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Dive into the research topics where Jaan A. Pesti is active.

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Featured researches published by Jaan A. Pesti.


Synthetic Communications | 1999

A PRACTICAL PREPARATION OF THIOL CARBOXYLIC ESTERS OF 2-(ISOXAZOLYL) ACETIC ACIDS

Jaan A. Pesti; Jianguo Yin; Jihchin Chung

Abstract High yields of several thiolesters of 2-[3-(4-cyanophenyl)-4,5-dihydro-5-isoxazolyl]acetic acid are easily prepared from the corresponding oxoester by the reaction with trimethyl silylated mercaptan and aluminum chloride. The selection of mercaptans expands the previous scope of this synthetic method.


Organic Letters | 2000

An Efficient Chiral Moderator Prepared from Inexpensive (+)-3-Carene: Synthesis of the HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitor DPC 963

Goss S. Kauffman; Gregory D. Harris; Roberta L. Dorow; Benjamin R. P. Stone; Rodney L. Parsons; Jaan A. Pesti; Nicholas A. Magnus; Joseph M. Fortunak; Pat N. Confalone; William A. Nugent


Journal of Organic Chemistry | 1997

Rearrangement of Nα-Protected l-Asparagines with Iodosobenzene Diacetate. A Practical Route to β-Amino-l-alanine Derivatives

Lin-hua Zhang; Goss S. Kauffman; Jaan A. Pesti; Jianguo Yin


Organic Process Research & Development | 2016

Tetramethyldisiloxane: A Practical Organosilane Reducing Agent

Jaan A. Pesti; Gerald L. Larson


Organic Process Research & Development | 2009

The Process Development of Ravuconazole: An Efficient Multikilogram Scale Preparation of an Antifungal Agent(1)

Jaan A. Pesti; Chien-Kuang Chen; Lori Spangler; Albert J. DelMonte; Serge Benoit; Derek Berglund; Jeffrey T. Bien; Paul R. Brodfuehrer; Yeung Y. Chan; Elisabeth Corbett; Carrie A. Costello; Paul Demena; Robert P. Discordia; Wendel W. Doubleday; Zhinong Gao; Stephane Gingras; John Anthony Grosso; Oscar W. Haas; David Kacsur; Chiajen Lai; Simon Leung; Melanie Miller; Jale Muslehiddinoglu; Nina Nguyen; Jun Qiu; Martina Olzog; Emily A. Reiff; Dominique Thoraval; Michael J. Totleben; Dale Vanyo


Journal of Organic Chemistry | 1999

An Alternative Approach for the Conversion of Aldehydes to Terminal Alkynes.

Zhe Wang; Jianguo Yin; Silvio Campagna; Jaan A. Pesti; Joseph M. Fortunak


Journal of the American Chemical Society | 2001

Reversible Michael Reaction−Enzymatic Hydrolysis: A New Variant of Dynamic Resolution

Jaan A. Pesti; Jianguo Yin; Lin-hua Zhang; Luigi Anzalone


Organic Process Research & Development | 2004

Efficient Preparation of a Key Intermediate in the Synthesis of Roxifiban by Enzymatic Dynamic Kinetic Resolution on Large Scale

Jaan A. Pesti; Jinguao Yin; Lin-hua Zhang; Luigi Anzalone; Robert E. Waltermire; Philip Ma; Edward Gorko; Pat N. Confalone; Joseph M. Fortunak; Charlotte Silverman; John A. Blackwell; J. C. Chung; Michael Hrytsak; Mary Cooke; Lakisha Powell; Charles E. Ray


Journal of Organic Chemistry | 2000

Efficient Pyridinylmethyl Functionalization: Synthesis of 10,10-Bis[(2-fluoro-4-pyridinyl)methyl]-9(10H)-anthracenone (DMP 543), an Acetylcholine Release Enhancing Agent†

Jaan A. Pesti; George F. Huhn; Jianguo Yin; and Yide Xing; Joseph M. Fortunak; Richard A. Earl


Organic Process Research & Development | 2015

Development of a Two-Step, Enantioselective Synthesis of an Amino Alcohol Drug Candidate

Michael A. Schmidt; Emily A. Reiff; Xinhua Qian; Chao Hang; Vu Chi Truc; Kenneth J. Natalie; Chenchi Wang; Jacob Albrecht; Andrew Lee; Ehrlic Lo; Zhiwei Guo; Animesh Goswami; Steven L. Goldberg; Jaan A. Pesti; Lucius T. Rossano

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