Euis Julaeha

Flavonoids from the Fresh Leaves of Kalanchoe tomentosa (Crassulaceae)

Flavonoids compounds such as kaempferol (1), kaempferol-3-O- -D-glucopyranoside or astragalin (2) and kaempferol-3-O- -L-rhamnoside or afzelin (3) have been isolated from the fresh leaves of Kalanchoe tomentosa (Crassulaceae). The chemical structure of isolated compounds 1-3 were identified by spectroscopic evidences and comparison with those compound previously reported. Compounds 1-3 showed cytotoxic activity against P-388 murine leukimia cells with IC50 values of 51.8, � 100 and 3.32 μg/mL, respectively.

Meranzin hydrate from Muraya paniculata

The coumarin ring system in the title compound, C15H18O5 [IUPAC name: 8-(2,3-dihydroxy-3-methylbutyl)-7-methoxy-2H-1-benzopyran-2-one], isolated from Muraya paniculata, is planar (r.m.s. deviation 0.017 Å). In the crystal, the two hydroxy groups are involved in O—H⋯O hydrogen bonding with adjacent molecules, forming a sheet structure.

ANTIBACTERIAL TRITERPENOIDS FROM THE BARKS AND LEAVES OF Lansium domesticum Corr cv. Kokossan (MELIACEAE)

Three triterpenoid compounds, 8,14-secogammacera-7,14-dien-3,21-dione (1), 8,14-secogammacera-7en-14-hydroxy-3,21-dione (2) and 9,19-cyclolanost-24-en-3-one, 21,23 epoxy-21,22-dihydroxy (21R, 22S, 23S) (3) has been isolated from the barks and leaves of L. domesticum cv kokossan (Meliaceae). The chemical structures of compounds 1-3 were identified with spectroscopic data, including UV, IR, NMR and MS, and their spectra were compared with previously reported spectra data. Compound 1, 2 were evaluated for their antibacterial effects against Escherichia coli and Bacillus ereus. Compound 3 was evaluated for their antibacterial effects against Escherichia coli and Enterococcus feacalis. Compound 1 showed the inhibition zone values of 7.5 dan 8.0 mm at 500 and 1000 ppm against Escherichia coli, whereas for Bacillus cereus it was inactive. Compound 2 showed the inhibition zone values of 8.0 dan 10.0 mm at concentrations of 500 and 1000 ppm against Escherichia coli, whereas for Bacillus cereus it was inactive. Compound 3 showed the inhibition zone values of 3.67 mm, 3.17 mm, 2.32 mm at concentrations of 10000, 5000 and 1000 ppm respectively against Escherichia coli, whereas for Enterococcus feacalis it was inactive.