Emir Yüzbaşıoğlu

Effects of folk medicinal plant extract Ankaferd Blood Stopper® on early bone healing

Objective Several haemostatic agents are available for clinical use. Ankaferd Blood Stopper® (ABS), a mixture of five medicinal plant extracts, has been used historically as a haemostatic agent. The aim of this in vivo study was to investigate the effects of ABS on early bone healing using a rat tibia defect model. Material and Methods Sixteen male Wistar rats were randomized into two groups of 8 animals each. After deep anesthesia with ketamine, bone defects (3 mm diameter and 2 mm deep) were created in the right and left tibiae of all animals and either treated with 1 cc of ABS (Group 1) or left untreated (Group 2; control). Surgical areas were closed primarily. The animals were sacrificed on the 7th postoperative day and bone samples were collected from the tibias. The samples were examined histopathologically for infection, necrosis, fibrosis, new bone formation and foreign body reaction. The histomorphometric results were analyzed statistically by the chi square test, with the level of significance set at p<0.05. Results Significant differences were found in both groups in terms of inflammation, necrosis and new bone formation (p=0.001, p=0.0001, p=0.001). No foreign body reaction was observed in the experimental group. ABS application decreased fibrosis in the experimental group, but there were no statistically significant differences from the control group. Conclusions Histopathologically, it was observed that the application of ABS decreased the occurrence of inflammation and necrosis, while increasing new bone formation in early bone healing period. Further in vitro and in vivo studies are necessary for evaluating the benefits and possible adverse effects of the application of this herbal product on wound healing.

The Effect of Finishing and Polishing Techniques on the Surface Roughness and the Color of Nanocomposite Resin Restorative Materials.

BACKGROUND Rough, poorly polished surfaces contribute to staining, plaque accumulation, gingival irritation and recurrent caries. Finishing and polishing techniques are critical factors contributing to the longevity of the direct composite resin restorations. OBJECTIVES The aim of this in vitro study was to evaluate the effects of finishing and polishing systems on surface roughness of six nanocomposite restorative resins. MATERIAL AND METHODS Thirty specimens of each restorative material (n=180) were placed in a teflon mould (6 mm in diameter and 3 mm in depth) and cured with a LED curing unit. Six specimens from each of restorative material were randomly assigned to four groups for finishing and polishing (carbide burs, diamond burs, aluminium oxide discs, silicon rubber polisher) techniques. Mylar strip formed specimens were served as control group. After finishing and polishing procedures surface roughness was evaluated by a profilometer. The data was analyzed by 2-way analysis of variance and the Tukey HSD test (α=0.05). RESULTS Significant differences were found between the groups in terms roughness (p<0.001). The control group and aluminium oxide discs group had the lowest Ra values and were significantly different from other groups (p<0.001). The roughest surface was obtained with diamond burs followed by silicon rubbers and carbide burs. Overall, the smoothest surfaces were obtained with the use the complete sequence of aluminum oxide discs. CONCLUSIONS In areas that could not be reached by the aluminum oxide discs, the carbide burs produced satisfactory surface smoothness for the nanocomposite restorative materials. Although mylar matrix strip formed surfaces presents lower surface roughness values, recountouring and polishing of resin restorations are often required in clinical situations. Aluminium oxide discs and carbide finishing burs are suitable for finishing and polishing procedures for nanocomposite restorative resins.

Multidisciplinary approach for the rehabilitation of central giant cell granuloma: A clinical report

The central giant cell granuloma (CGCG) is benign, nonodontogenic, and intraosseous lesion of the jaw. Aggressive subtypes of CGCG have a tendency to recur after excision and require wide resection that leads to major defects in the jaw. In this case report a patient who had severe mandibular bony deficiency as a result of excision of aggressive CGCG, orthodontic, and prosthetic treatment was described. The defect was reconstructed with iliac bone graft. Four years later vertical distraction osteogenesis was performed on the grafted mandible in order to obtain a satisfactory bony height of mandibular ridge. After healing period three endosseous dental implants were placed to grafted region. Because of pubertal growth stage, a hybrid removable denture was constructed. The construction of a hybrid removable denture markedly improved the patients speech, mastication, and appearance. After pubertal growth stage, a fixed partial denture construction was planned and future parts of treatment procedures were described to the patient. Distraction osteogenesis and endosseous dental implants can be a good alternative method for the unsatisfactory reconstructions of mandibular deficiencies.

Reverse activated hyrax pressure appliance for treatment of a keloid located at auricula helix.

Keloids are considered aberrations of the wound healing process, and various treatment regimens are described depending on the morphology and size of the lesion. Compression therapy using custom-made pressure clips or splints is widely used for the treatment of keloids. The most common complication of this therapy is ulceration due to excessive soft tissue pressure, resulting in delays and prolonged treatment time. This article describes the fabrication of a custom-made pressure appliance for the treatment of a keloid located at the auricle helix. The pressure appliance can be modified to fit the auricle helix and covers the area needing pressure.

Color match of a feldspathic ceramic CAD-CAM material for ultrathin laminate veneers as a function of substrate shade, restoration color, and thickness

Statement of problem. The final color of a ceramic restoration, especially an ultrathin veneer, is important, but selecting the correct shade is difficult because the substrate can affect the final color of the restoration. Purpose. The purpose of this in vitro study was to investigate the effect of substrate shade and thickness on the final color of ultrathin laminate veneers milled from feldspathic ceramic and to present a straightforward methodology with which a clinician can visualize the effects of substrate color, ceramic thickness, and prefabricated computer‐aided design and computer‐aided manufacturing (CAD‐CAM) block color on the final color of the restoration. Material and methods. All specimens were fabricated by slicing CAD‐CAM feldspathic ceramic material with a precision cutter into 12×10‐mm slices of approximately 0.35, 0.55, 0.75, and 1.55 mm in thickness with 10 different colors (0M1‐1M1‐1M2‐2M1‐2M2‐2M3‐3M1‐3M2‐3M3‐4M1). As a background substrate, composite resin disks (12×10×2 mm) were fabricated with different shades (0M1 S, 1M1 S, 2M3 S, 3M2 S, 4M3 S, 5M3 S). The CIELab values of the polished surfaces of each specimen were measured on a background (white or simulated foundation) with a spectrophotometer by a single experienced operator, and color differences (&Dgr;E) were calculated. Mean ±SD values were calculated and subjected to ANOVA with 2 variables (substrate and ceramic color) (&agr;=.05). Results. Combinations of a lighter substrate shade and a lighter value ceramic restoration and of a darker substrate shade and darker value ceramic restoration only changed the final color of the restoration minimally. Conclusions. The final color of a dental restoration is affected by the thickness of the restoration, the substrate color, and the ceramic color. Lighter and darker substrate colors show more color changes, and thin veneers cannot mask the substrate color.