identified which potently inhibit the EGFR and ErbB-2 receptor tyrosine kinases. Synthetic modifications of the pyrrolidine carbamate moiety result in a range of effects on enzyme and cellular potency. In addition, the impact of the absolute stereochemical configuration on cellular potency and oral mouse pharmacokinetics is described.
Archive | 2003
Stanley D. Chamberlain; Mui Cheung; Holly Kathleen Emerson; Neil W. Johnson; Kristen E. Nailor; Douglas Mccord Sammond; Marcus Semones
Bioorganic & Medicinal Chemistry Letters | 2006
John F. Miller; C. Webster Andrews; Michael Stephen Brieger; Eric S. Furfine; Michael R. Hale; Mary H. Hanlon; Richard J. Hazen; Istvan Kaldor; Ed W. McLean; David J. Reynolds; Douglas Mccord Sammond; Andrew Spaltenstein; Roger D. Tung; Elizabeth M. Turner; Robert X. Xu; Ronald G. Sherrill
Bioorganic & Medicinal Chemistry Letters | 2005
Douglas Mccord Sammond; Kristen E. Nailor; James M. Veal; Robert T. Nolte; Liping Wang; Victoria B. Knick; Sharon K. Rudolph; Anne T. Truesdale; Eldridge N. Nartey; Jeffrey A. Stafford; Rakesh Kumar; Mui Cheung
Bioorganic & Medicinal Chemistry Letters | 2009
Alex G. Waterson; Kimberly G. Petrov; Keith R. Hornberger; Robert D. Hubbard; Douglas Mccord Sammond; Stephon C. Smith; Hamilton D. Dickson; Thomas R. Caferro; Kevin W. Hinkle; Kirk L. Stevens; Scott Howard Dickerson; David W. Rusnak; Glenn M. Spehar; Edgar R. Wood; Robert J. Griffin; David E. Uehling
Archive | 2005
Jerzy Ryszard Szewczyk; Jason D. Speake; Douglas Mccord Sammond; Ronald George Sherrill
Bioorganic & Medicinal Chemistry Letters | 2005
Ronald G. Sherrill; Eric S. Furfine; Richard J. Hazen; John F. Miller; David J. Reynolds; Douglas Mccord Sammond; Andrew Spaltenstein; Pat Wheelan; Lois L. Wright
Archive | 2007
Stanley D. Chamberlain; Mui Cheung; Holly Kathleen Emerson; Neil W. Johnson; Kristen E. Nailor; Douglas Mccord Sammond; Marcus Semones
Archive | 2005
Jerzy Ryszard Szewczyk; Jason D. Speake; Douglas Mccord Sammond; Ronald George Sherrill
Archive | 2005
David E. Uehling; Kirk L. Stevens; Scott Howard Dickerson; Alex G. Waterson; Philip A. Harris; Douglas Mccord Sammond; Robert D. Hubbard; Holly Kathleen Emerson; Joseph W. Wilson
