Feray Aydogan

Synthesis of New Pyrazolothiazole Derivatives from 4-Thiazolidinones

The synthesis of new 2,3,5,6-aryl substituted tetrahydro-2H-pyrazolo[3,4-d]- thiazoles 4a-j as potential biologically active compounds by the cyclocondensation of phenyl hydrazine with new 5-arylidene derivatives 2a-j of 2,3-disubstituted-1,3- thiazolidin-4-ones 1a-e is reported.

Clauson Kaas Pyrrole Synthesis Catalyzed by Acidic Ionic Liquid under Microwave Irradiation

A new procedure to synthesize the N-substituted pyrrole derivatives by Clauson Kaas reaction catalyzed by acidic ionic liquid under microwave irradiation was developed. This procedure provides several advantages such as high yield, clean product formation, and short reaction time.

No-Aqueous Titrations: Potentiometric Titration of Some Primary Amines

Potentiometrie titrations of some primary amines; 1-aminobutane, 1aminopropane and 3-amino-l-phenylbutane were carried out with hydrochloric acid in toluene solvent. The same titrations were done with hydrochloric acid in methanol solvent to show the effect of amphiprotic solvent in the titrations with hydrochloric acid. For each weak base, an Sshaped Potentiometrie titration curve was obtained. As a result, toluene, which is an aprotic inert solvent, is a suitable solvent for titrating some of the weak bases potentiometrically.

New and effective proline-based catalysts for asymmetric aldol reaction in water

ABSTRACT New proline diamide organocatalysts with Pro-Phe peptide bonds were synthesized and their catalytic activities in asymmetric direct aldol reactions of aliphatic ketones with aromatic aldehydes were investigated. Catalyst 6a showed good enantioselectivity at 0 °C in the presence of p-nitrobenzoic acid as cocatalyst in water. GRAPHICAL ABSTRACT

Potentiometrie Titration of P-Anisidine and P-Toluidine in Non-Aqueous Media

Potentiometrie titrations of p-anisidine and p-toluidine were carried out with hydrochloric acid in toluene solvent. The same titrations were done with hydrochloric acid in methanol solvent to show the effect of amphiprotic solvent in the titrations with hydrochloric acid. For each weak base, an Sshaped Potentiometrie titration curve was obtained. As a result, toluene, which is an aprotic inert solvent, is a suitable solvent for titrating some of the weak bases potcntiometrically.

A Potentiometric Investigation of Primary Amines in Non-aqueous Media

Titration of weak bases in non-aqueous solvents can provide valu- able information about these weak bases. Some primary amines; 1-aminobutane, 1-aminopropane, 2-aminoheptane, aminocyclohexane, 3-amino-1-phenylbutane were titrated with hydrochloric acid in toluene solvent. All the primary amines gave very well-shaped potentiometric titration curves. The same titrations were done with hydrochloric acid in methanol solvent to show the effect of amphiprotic solvent in the titrations with hydrochloric acid. As a result, toluene is a suitable solvent for titrating some of the primary amines potentiometrically with hydrochloric acid.

The Biological Activities of New Heterocylic Compounds Containing Nitrogen and Sulphur

Oxadiazole derivatives which belong to an important group of heterocyclic compounds have been subject of extensive study in the recent past. Numerous reports have appeared which highlight their chemistry and. use1–3. Diverse biological activities such as antituberculostatic, antiinflamatory, analgesic, antipyretic, anticonvulsant, etc. have been found to be associated with oxadiazole derivatives4’5. Because of this reason we aimed to synthesize various 1,3,4-oxadiazole-2-thione derivatives to make remarkable contributions to this class of heterocyclic compounds. Here, we report the synthesis and characterization of some 5-alkyl substituted 1,3,4oxadiazole-2-thiones (3a-e) and 5-alkyl substituted 3-(2,4-dimethylphenyl)1,3,4-oxadiazole-2-thiones (4a-d) by using the synthetic procedure based on the ring closure reactions of appropriate acid hydrazides with carbon disulphide6. We also have synthesized some bis-Mannich bases by the reaction of 3a-e with benzaldehyde and benzidine.

4,6-Di­methyl-2-(o-tolyl­imino­methyl)­quinoline

The molecule of the title compound, C19H18N2, is not planar. The dihedral angle between the quinoline and phenyl rings is 118.5 (1)°.