Fernando José de Nóbrega

Atuação multiprofissional e a saúde mental de gestantes

OBJECTIVE To identify non-psychotic affective disorders in pregnant women, to intervene by means of psychoprophylactic groups, and to evaluate possible alterations following intervention. METHODS One-hundred and three pregnant women (71 adults and 32 adolescents) were seen at a community program in the Paraisópolis neighborhood in the city of Sao Paulo, southeastern Brazil. We used the following instruments: Self Reporting Questionnaire and Beck Depression Inventory. Ten weekly two-hour meetings were held, addressing the link between mother and fetus and subjects related to mother and child, and answering mothers doubts. We used the chi-squared test (chi2) to compare mental health before and after the intervention, with a significance level of p<0.05. RESULTS Affective disorders were found in 45 pregnant women (43.7%) before the intervention and in 23 (22.3%) after the intervention. The impact of the intervention on affective disorders was statistically significant (p=0.001). Twenty-one women (20.4%) showed depression before the intervention, and 13 (12.6%) after the intervention, a non-significant difference (p=0.133). CONCLUSIONS Multiprofessional care can prevent, detect, and treat affective disorders during pregnancy in both adults and adolescents.

Nutritional gains of underprivileged children attending a day care center in S.Paulo City, Brazil: a nine month follow-up study

The efficacy of a well-operated day care center in providing better nutrition to poor children in Brazil was assessed. We collected data for 9 months from 180 under-five children attending a day care center located in a slum. Every working day each child received at least 100% of the age-group recommended dietary allowances plus iron fortified milk and, every six months, treatment for helminth infections. Statistical analyses were restricted to the 168 children (93%) who had measurements from at least five months. As outcome variables, weight-for-height, height-for-age, and weight-for-age Z scores were dichotomized so that a Z score < -1 indicated a child was at risk of malnutrition. We examined the proportion of children at nutritional risk in each month and used multivariate statistical techniques to adjust for confounding and to account for intra-subject correlation. The percentage of children at nutritional risk decreased over time, from 10.1% to 3.4% for weight for height, 29.8% to 15.2 % for weight for age, and from 50.0% to 44.8% for height for age. Most of the reduction took place between the third and fourth months of enrollment. The correlated data models for the three dichotomized outcomes showed a two to three-fold reduction in the occurrence of wasting and underweight. We concluded that attendance to well-operated daycare protects against nutritional risk, and approximately four months are required for a benefit to be seen.

Insulin resistance in obese children and adolescents

OBJECTIVE To evaluate the presence of insulin resistance and its association with other metabolic abnormalities in obese children and adolescents. METHODS Retrospective study of 220 children and adolescents aged 5-14 years. Anthropometric measurements were performed (weight, height, and waist circumference) and clinical (gender, age, pubertal stage, and degree of obesity) and biochemical (glucose, insulin, total cholesterol, and fractions, triglycerides) data were analyzed. Insulin resistance was identified by the homeostasis model assessment for insulin resistance (HOMA-IR) index. The analysis of the differences between the variables of interest and the HOMA-IR quartiles was performed by ANOVA or Kruskal-Wallis tests. RESULTS Insulin resistance was diagnosed in 33.20% of the sample. It was associated with low levels of high-density lipoprotein cholesterol (HDL-C; p=0.044), waist circumference measurement (p=0.030), and the set of clinical and metabolic (p=0.000) alterations. Insulin-resistant individuals had higher mean age (p=0.000), body mass index (BMI; p=0.000), abdominal circumference (p=0.000), median triglycerides (p=0.001), total cholesterol (p≤0.042), and low-density lipoprotein cholesterol (LDL-C; p≤0.027); and lower HDL-C levels (p=0.005). There was an increase in mean BMI (p=0.000), abdominal circumference (p=0.000), and median triglycerides (p=0.002) as the values of HOMA -IR increased, with the exception of HDL-C, which decreased (p=0.001). Those with the highest number of simultaneous alterations were between the second and third quartiles of the HOMA-IR index (p=0.000). CONCLUSION The results confirmed that insulin resistance is present in many obese children and adolescents, and that this condition is associated with alterations that represent an increased risk for developing metabolic disorders in adulthood.

Tratamento da desnutrição em crianças hospitalizadas em São Paulo

AIM:To study anthropometric development, nutritional support and mortality rate of malnourished children hospitalized in a referral center METHODS: In a retrospective study we surveyed 98 hospitalized malnourished children (ZW<-2) with no chronic disease. Data collected was: birth weight, gestational age, length of exclusive breast feeding, diagnosis at admission, formula used (type, delivery route and feeding tolerance) and length of stay. Weight and height were controlled at admission and discharge. To classify and evaluate nutritional rehabilitation we used the Z-score: weight-for-age (ZW), height-for-age (ZH), weight-for-height (ZW/H). The nutritional therapy used was based on the World Health Organization (WHO) guidelines, with minor modifications. All chosen formulas were industrialized: lactose-free polymeric formula (PLF) for children with diarrhea, low lactose polymeric formula (PLL) for children without diarrhea and cows milk hydrolysate (CMH) for sepsis or chronic diarrhea. At the rehabilitation phase, all children were given the PLL formula. STATISTICAL ANALYSIS: Students t and chi-square tests. RESULTS: The median of age and length of stay were 9.8 months and 17 days, respectively and the mortality rate was of 2%. Diarrhea and/or pneumonia were diagnosed at admission in 81.6% of the children. An improvement of 17.3 % ZW, 82.7 % ZH and 92.2 % ZW/H was observed. PLF was more frequently given at admission (47.4%) while CMH was given to only 7.4% of the children. Twenty-four percent of the children were tube fed and 5.1 % received parenteral nutrition. Tolerance of the initial formula was considered good in 66.7% of cases. CONCLUSIONS: The WHO guidelines were effective in the nutritional therapy of severely malnourished hospitalized children, resulting in good nutritional rehabilitation with low mortality rates.

Anemia in low-income exclusively breastfed infants.

OBJECTIVE To verify the behavior of hemoglobin levels and anemia prevalence in full term infants, aged 3 to 6 months and on exclusive breastfeeding. METHODS A cross-sectional study of 242 infants aged 3 to 6 months with birth weights of more than 2,500 g, on exclusive breastfeeding and monitored by the Program for the Promotion of Infant Growth and Development, part of the Paraisópolis Einstein Community Program. Hemoglobin was assayed by finger prick between the third and sixth months of life. Anemia was defined as Hb < 10.3 g/dL (Saarinen) or Hb < 10 g/dL (Brault-Dubuc) for infants aged 3 to 5 months and as Hb < 11.0 g/dL (WHO) for infants aged 6 months. RESULTS Mean hemoglobin concentration was 11.3 and 11.4 g/dL at 3 and 4 months and 11.2 and 11.1 g/dL at 5 and 6 months, respectively. The percentage of anemic infants varied depending on age and the cutoff adopted, being 11.8, 10.2 and 8.3% at 3, 4 and 5 months, respectively, according to the Brault-Dubuc criteria, and 20.6, 14.8 and 10.4% by the Saarinen criteria. Anemia prevalence at 6 months was 37.5%. CONCLUSIONS Anemia prevalence rates observed among infants aged between 3 and 6 months varied from 8.3 to 37.5%, justifying increased attention on the part of pediatricians to the hemoglobin levels of infants who are on exclusive breastfeeding, come from low-income families and present risk factors for iron deficiency.

Neuropsychology and malnutrition: a study with 7 to 10 years-old children in a poor community

OBJECTIVES: to compare the neuropsychological profile of eutrophic, stunted and chronically malnourished children, and to analyse the role of socio-economic factors on the cognitive development. METHODS: seven to 10 year-old girls and boys from a poor community in Sao Paulo were evaluated: 27 eutrophyc, 31 stunted and 15 chronically malnourished. Neuropsychological evaluation involved cognitive functions not fully assessed in this population, such as working, declarative and non-declarative memories, attention and executive functions. Socio-economic indicators, maternal mental health and the childrens behaviour at school were also evaluated. RESULTS: malnourished children had a lower score on the vocabulary test than the eutrophic and stunted groups (ps<0.05), performed worse in the visuospatial working memory task (p = 0.01), were more anxious than the stunted (p = 0.006), and despite having lower average birth weight than eutrophic children (p = 0.01), only two children as had prenatal malnutrition. Stunted children exhibited no impairment. No differences in socio-economic variables were found among groups. CONCLUSIONS: chronic malnutrition was associated to impairment of expressive speech, visual-spatial short-term memory and increased anxiety. No effects were observed in intellectual abilities, executive functions, verbal working memory, long-term memory, nor in visuoconstructive function. Preservation of the latter cognitive functions can be attributed to adequate environmental conditions and the lack of overall prenatal malnutrition.

Anemia em lactentes de baixa renda em aleitamento materno exclusivo

OBJETIVO:Verificar o comportamento dos valores da hemoglobina e a prevalencia de anemia entre lactentes de termo de 3 a 6 meses de idade em aleitamento materno exclusivo. METODOS: Estudo transversal em 242 lactentes de 3 a 6 meses de idade com peso de nascimento superior a 2.500 g, em aleitamento materno exclusivo e em acompanhamento no Programa de Promocao do Crescimento e Desenvolvimento do Lactente do Programa Einstein na Comunidade de Paraisopolis. A dosagem de hemoglobina foi realizada por meio de puncao digital entre o terceiro e o sexto meses de vida. Adotaram-se os valores de Hb < 10,3 g/dL (Saarinen) e Hb < 10 g/dL (Brault-Dubuc) como criterio de anemia nas idades de 3 a 5 meses e Hb < 11,0 g/dL (OMS) para os lactentes de 6 meses. RESULTADOS: A media da hemoglobina foi de 11,3 e 11,4 g/dL aos 3 e 4 meses, 11,2 e 11,1 g/dL aos 5 e 6 meses, respectivamente. A porcentagem de anemicos variou conforme a idade e o padrao adotado, sendo de 11,8, 10,2 e 8,3% aos 3, 4 e 5 meses, segundo o criterio adotado por Brault-Dubuc, e de 20,6, 14,8 e 10,4%, respectivamente, para o criterio de Saarinen. Aos 6 meses, a prevalencia de anemia foi de 37,5%. CONCLUSOES: Observaram-se prevalencias de anemia variando entre 8,3 e 37,5% nos lactentes do terceiro ao sexto mes de vida, que justificam maior atencao do pediatra em relacao aos niveis de hemoglobina em lactentes em aleitamento materno exclusivo, que pertencam a familias de baixa renda e que apresentem fatores de risco para deficiencia de ferro.

Impact of the application of neurolinguistic programming to mothers of children enrolled in a day care center of a shantytown

CONTEXT Of the members of a family, the mother is without doubt the most important one, which provides justification for including an evaluation of her mental health as one of the variables to be considered as determining factors in each childs level of development. OBJECTIVE To assess the impact of the application of Neurolinguistic Programming (NLP) on child development, home environment and maternal mental health. DESIGN Randomised controlled trial. SETTING The study included children enrolled in the municipal day care center of a shantytown in the City of São Paulo. PARTICIPANTS 45 pairs of mothers and respective children between 18 and 36 months of age. MAIN MEASUREMENTS Childrens development (Bayley scales); home environment variation (HOME); and maternal mental health (SRQ). Comparison between before and after the intervention was made in terms of childrens psychomotor development, home environment and maternal mental health. INTERVENTION Application of the NLP technique to the experimental group and comparison with a control group. 1--Experimental (EG), consisting of 23 children submitted to intervention by NLP; and 2--Control (CG), with 22 children with no intervention. Length of intervention: 15 sessions of NLP. RESULTS 37 children remained in the study (EG = 10, CG = 27). Variations in mental development (OR 1.21, IC 95% 0.0 to 23.08) in their home environment (Wilcoxon): p = 0.96 (before) and p = 0.09 (after); in maternal mental health: p = 0.26, 2 df. CONCLUSIONS There was a trend that indicated positive effects on the home environment from the intervention.

Suplemento artesanal oral: uma proposta para recuperação nutricional de crianças e adolescentes com câncer

Objective The aim of this study was to evaluate the impact of homemade oral supplements on the nutritional recovery of patients with mild or severe malnutrition or at nutritional risk. Methods Eight recipes of homemade oral supplements containing 30% to 35% of the total energy expenditure were proposed. The patients with severe malnutrition (group B) received the oral supplement for 2 weeks and the others for 4 weeks (group A). Oral supplementation with homemade supplements was compared with oral supplementation with store-bought supplements, investigated earlier with a protocol with the same design. Results Homemade oral supplements contain much lower amounts of certain micronutrients but are five times cheaper than store-bought supplements. In group A, 88% of the patients taking homemade oral supplements and 84% of the patients taking store-bought supplements responded positively to supplementation. In group B, 22% of the patients taking homemade oral supplements and 25% of the patients taking store-bought supplements recovered. The difference was not significant. The impact of store-bought supplementation on the triceps skinfold thicknesses and arm circumferences of the patients in group A was greater than that obtained with homemade supplements. In group B, the effect on triceps skinfold thickness was not significant (p=0.16). Patients taking homemade or store-bought oral supplements presented similar protein and energy intakes and improvements in nutritional status. Only the body composition of patients in group A taking store-bought oral supplements was better. Conclusion The results obtained by this study suggest that the therapeutic use of homemade oral supplements is an alternative capable of promoting the nutritional recovery of cancer patients, especially those who cannot afford store-bought supplements.

Avaliação do vínculo mãe-filho e saúde mental de mães de crianças com deficiência intelectual

OBJECTIVE: To verify and evaluate the mother-child bond and mental health of mothers of children with intellectual disabilities. METHODS: A total of 74 mothers of children aged up to 7 years participated. Data collection was made through interviews. Evaluation tools were Mother-Child Bonding Evaluation Protocol and Self-Report Questionnaire. We used statistical analysis χ2 and Student-t tests. A 5%-level of rejection of the null hypothesis was set. RESULTS: There were no significant results between the average maternal ages, between bond and schooling, nor time of marriage and social status. The percentage of low social condition mothers with weak bond were 38.7% and in high condition, 68.8%. CONCLUSION: The occurrence of weak bond is associated with the Self-Report Questionnaire and socio-cultural conditions. That is, mothers with alteration in the Self-Report Questionnaire are more likely to develop mental disorders, weak bond with their children, the same occurring with the mothers in the most privileged social conditions.ABSTRACT Objective: To verify and evaluate the mother-child bond and mental health of mothers of children with intellectual disabilities. Methods: A total of 74 mothers of children aged up to 7 years participated. Data collection was made through interviews. Evaluation tools were Mother-Child Bonding Evaluation Protocol and Self-Report Questionnaire. We used statistical analysis χ2 and Student-t tests. A 5%-level of rejection of the null hypothesis was set. Results: There were no significant results between the average maternal ages, between bond and schooling, nor time of marriage and social status. The percentage of low social condition mothers with weak bond were 38.7% and in high condition, 68.8%. Conclusion: The occurrence of weak bond is associated with the Self-Report Questionnaire and socio-cultural conditions. That is, mothers with alteration in the Self-Report Questionnaire are more likely to develop mental disorders, weak bond with their children, the same occurring with the mothers in the most privileged social conditions.