Gabriel Menichi

A new “one flask” preparation of 2-alkylamino-4-chloroquinazolines from ortho aminobenzonitriles and phosgeniminium salts

Abstract Phosgeniminium salts 7 react easily with ortho amino-benzonitriles 6 to give, selectively and quantitatively the corresponding 2-dialkylamino-4-chloroquinazolines 5 .

A new “one pot” preparation of 2-n,n-dialkylamino-1,3-benzoxazines and naphth[ 1,2-e][ 1,3]oxazines from corresponding ortho hydroxynitriles and phosgeniminium salts

Abstract Phosgeniminium salts 2 react easily with ortho hydroxybenzonitriles 1 and 2-hydroxy-1-naphthonitriles 6 to give 1,3-benzoxazine and naphth[1,2- e ][1,3]oxazine derivatives respectively with a very good yield.

A NEW ONE‐FLASK PREPARATION OF 2‐(ALKYLAMINO)‐4‐CHLOROQUINAZOLINES FROM O‐AMINOBENZONITRILES AND PHOSGENIMINIUM SALTS

Aus den 2-Amino-benzonitrilen (I) entstehen mit den Phosgeniminium-Salzen (II) uber die isolierbaren Zwischenstufen (III) direkt die 2-Alkylamino-4-chlor-chinazoline (IV).