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Hitoshi Shimizu

Chugai Pharmaceutical Co.

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Publication

Featured researches published by Hitoshi Shimizu.

Organic Process Research & Development | 2005

Industrial Synthesis of Maxacalcitol, the Antihyperparathyroidism and Antipsoriatic Vitamin D3 Analogue Exhibiting Low Calcemic Activity

Hitoshi Shimizu; Kazuki Shimizu; Noboru Kubodera; Tetsuhiro Mikami; Kaname Tsuzaki; Hiroyuki Suwa; Koji Harada; Akira Hiraide; Motoki Shimizu; Kaichiro Koyama; Yoshihide Ichikawa; Daisuke Hirasawa; Yasushi Kito; Mio Kobayashi; Masaharu Kigawa; Masahiro Kato; Toshiro Kozono; Hideki Tanaka; Makoto Tanabe; Masanori Iguchi; Mitsutaka Yoshida

Tetrahedron Letters | 2004

Efficient modification of steroid 20S-hydroxy functionality for industrial preparation of 1α,25-dihydroxy-22-oxavitamin D3, Maxacalcitol

Hitoshi Shimizu; Kazuki Shimizu; Noboru Kubodera; Kenichi Yakushijin; David A. Horne

Heterocycles | 2004

Regioselective Cleavage of Trisubstituted Epoxy-Linkage Using Lithium Trialkylborohydride Reagents: A New Route to the Key Intermediate of Maxacalcitol

Hitoshi Shimizu; Kazuki Shimizu; Noboru Kubodera; Kenichi Yakushijin; David Horne

Archive | 2001

Process for producing erythromycin derivative

Hitoshi Shimizu; Kaname Tsuzaki; Mitsuhiro Kurita

Archive | 2001

Erythromycin derivative having novel crystal structures and processes for their production

Akira Hiraide; Kaichiro Koyama; Hitoshi Shimizu; Kaname Tsuzaki

Journal of Synthetic Organic Chemistry Japan | 2009

Practical Synthesis of Maxacalcitol Based on Usefully Classical Reactions and Photolysis

Hitoshi Shimizu; Tetsuhiro Mikami; Masahiro Kato

Tetrahedron Letters | 2004

Synthesis of 21-nor-22-oxa-1α,25-dihydroxyvitamin D3 derivatives in quest of a drug with low calcemic activity

Hitoshi Shimizu; Kazuki Shimizu; Yasushi Uchiyama; Atsuko Sugita; Tetsuhiro Mikami; Tsuyoshi Yamauchi; Masahiro Kato; Kazumi Morikawa

Organic Process Research & Development | 2018

Development of a Kilogram-Scale Synthesis of a Novel Anti-HCV Agent, CH4930808

Tsuyoshi Haneishi; Yoshiaki Kato; Hiroshi Fukuda; Tomoyuki Shimamura; Takemi Tanokura; Akira Hiraide; Kaichiro Koyama; Masato Fudesaka; Kenji Maeda; Nobuyuki Nakata; Masahiro Nagase; Takahiko Yabuzaki; Hiroaki Takao; Masaharu Kigawa; Hitoshi Shimizu; Makoto Shimizu

Heterocycles | 2006

Total inversion of cis-C5 maxacalcitol into its trans-C5 isomer via the sulforene intermediate

Tsuyoshi Yamauchi; Koji Suzuki; Hitoshi Shimizu; Masahiro Kato

Archive | 2003

Anhydrate/hydrate of an erythromycin derivative and processes for preparing said anhydrate/hydrate

Kenji Kamada; Akira Hiraide; Kaichiro Koyama; Hitoshi Shimizu; Gary H. Ward; Vandana K. Cheruvallath; Stephan Parent

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Kazuki Shimizu

Chugai Pharmaceutical Co.

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Masahiro Kato

Chugai Pharmaceutical Co.

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Kenji Maeda

Chugai Pharmaceutical Co.

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Masahiro Nagase

Chugai Pharmaceutical Co.

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Noboru Kubodera

Chugai Pharmaceutical Co.

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Tetsuhiro Mikami

Chugai Pharmaceutical Co.

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Hiroshi Fukuda

National Institute of Radiological Sciences

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Makoto Shimizu

Mie University

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Tsuyoshi Haneishi

Mie University

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Tsuyoshi Yamauchi

Chugai Pharmaceutical Co.

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