Seda Cengiz

Melatonin and oral cavity

While initially the oral cavity was considered to be mainly a source of various bacteria, their toxins and antigens, recent studies showed that it may also be a location of oxidative stress and periodontal inflammation. Accordingly, this paper focuses on the involvement of melatonin in oxidative stress diseases of oral cavity as well as on potential therapeutic implications of melatonin in dental disorders. Melatonin has immunomodulatory and antioxidant activities, stimulates the proliferation of collagen and osseous tissue, and acts as a protector against cellular degeneration associated with aging and toxin exposure. Arising out of its antioxidant actions, melatonin protects against inflammatory processes and cellular damage caused by the toxic derivates of oxygen. As a result of these actions, melatonin may be useful as a coadjuvant in the treatment of certain conditions of the oral cavity. However, the most important effect of melatonin seems to result from its potent antioxidant, immunomodulatory, protective, and anticancer properties. Thus, melatonin could be used therapeutically for instance, locally, in the oral cavity damage of mechanical, bacterial, fungal, or viral origin, in postsurgical wounds caused by tooth extractions and other oral surgeries. Additionally, it can help bone formation in various autoimmunological disorders such as Sjorgen syndrome, in periodontal diseases, in toxic effects of dental materials, in dental implants, and in oral cancers.

Dental erosion caused by gastroesophageal reflux disease: a case report

IntroductionChronic regurgitation of gastric acids in patients with gastroesophageal reflux disease may cause dental erosion, which can lead in combination with attrition or bruxism to extensive loss of coronal tooth tissue.Case presentationThis clinical report describes treatment of severe tooth wear of a gastroesophageal reflux disease patient who is 54-year-old Turkish male patient. After his medical treatment, severe tooth wear, bruxism and decreased vertical dimensions were determined. The vertical dimension was re-established and maxillary and mandibular anterior and posterior teeth were prepared for metal-ceramic restorations. Metal-ceramic fixed partial dentures were fabricated as full mouth restorations for both maxillary and mandibular arches because of splinting all teeth. And then maxillary stabilization splint was fabricated for his bruxism history.ConclusionSignificant loss of coronal tooth structure must taken into consideration. Gastroesophageal reflux disease by itself or in combination with attrition, abrasion or bruxism may be responsible for the loss. An extensive diagnostic evaluation is essential for the medical and dental effects of the problem.

Color match of a feldspathic ceramic CAD-CAM material for ultrathin laminate veneers as a function of substrate shade, restoration color, and thickness

Statement of problem. The final color of a ceramic restoration, especially an ultrathin veneer, is important, but selecting the correct shade is difficult because the substrate can affect the final color of the restoration. Purpose. The purpose of this in vitro study was to investigate the effect of substrate shade and thickness on the final color of ultrathin laminate veneers milled from feldspathic ceramic and to present a straightforward methodology with which a clinician can visualize the effects of substrate color, ceramic thickness, and prefabricated computer‐aided design and computer‐aided manufacturing (CAD‐CAM) block color on the final color of the restoration. Material and methods. All specimens were fabricated by slicing CAD‐CAM feldspathic ceramic material with a precision cutter into 12×10‐mm slices of approximately 0.35, 0.55, 0.75, and 1.55 mm in thickness with 10 different colors (0M1‐1M1‐1M2‐2M1‐2M2‐2M3‐3M1‐3M2‐3M3‐4M1). As a background substrate, composite resin disks (12×10×2 mm) were fabricated with different shades (0M1 S, 1M1 S, 2M3 S, 3M2 S, 4M3 S, 5M3 S). The CIELab values of the polished surfaces of each specimen were measured on a background (white or simulated foundation) with a spectrophotometer by a single experienced operator, and color differences (&Dgr;E) were calculated. Mean ±SD values were calculated and subjected to ANOVA with 2 variables (substrate and ceramic color) (&agr;=.05). Results. Combinations of a lighter substrate shade and a lighter value ceramic restoration and of a darker substrate shade and darker value ceramic restoration only changed the final color of the restoration minimally. Conclusions. The final color of a dental restoration is affected by the thickness of the restoration, the substrate color, and the ceramic color. Lighter and darker substrate colors show more color changes, and thin veneers cannot mask the substrate color.

Effect of Er,Cr:YSGG laser surface conditioning on the adhesion of fiber- reinforced composite and zirconia intraradicular posts to the root dentin

Abstract This study evaluated the influence of Er,Cr:YSGG laser surface conditioning on push-out bond strength of different root posts to the root dentin. Extracted (N = 27, n = 9 per group) and endodontically treated human mandibular premolars were prepared to receive the posts. Three types of posts, namely quartz fiber (D), glass fiber (S), and zirconium dioxide post (C) were luted with resin cement. The posts were randomly assigned to one of the surface conditioning method: (a) No conditioning, control (L0), (b) Er,Cr:YSGG laser at 175 mJ, 3.5 W for 60 s (L1), and (c) at 225 mJ, 4.5 W for 60 s, with 60 μs pulse duration and repetition rate was 20 Hz (L2) irradiation. Six sections (two coronal, two middle, and two apical) were made in each tooth yielding to 1 mm thick specimens. The specimens were stored in distilled water at 37 °C for 24 h and push-out bond strength (MPa) was tested in a Universal Testing Machine (1 mm/min). Data were analyzed using Kruskall–Wallis and Dunns`s post hoc tests (α = 0.05). In group D, both laser treated groups (L1:16.16 ± 19.89; L2:8.24 ± 9.26) presented significantly less bond strength compared to control group (L0:28.3 ± 16.8) (p < 0.001). Mean push-out bond strength values did not significantly differ according to the root segments (coronal, middle, and apical) (p = 0.106). Application of Er,Cr:YSGG laser, with the parameters tested, did not increase the bond strength of zirconium glass fiber and zirconium oxide posts. Laser surface conditioning decreased the bond strength of quartz fiber posts in the root canal.

Outcome of Implants in Kidney Transplant Patient Undergoing Immunosuppressive Therapy: Case Report

Corresponding Adress/İletişim Adresi: Murat İnanç CENGİZ Bülent Ecevit Üniversitesi Diş Hekimliği Fakültesi, Periodontoloji Anabilim Dalı, Zonguldak, Turkey E-mail/E-posta: dtinanc@mynet.com ABSTRACT Since the beginning of oral implant surgery, it has been recommended to exclude certain patients with systemic health problems from implant therapy. Although many studies have been done about the effect of systemic disease like diabetes and osteoporosis on implant success but there wasn’t enough data about the effect of organ transplantation and immunosupresive therapy on implant success in the literature. As the success rate of organ transplantations increased, the number of patients on immunosupressive treatment increased. It has been reported in the literature that organ transplant patients undergoing immunosuppressive therapy may experience periodontal side-effects such as gingival overgrowth and implant failure. In our case 10 year of implant success was examined on the patient who are exposed to kidney transplantation 8 years ago and who takes cortisone and immunosupressive.