Is this you? Create Your Porfile
Avatar

Eric Mull

Bristol-Myers Squibb

Network

Latest external collaboration on country level. Dive into details by clicking on the dots.

Explore More

Hotspot

Dive into the research topics where Eric Mull is active.

Explore More

Publication

Featured researches published by Eric Mull.

Bioorganic & Medicinal Chemistry Letters | 2017

Functionalized triazines as potent HCV entry inhibitors

Eric Mull; Li-Qiang Sun; Qian Zhao; Betsy J. Eggers; Kevin A. Pokornowski; Guangzhi Zhai; Ramkumar Rajamani; Susan Jenkins; Melissa A. Kramer; Ying-Kai Wang; Hua Fang; Daniel J. Tenney; Carl J. Baldick; Mark Cockett; Nicholas A. Meanwell; Paul Michael Scola

A series of potent and novel acylsulfonamide-bearing triazines were synthesized and the structure-activity relationships (SARs) as HCV entry inhibitors were evaluated. This acylsulfonamide series was derived from an early lead, 4-(4-(1-(4-chlorophenyl)cyclopropylamino)-6-(2,2,2-trifluoroethoxy)-1,3,5-triazin-2-ylamino)benzoic acid wherein the carboxylic acid was replaced with an acylsulfonamide moiety. This structural modification provided a class of compounds which projected an additional vector off the terminus of the acylsulfonamide functionality as a means to drive activity. This effort led to the discovery of potent analogues within this series that demonstrated sub-nanomolar EC50 values in the HCV pseudotype particle (HCVpp) assay.

Archive | 2014

MACROCYCLIC INHIBITORS OF THE PD-1/PD-L1 AND CD80(B7-1)/PD-L1 PROTEIN/PROTEIN INTERACTIONS

Michael M. Miller; Claudio Mapelli; Martin Patrick Allen; Michael S. Bowsher; Kenneth M. Boy; Eric P. Gillis; David R. Langley; Eric Mull; Maude A Poirier; Nishith Sanghvi; Li-Qiang Sun; Daniel J. Tenney; Kap-Sun Yeung; Juliang Zhu; Patrick C. Reid; Paul Michael Scola

Archive | 2016

MACROCYCLIC PEPTIDES USEFUL AS IMMUNOMODULATORS

Kevin W. Gillman; Jason Goodrich; Kenneth M. Boy; Yunhui Zhang; Claudio Mapelli; Michael A. Poss; Li-Qiang Sun; Qian Zhao; Eric Mull; Eric P. Gillis; Paul Michael Scola; David R. Langley

Archive | 2014

MACROCYCLIC COMPOUNDS AS HCV ENTRY INHIBITORS

Tao Wang; Zhongxing Zhang; Zhiwei Yin; Li-Qiang Sun; Eric Mull; Qian Zhao; Paul Michael Scola

Archive | 2017

PÉPTIDOS MACROCÍCLICOS QUE INHIBEN INTERACCIONES PROTEÍNA / PROTEÍNA DE PROTEÍNA DE LA MUERTE (PD-1 / PD-L1) E INHIBEN INTERACCIÓN CD80 / PD-L1

Paul Michael Scola; Eric Mull; Martin Patrick Allen; Qian Zhao; Li Sun; Eric P. Gillis; Claudio Mapelli

Archive | 2017

MACROCYCLIC INHIBITORS OF THE PD-1/PD-L1 AND CD80(B7-1)/PD-L1 PROTEIN/PROTEIN INTERACTIONS PD-1/PD-L1 CD80(B7-1)/PD-L1 /

Michael M. Miller; Claudio Mapelli; Martin Patrick Allen; Michael S. Bowsher; Kenneth M. Boy; Eric P. Gillis; David R. Langley; Eric Mull; Maude A Poirier; Nishith Sanghvi; Li-Qiang Sun; Daniel J. Tenney; Kap-Sun Yeung; Juliang Zhu; Patrick C. Reid; Paul Michael Scola

Archive | 2017

Peptidos macrocíclicos útiles como inmunomoduladores

Kevin W. Gillman; Jason Goodrich; Kenneth M. Boy; Yunhui Zhang; Claudio Mapelli; Michael A. Poss; Li-Quiang Sun; Quian Zhao; Eric Mull; Eric P. Gillis; Paul Michael Scola; David R. Langley; Nicholas A. Meanwell

Archive | 2017

9-methyl substituted hexadecahydrocyclopropa(e)pyrrolo(1,2-a)(1,4)diazacyclopentadecinyl carbamate derivatives as non-structural 3 (ns3) protease inhibitors for the treatment of hepatitis c virus infections

Li-Qiang Sun; Eric Mull; Eric P. Gillis; Michael S. Bowsher; Qian Zhao; Kishore V. Renduchintala; Kandhasamy Sarkunam; Pulicharla Nagalakshmi; Suresh P V K Babu; Paul Michael Scola

Archive | 2016

INHIBIDORES MACROCÍCLICOS DE LAS INTERACCIONES: PROTEÍNA DE LA MUERTE PROGRAMADA (PD-1) CON SU LIGANDO (PD-L1) [INTERACCIÓN PD-1 / PD-L1] Y DEL CÚMULO DE DIFERENCIACIÓN 80 (CD80) CONOCIDO TAMBIÉN COMO PROTEÍNA B7-1 CON EL LIGANDO 1 DE LA PROTEÍNA DE LA MUERTE PROGRAMADA (PD-L1) [INTERACCIÓN CD80 O B7-1 / PD-L1]

Michael M. Miller; David R. Langley; Nishith Sanghvi; Li Sun; Qian Qiang Zhao; Kap Yeung; Kevin W. Gillman; Katharine A. Grant-Young; Paul Michael Scola; Juliang Zhu; Eric P. Gillis; Daniel J. Tenney; Eric Mull; Maude A Poirier; Claudio Mapelli; Martin Patrick Allen; Michael S. Bowsher

Archive | 2016

PÉPTIDOS MACROCÍCLICOS COMO INHIBIDORES DE LAS INTERACCIONES ENTRE LAS PROTEÍNAS PD-1/PD-L1 Y CD80/PD-L1 Y SUS FUNCIONES INMUNOMODULADORAS

Gillman Kevin W; Jason Goodrich; Yunhui Zhang; Poss Michael A; Qian Zhao; Claudio Mapelli; Boy Kenneth M; Gillis Eric P; Langley David R; Eric Mull; Sun Li-Qiang; Scola Paul Michael

Explore More

Collaboration

Dive into the Eric Mull's collaboration.

Top Co-Authors
Avatar

Paul Michael Scola

Bristol-Myers Squibb

View shared research outputs
Top Co-Authors
Avatar

Claudio Mapelli

Bristol-Myers Squibb

View shared research outputs
Top Co-Authors
Avatar

Eric P. Gillis

Bristol-Myers Squibb

View shared research outputs
Top Co-Authors
Avatar

David R. Langley

Bristol-Myers Squibb

View shared research outputs
Top Co-Authors
Avatar

Li-Qiang Sun

Bristol-Myers Squibb

View shared research outputs
Top Co-Authors
Avatar

Daniel J. Tenney

Bristol-Myers Squibb

View shared research outputs
Top Co-Authors
Avatar

Juliang Zhu

Bristol-Myers Squibb

View shared research outputs
Top Co-Authors
Avatar

Kenneth M. Boy

Bristol-Myers Squibb

View shared research outputs
Top Co-Authors
Avatar

Martin Patrick Allen

Bristol-Myers Squibb

View shared research outputs
Top Co-Authors
Avatar

Michael S. Bowsher

Bristol-Myers Squibb

View shared research outputs
Explore More
Researchain Logo
Decentralizing Knowledge