Eduardo Setti
Cephalon
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Publication
Featured researches published by Eduardo Setti.
Bioorganic & Medicinal Chemistry Letters | 2011
Mark W. Holladay; Brian T. Campbell; Martin W. Rowbottom; Qi Chao; Kelly G. Sprankle; Andiliy G. Lai; Sunny Abraham; Eduardo Setti; Raffaella Faraoni; Lan Tran; Robert C. Armstrong; Ruwanthi N. Gunawardane; Merryl D. Cramer; Dana Gitnick; Mark A. Ator; Bruce D. Dorsey; Bruce R. Ruggeri; Michael Williams; Shripad S. Bhagwat; Joyce James
Aryl phenyl ureas with a 4-quinazolinoxy substituent at the meta-position of the phenyl ring are potent inhibitors of mutant and wild type BRAF kinase. Compound 7 (1-(5-tert-butylisoxazol-3-yl)-3-(3-(6,7-dimethoxyquinazolin-4-yloxy)phenyl)urea hydrochloride) exhibits good pharmacokinetic properties in rat and mouse and is efficacious in a mouse tumor xenograft model following oral dosing.
Archive | 2010
Gang Liu; Qi Chao; Michael J. Hadd; Mark W. Holladay; Sunny Abraham; Eduardo Setti
Archive | 2009
Sunny Abraham; Shripad S. Bhagwat; Brian T. Campbell; Qi Chao; Raffaella Faraoni; Mark W. Holladay; Andiliy G. Lai; Martin W. Rowbottom; Eduardo Setti; Kelly G. Sprankle
Archive | 2011
Sunny Abraham; Shripad S. Bhagwat; Michael J. Hadd; Mark W. Holladay; Gang Liu; Zdravko V. Milanov; Hitesh K. Patel; Eduardo Setti; Janice Sindac
Archive | 2011
Raffaella Faraoni; Michael J. Hadd; Mark W. Holladay; Martin W. Rowbottom; Eduardo Setti
Archive | 2011
Raffaella Faraoni; Michael J. Hadd; Mark W. Holladay; Martin W. Rowbottom; Eduardo Setti
Archive | 2011
Michael J. Hadd; Mark W. Holladay; Eduardo Setti
Archive | 2011
Mark W. Holladay; Eduardo Setti
Archive | 2010
Gang Liu; Qi Chao; Michael J. Hadd; Mark W. Holladay; Sunny Abraham; Eduardo Setti
Archive | 2010
Sunny Abraham; Qi Chao; Michael J. Hadd; Mark W. Holladay; Gang Liu; Eduardo Setti
