Jacques Grégoire

Emotional plasticity : conditions and effects of improving emotional competence in adulthood

This study aimed to investigate (a) whether it is possible to increase emotional competence (EC) in adulthood; (b) whether this improvement results in better mental, physical, and social adjustment; (c) whether this improvement can be maintained 1 year later; and (d) whether these benefits are accompanied by a reduction in stress-hormone secretion (i.e., cortisol). One hundred and thirty-two participants were randomly assigned to an EC-enhancing intervention (in group format) or to a control group. Participants in the intervention group underwent a specifically designed 15-hr intervention targeting the 5 core emotional competencies, complemented with a 4-week e-mail follow-up. Results reveal that the level of emotional competencies increased significantly in the intervention group in contrast with the control group. This increase resulted in lower cortisol secretion, enhanced subjective and physical well-being, as well as improved quality of social and marital relationships in the intervention group. No significant change occurred in the control group. Peer reports on EC and quality of relationships confirmed these results. These data suggest that emotional competencies can be improved, with effective benefits on personal and interpersonal functioning lasting for at least 1 year. The theoretical implications of these results as well as their practical implications for the construction and the development of effective emotional competencies interventions are discussed.

Effect of age on forward and backward digit spans

Abstract A number of studies has suggested that aging is characterized by a decline in the central executive while the automatic processes (in particular operations by the phonological loop) remain intact. According to interpretation, age differences should be minimal in verbal forward digit span while they should be more important in backward verbal digit span. A sample of 1,000 subjects with ages ranging from 16 years to 79 years was used to test this hypothesis. the results show no significant effect of age on the difference between digit span forward and backward. the theoretical implications of these results are discussed.

Rational numbers: Componential versus holistic representation of fractions in a magnitude comparison task

This study investigated whether the mental representation of the fraction magnitude was componential and/or holistic in a numerical comparison task performed by adults. In Experiment 1, the comparison of fractions with common numerators (x/a_x/b) and of fractions with common denominators (a/x_b/x) primed the comparison of natural numbers. In Experiment 2, fillers (i.e., fractions without common components) were added to reduce the regularity of the stimuli. In both experiments, distance effects indicated that participants compared the numerators for a/x_b/x fractions, but that the magnitudes of the whole fractions were accessed and compared for x/a_x/b fractions. The priming effect of x/a_x/b fractions on natural numbers suggested that the interference of the denominator magnitude was controlled during the comparison of these fractions. These results suggested a hybrid representation of their magnitude (i.e., componential and holistic). In conclusion, the magnitude of the whole fraction can be accessed, probably by estimating the ratio between the magnitude of the denominator and the magnitude of the numerator. However, adults might prefer to rely on the magnitudes of the components and compare the magnitudes of the whole fractions only when the use of a componential strategy is made difficult.

Compliance in depressed patients treated with fluoxetine or amitriptyline

Two dimensions of compliance (drop-outs and adherence) were investigated in patients treated with antidepressant drugs. Efficacy, compliance and its determinants were investigated in 66 patients suffering from major depressive disorder and treated in a double-blind manner with fluoxetine 20 mg/day or amitriptyline 150 mg/day for 9 weeks. Overall effectiveness [50% decrease in the initial Hamilton Rating Scale for Depression (HAM-D)] was similar in both groups (62.8% for fluoxetine, 58.1% for amitriptyline). The dropout rate due to side effects was 35.5% for amitriptyline and 5.7% for fluoxetine. A logistic regression analysis revealed that the initial HAM-D score was not predictive for dropping out, but this outcome was instead determined by sex (increased risk for males), age (increased risk for being younger) and occurrence of severe side effects. Adherence was estimated using electronic Medication Event Monitoring System and defined as the percentage of days when the correct dose was taken out of the medication container. Of the patients studied 37% had an adherence of less than 70%. There was no relationship between adherence and efficacy and adherence was similar in patients on fluoxetine or amitriptyline. Side effects were not predictive of being adherent or not, but a higher initial HAM-D score predicted a higher adherence to the medication regimen. The demographic variables bad no significant effect. The present study suggests that the link between efficacy, side effects and compliance or adherence is more complex than is generally believed and that early termination and non-adherence seem to be determined by different factors.

The Profile of Emotional Competence (PEC): development and validation of a self-reported measure that fits dimensions of emotional competence theory

Emotional Competence (EC), which refers to individual differences in the identification, understanding, expression, regulation and use of one’s own emotions and those of others, has been found to be an important predictor of individuals’ adaptation to their environment. Higher EC is associated with greater happiness, better mental and physical health, more satisfying social and marital relationships and greater occupational success. While it is well-known that EC (as a whole) predicts a number of important outcomes, it is unclear so far which specific competency(ies) participate(s) in a given outcome. This is because no measure of EC distinctly measures each of the five core emotional competences, separately for one’s own and others’ emotions. This lack of information is problematic both theoretically (we do not understand the processes at stake) and practically (we cannot develop customized interventions). This paper aims to address this issue. We developed and validated in four steps a complete (albeit short: 50 items) self-reported measure of EC: the Profile of Emotional Competence. Analyses performed on a representative sample of 5676 subjects revealed promising psychometric properties. The internal consistency of scales and subscales alike was satisfying, factorial structure was as expected, and concurrent/discriminant validity was good.

Adherence to treatment regimen in depressed patients treated with amitriptyline or fluoxetine

OBJECTIVE Non-compliance presents a constant challenge to effective therapy. Many studies only investigate early treatment discontinuation and not other measures like adherence to treatment regimen. We compared adherence in depressed patients using either a selective serotonin reuptake inhibitor (fluoxetine) or a tricyclic antidepressant (amitriptyline), and examined its clinical relevance through adverse events, drop-out rates, and outcome. Adherence was measured electronically with the MEMS (Medication Event Monitoring System). DESIGN Nine-week double blind, randomized controlled trial. SETTING Ambulatory psychiatric care. PATIENTS Random sample of 66 depressed (DSM-III-R criteria) patients. INTERVENTION Fluoxetine 20 mg or amitriptyline 150 mg. MAIN OUTCOME MEASURES Time course of adherence and its relation to severe adverse events, drop-outs and outcome. RESULTS Non-adherence to the treatment regimen occurred frequently in both treatment groups: 31% of patients had at least one 3-day drug holiday, and 34% of patients had at least one episode of three pills in a 24-h period. Over-consumption occurred more frequently during the early phases of treatment while under-consumption occurred more frequently during the later phases. Patients on amitriptyline (P=0.03) and patients with a higher pill intake (P=0.01) experienced more severe adverse events. Patients on amitriptyline (P=0.009) and patients with a lower adherence to the treatment regimen (P=0.004) discontinued from treatment more frequently. The final Hamilton score was significantly predicted by a longer duration of treatment and by a better adherence, but only in amitriptyline users. CONCLUSIONS Non-adherence to the treatment regimen has important clinical consequences. Pharmacodynamics and human behavior predict risk for severe adverse events and drop-outs. Moreover, in amitriptyline users but not in fluoxetine users, better adherence predicts a better outcome.

Numerical and nonnumerical estimation in children with and without mathematical learning disabilities

There are currently multiple explanations for mathematical learning disabilities (MLD). The present study focused on those assuming that MLD are due to a basic numerical deficit affecting the ability to represent and to manipulate number magnitude (Butterworth, 1999, 2005; A. J. Wilson & Dehaene, 2007) and/or to access that number magnitude representation from numerical symbols (Rousselle & Noël, 2007). The present study provides an original contribution to this issue by testing MLD children (carefully selected on the basis of preserved abilities in other domains) on numerical estimation tasks with contrasting symbolic (Arabic numerals) and nonsymbolic (collection of dots) numbers used as input or output. MLD children performed consistently less accurately than control children on all the estimation tasks. However, MLD children were even weaker when the task involved the mapping between symbolic and nonsymbolic numbers than when the task required a mapping between two nonsymbolic numerical formats. Moreover, in the estimation of nonsymbolic numerosities, MLD children relied more than control children on perceptual cues such as the cumulative area of the dots. Finally, the task requiring a mapping from a nonsymbolic format to a symbolic format was the best predictor of MLD. In order to explain these present results, as well as those reported in the literature, we propose that the impoverished number magnitude representation of MLD children may arise from an initial mapping deficit between number symbols and that magnitude representation.

Validation of the Quality of Life in Depression Scale in a population of adult depressive patients aged 60 and above.

The aim of this study is to evaluate the validity of the Dutch version of the Quality of Life in Depression Scale (QLDS) in a population of depressive patients aged 60 years and over, who were seen on an outpatient basis by psychiatrists in the Flemish region of Belgium. A sample of severely depressive patient was followed during an height-week medical treatment. During this period, each patient was evaluated four times with the Hamilton Rating Scale for Depression and with the QLDS. We observed that the QLDS was very sensitive to the failing of the quality of life in depressive states. The QLDS was also a very good measure of change during the improvement of depressives states. Furthermore, the scale appears to be very homogeneous across the depressive states range. The results are very encouraging, and constitute strong corroboration of the construct validity of the scale.

Development and Construct Validation of an Academic Emotions Scale.

This article describes the development and two studies on the construct validity of the Academic Emotions Scale (AES). The AES is a French self-report questionnaire assessing six emotions in the context of school learning: enjoyment, hope, pride, anxiety, shame and frustration. Its construct validity was studied through exploratory and confirmatory factor analyses. A six-factor structure emerged from exploratory factor analyses on two different samples (N = 188; N = 516). These six factors correspond to six academic emotions. Confirmatory factor analysis was conducted to test the factorial structure of the final version of the AES. A hierarchical model with a second-order factor (valence) underlying the six first-order emotional factors was the most suited to the data. The psychometric characteristics of the AES justify the use of this questionnaire in future research.

Factor Structure of the French Version of the Wechsler Adult Intelligence Scale–III

The standardization of the French version of the Wechsler Adult Intelligence Scale (WAIS-III) was conducted after carefully adapting the French version fromthe U.S. version and extensive field testing. The standardization sample was composed of 1,104 participants from 16 to 89 years. To assess the construct validity of the French version, exploratory and confirmatory factor analyses were performed. Two-factor, three-factor, and four-factor models were compared. The four-factor solution fitted the data much better than did the two-and three-factor solutions. The only problem observed was with the Arithmetic subtest, which did not show clear alignment with the Working Memory factor. Otherwise, the factor structure of the U.S. WAIS-IIIwas replicated with its French adaptation. Despite important changes in five verbal subtests, very similar factor structure was observed between the U.S. and the French standardization samples. This is an important indication of the universality of the factor structure underlying the WAIS-III.