George Azevedo Lemos

Influence of temporomandibular disorder presence and severity on oral health-related quality of life

BACKGROUND AND OBJECTIVES: Temporomandibular disorders are highly prevalent and may impair several oral function- related aspects. This study aimed at evaluating the impact of the presence and severity of temporomandibular disorder signs and symptoms on oral health-related quality of life. METHODS: Participated in the study 135 dentistry students of the Federal University of Paraiba. The presence of temporomandibular disorder was determined by means of an anamnesis questionnaire and a summarized clinical evaluation protocol. Oral health-related quality of life was determined by the summarized Oral Health Impact Profile version translated and validated for the Portuguese language. Statistical comparisons between Oral Health Impact Profile-14 means related to the presence of temporomandibular disorder signs and symptoms were achieved with Mann-Whitney and Kruskal-Wallis tests. RESULTS: Volunteers with temporomandibular disorder (p<0.001), needing treatment (p<0.001) and higher severity (p<0.001) had higher impact on oral health-related quality of life. Volunteers with clinical temporomandibular disorder signs had further quality of life impairment, being that individuals with simultaneous muscle and joint temporomandibular disorders (p=0.034) had higher Oral Health Impact Profile-14 scores. Most impaired domains were physical pain (p=0.045), functional limitation (p=0.007) and psychological discomfort (p=0.045). CONCLUSION: Temporomandibular disorder severity has negative impact on quality of life, especially in volunteers with simultaneous joint and muscle clinical signs.

Correlação entre sinais e sintomas da Disfunção Temporomandibular (DTM) e severidade da má oclusão

Introduction The role of occlusion as an etiologic factor of temporomandibular disorders (TMD) has been polemic and still controversial. Objective To evaluate the correlation between signs and symptoms of temporomandibular disorders and severity of malocclusion. Method A total of 135 undergraduate dental students from Federal University of Paraiba were evaluated. The presence of TMD was estimated by Fonsecas Anamnestic Index and objective questions about symptoms were addressed. Students were also submitted to a summarized protocol for clinical evaluation of TMD. The evaluation of occlusal factors was performed using the Treatment Priority Index (TPI) applied to plaster casts corresponding to upper and lower dental arches. The differences between the means of IPT related to signs and symptoms of TMD were determined by t tests and One-way ANOVA. Correlations between occlusal factors and TMD were determined by Pearson correlation. Result According to the TPI, the severity of the malocclusion did not influence the onset of TMD, muscle or joint clinical signs and need for treatment. Class II malocclusion, marked overbite and rotated teeth were statistically correlated with the need for treatment and clinical signs of TMD. Conclusion In multifactor models as in the pathophysiology of TMD, occlusion can play a role as a co-factor in predisposing or perpetuating the different forms of TMD. As such, it should not be considered a major factor.

Effects of high molecular weight hyaluronic acid on induced arthritis of the temporomandibular joint in rats

High molecular weight hyaluronic acid (HMWHA) has been used to treat temporomandibular joint (TMJ) disorders, but controversial results have been described. This study aimed to characterize the morphological and biochemical actions of HMWHA on induced arthritis of the TMJ. Twenty-four male Wistar rats were used, and arthritis of the TMJ was induced through an intra-articular injection of Complete Freunds Adjuvant (CFA) (50 μl). One week after arthritis induction, the animals were treated with HMWHA (once per week for three weeks). Histological analyses were performed using sections stained with hematoxylin-eosin, toluidine blue and Picrosirius. Were also performed histomorphometric analysis and birefringence of collagenous fibers (polarization microscopy). Biochemical analyses of TMJ tissues were carried out through measurements of sulfated glycosaminoglycans and zymography for evaluation of metalloproteinase-2 and -9 (MMP-2 and -9). Data were analyzed using paired t-test and unpaired t-test, with a 5% significance level. HMWHA reduced histologic changes and thickness of the articular disc, led to a greater arrangement of collagenous fibers, lower concentration of sulfated glycosaminoglycans and lower activity in all isoforms of MMP-2 and -9 in TMJs with induced arthritis. These findings suggest that HMWHA may exert a protective effect on the TMJ.

Prevalência de sinais e sintomas de disfunção temporomandibular em estudantes pré-vestibulandos: associação de fatores emocionais, hábitos parafuncionais e impacto na qualidade de vida

The aim of this study was to evaluate the prevalence of temporomandibular disorders (TMD) signs and symptoms, its correlation with gender, parafunctional habits, emotional stress, anxiety, and depression and its impact on oral health-related quality of life (OHRQL) in college preparatory students at public and private institutions in João Pessoa, Paraíba (PB). The sample consisted of 303 students. Presence of TMD symptoms was determined by an anamnesis questionnaire containing questions related to the presence of parafunctional habits and emotional stress. A simplified clinical evaluation protocol was used. Anxiety and depression were determined with the Hospital Anxiety and Depression (HAD) scale and the OHRQL using the short version contained in the Oral Health Impact Profile (OHIP-14). The Chi-square, Fisher Exact, Mann Whitney, and Kruskal-Wallis tests were performed. Presence of signs and symptoms of TMD was statistically associated (p ≤ 0,05) with female gender, parafunctional habits, emotional stress, and anxiety, and represented greater impairment of the OHRQL. The physical pain domain was the most affected. The increased prevalence of signs and symptoms of TMD among college preparatory students indicates that there is a need for education and clarification among teachers and students to improve early diagnosis and to prevent the problem.

Retrospective review of patients referred to a temporomandibular dysfunction care setting of a Brazilian public university

Background and oBjectives: The objective of this study is to describe the restrospective analysis of medical records of patients with temporomandibular disorder in a healthcare service of a Brazilian public university. The prevalence of signs and symptoms of temporomandibular disorder, associated factors, diagnosis and observations related to the treatment were recorded. MetHods: Two hundred and thirteen medical records were assessed by one single surveyor from March 2013 to December 2014. Information about sociodemographic factors, prevalence of symptoms of temporomandibular disorder and treatment need were collected (Fonseca Anamnestic Index), clinical examination, diagnosis, treatments and referral to other professionals. resuLts: The majority of patients were female (81.7%), single (53.0%), students (23.3%) between 20 and 29 years of age (26.8%). Pain was reported by 50.4% of patients. According to FAI, 41.8% of patients were classified with severe synptoms of temporomandibular disorder and 73.2% identified with the need of treatment. Presence of temporomandibular disorder symptoms (p = 0.001) and need of treatment (p <0.001) were significantly associated to the female gender. The most prevalent diagnosis was muscle temporomandibular disorder (41.5%) and the most affected muscle was the masseter (21.3%). The most common treatments were occlusal splint (27.6%) and counseling (22.6%). concLusion: The greater demand for temporomandibular disorder treatment came from young patients, single, female, complaining from pain. The prevalence of temporomandibular disorder symptoms was high, muscular disorders was the most Retrospective review of patients referred to a temporomandibular dysfunction care setting of a Brazilian public university Revisão retrospectiva de pacientes encaminhados a um serviço de disfunção temporomandibular de uma universidade pública brasileira Wellington Pereira de Moura1, Pâmela Lopes Pedro da Silva2, George Azevedo Lemos3, Paulo Rogério Ferreti Bonan4, Robinsom Viégas Montenegro2, André Ulisses Dantas Batista2 1. Universidade Federal da Paraíba, João Pessoa, PB, Brasil. 2. Universidade Federal da Paraíba, Departamento de Restauração Dental, João Pessoa, PB, Brasil. 3. Universidade Estadual de Campinas, Campinas, SP, Brasil. 4. Universidade Federal da Paraíba, Departamento Clínico e Odontologia Social, João Pessoa, PB, Brasil. Submitted in October 24, 2016. Accepted for publication in May 15, 2017. Conflict of interests: none – Sponsoring sources: none. correspondence to: Cidade Universitária, s/n Castelo Branco 58051-900 João Pessoa, PB, Brasil. E-mail: lemos.george@yahoo.com.br

Experimental model of temporomandibular joint arthritis: Evaluation of contralateral joint and masticatory muscles

OBJECTIVE To investigate morphological and biochemical changes in an experimental model of temporomandibular joint (TMJ) arthritis, as well as examine contralateral joint involvement and morphometric aspects of masticatory muscles in affected animals. DESIGN Forty Wistar rats were allocated into three groups, as follows: a healthy control group (HG); and a group with arthritis induced in the left TMJ (IG); and a contralateral group with noninflamed right TMJ (CG). Arthritis was induced by intra-articular injection of 50 μL of Complete Freunds Adjuvant (CFA). Morphological analysis was performed using histological sections of TMJs stained with hematoxylin-eosin, picrosirius and toluidine blue. In addition, histomorphometric analyses of the articular cartilage, articular disc and masticatory muscles, were performed. Biochemical analysis of TMJ tissues included dosage of sulfated glycosaminoglycans (GAGs), zymography of the Matrix Metalloproteinases (MMPs) 2 and 9 and ELISA for the cytokines IL-6, TNF-α and IL-1β. The data were analyzed by paired and unpaired t-tests, with a p < 0.05. RESULTS IG animals presented morphological and biochemical changes in their TMJ, including synovial membrane hyperplasia; chronic inflammatory infiltrate; collagen fiber disorganization in the disc; reduced proteoglycans in the cartilage; greater disc thickness; lower cartilage thickness; lower feed intake; higher activity of MMP-9 and MMP-2, and higher concentration of IL-6, TNF-α, and IL-1β, as compared to HG. CG animals showed posterior disc thickening; reduced proteoglycans in the cartilage; lower collagen fiber organization of the disc; active MMP-9, and higher concentration of IL-6 and TNF-α compared to HG animals. Articular inflammation reduced the area and diameter of fibers of the temporal (right), medial pterygoid (left), and lateral pterygoid (right and left) muscles as compared to HG animals. CONCLUSION TMJ arthritis reduced the area and diameter of masticatory muscle fibers and caused morphological and molecular changes in the contralateral joint.

Atenção em saúde bucal: avaliação dos centros de especialidades odontológicas da Paraíba

Este estudo objetivou avaliar a Politica Nacional de Saude Bucal na atencao de media complexidade, considerando o desempenho dos Centros de Especialidades Odontologicas (CEOs) da Paraiba. Foram avaliados 19 CEOs, utilizando-se dados secundarios da producao de 2007 a 2010, registrados pelo Sistema de Informacao Ambulatorial do Sistema Unico de Saude (SIA/SUS). Os dados foram obtidos, tabulados e organizados de acordo com os subgrupos de procedimentos odontologicos, segundo a Portaria Ministerio da Saude/Gabinete do Ministro n° 600. O desempenho insatisfatorio dos CEOs e revelador de falhas, especialmente na gestao e na organizacao desses servicos. O processo de avaliacao e uma etapa fundamental para garantir uma melhor qualidade dos servicos a populacao.