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Dive into the research topics where Ehab Khalil is active.

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Featured researches published by Ehab Khalil.


Tetrahedron Letters | 1996

An efficient and high yield method for the N-tert-butoxycarbonyl protection of sterically hindered amino acids

Ehab Khalil; Nalin L. Subasinghe; Rodney L. Johnson

Abstract An improved method for the N - tert -butoxycarbonyl protection of the amino functionality of α-alkylated prolines and other sterically hindered α,α-disubstituted amino acids has been developed in which the lipophilic base tetramethylammonium hydroxide is used to solubilize the otherwise insoluble zwitterionic amino acid in acetonitrile, thereby obviating the need for an aqueous medium.


Archive | 2006

Triazolopyridazines as tyrosine kinase modulators

Tianbao Lu; Richard S. Alexander; Richard W. Connors; Maxwell D. Cummings; Robert A. Galemmo; Heather Rae Hufnagel; Dana L. Johnson; Ehab Khalil; Kristi Leonard; Thomas P. Markotan; Anna C. Maroney; Jan L. Sechler; Jeremy M. Travins; Robert W. Tuman


Journal of Medicinal Chemistry | 1999

Design, synthesis, and dopamine receptor modulating activity of spiro bicyclic peptidomimetics of L-prolyl-L-leucyl-glycinamide.

Ehab Khalil; William H. Ojala; Ashish Pradhan; Venugopalan D. Nair; William B. Gleason; Ram K. Mishra; Rodney L. Johnson


Archive | 2003

Thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions

Nalin L. Subasinghe; Ehab Khalil; Kristi Leonard; Farah Ali; Heather Rae Hufnagel; Jeremy M. Travins; Shelley K. Ballentine; Kenneth T. Wilson; Maxwell D. Cummings; Wenxi Pan; Joan Gushue; Sanath K. Meegalla; Mark Wall; Jinsheng Chen; M. Jonathan Rudolph; Hui Huang


Bioorganic & Medicinal Chemistry Letters | 2004

A novel series of potent and selective small molecule inhibitors of the complement component C1s.

Nalin L. Subasinghe; Farah Ali; Carl R. Illig; M. Jonathan Rudolph; Scott I. Klein; Ehab Khalil; Richard Soll; Roger F. Bone; John Spurlino; Renee L. DesJarlais; Carl Crysler; Maxwell D. Cummings; Philip E. Morris; John M. Kilpatrick; Y. Sudhakara Babu


Archive | 2004

CONJUGATED COMPLEMENT CASCADE INHIBITORS

Nalin S. Subasinghe; Ehab Khalil; Farah Ali; Heather Rae Hufnagel; Shelley K. Ballentine; Jeremy M. Travins; Kristi Leonard; Roger F. Bone


Journal of Medicinal Chemistry | 1999

Synthesis and dopamine receptor modulating activity of substituted bicyclic thiazolidine lactam peptidomimetics of L-prolyl-L-leucyl-glycinamide.

Ehab Khalil; Ashish Pradhan; William H. Ojala; William B. Gleason; Ram K. Mishra; Rodney L. Johnson


Tetrahedron Letters | 1997

STEREOSPECIFIC SYNTHESIS OF 2-SUBSTITUTED BICYCLIC THIAZOLIDINE LACTAMS

Nalin L. Subasinghe; Ehab Khalil; Rodney L. Johnson


Archive | 2008

Triazolopiridazinas como moduladores de tirosina cinasas

Tianbao Lu; Richard S. Alexander; Richard W. Connors; Maxwell D. Cummings; Robert A. Galemmo; Heather Rae Hufnagel; Dana L. Johnson; Ehab Khalil; Kristi Leonard; Thomas P. Markotan; Anna C. Maroney; Jan L. Sechler; Jeremy M. Travins; Robert W. Tuman


Archive | 2007

TRIAZOLOPIRIDAZINAS COMO MODULADORES DE QUINASA

Tiambao Lu; Richard S. Alexander; Richard W. Connors; Maxwell D. Cummings; Robert A. Galemmo; Heather Rae Hufnagel; Dana L. Johnson; Ehab Khalil; Kristi Leonard; Thomas P. Markotan; Anna C. Maroney; Jan L. Sechler; Jeremy M. Travins; Robert W. Tuman

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Mark Wall

Pennsylvania State University

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