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Featured researches published by Jakub Gregor.


Journal of Medical Internet Research | 2013

Interactive algorithms for teaching and learning acute medicine in the network of medical faculties MEFANET

Daniel Schwarz; Petr Štourač; Martin Komenda; Hana Harazim; Martina Kosinová; Jakub Gregor; Richard Hůlek; Olga Smékalová; Ivo Křikava; Roman Štoudek; Ladislav Dušek

Background Medical Faculties Network (MEFANET) has established itself as the authority for setting standards for medical educators in the Czech Republic and Slovakia, 2 independent countries with similar languages that once comprised a federation and that still retain the same curricular structure for medical education. One of the basic goals of the network is to advance medical teaching and learning with the use of modern information and communication technologies. Objective We present the education portal AKUTNE.CZ as an important part of the MEFANET’s content. Our focus is primarily on simulation-based tools for teaching and learning acute medicine issues. Methods Three fundamental elements of the MEFANET e-publishing system are described: (1) medical disciplines linker, (2) authentication/authorization framework, and (3) multidimensional quality assessment. A new set of tools for technology-enhanced learning have been introduced recently: Sandbox (works in progress), WikiLectures (collaborative content authoring), Moodle-MEFANET (central learning management system), and Serious Games (virtual casuistics and interactive algorithms). The latest development in MEFANET is designed for indexing metadata about simulation-based learning objects, also known as electronic virtual patients or virtual clinical cases. The simulations assume the form of interactive algorithms for teaching and learning acute medicine. An anonymous questionnaire of 10 items was used to explore students’ attitudes and interests in using the interactive algorithms as part of their medical or health care studies. Data collection was conducted over 10 days in February 2013. Results In total, 25 interactive algorithms in the Czech and English languages have been developed and published on the AKUTNE.CZ education portal to allow the users to test and improve their knowledge and skills in the field of acute medicine. In the feedback survey, 62 participants completed the online questionnaire (13.5%) from the total 460 addressed. Positive attitudes toward the interactive algorithms outnumbered negative trends. Conclusions The peer-reviewed algorithms were used for conducting problem-based learning sessions in general medicine (first aid, anesthesiology and pain management, emergency medicine) and in nursing (emergency medicine for midwives, obstetric analgesia, and anesthesia for midwifes). The feedback from the survey suggests that the students found the interactive algorithms as effective learning tools, facilitating enhanced knowledge in the field of acute medicine. The interactive algorithms, as a software platform, are open to academic use worldwide. The existing algorithms, in the form of simulation-based learning objects, can be incorporated into any educational website (subject to the approval of the authors).


international symposium on environmental software systems | 2013

GENASIS System Architecture

Richard Hůlek; Jiří Jarkovský; Miroslav Kubásek; Jakub Gregor; Jiří Hřebíček; Ladislav Dušek; Jana Klánová; Kateřina Šebková; Jana Borůvková; Ivan Holoubek

GENASIS (Global ENvironmental ASsessment and Information System) is the web environmental information system which is an environmental data repository that provides comprehensive information on chemical contamination of the environment by Persistent Organic Pollutants (POPs). GENASIS combines data from long-term environmental monitoring programmes operated by RECETOX with validated data from partner institutions, and provides data archives, data management services and analytical processing of data. In the past few years the GENASIS system has undergone rapid development and grew up from the data repository into a scientific data infrastructure.


international symposium on environmental software systems | 2017

GMP Data Warehouse – a Supporting Tool of Effectiveness Evaluation of the Stockholm Convention on Persistent Organic Pollutants

Jakub Gregor; Jana Borůvková; Richard Hůlek; Jiří Kalina; Kateřina Šebková; Jiří Jarkovský; Ladislav Dušek; Jana Klánová

The Stockholm Convention on Persistent Organic Pollutants is multilateral environmental agreement focused on selected persistent organic pollutants (POPs) for which the contracting Parties must adopt measures to eliminate or reduce their production and use or minimise the unintentional releases. One of the tools for the effectiveness evaluation of the Stockholm Convention is Global Monitoring Plan for Persistent Organic Pollutants (GMP) – a project that aims to collect global data on POPs concentrations in selected environmental matrices. This paper introduces an information system GMP Data Warehouse, which was developed in order to provide user-friendly tools for the collection, storage, analyses and visualisation of data from international POPs monitoring activities.


international symposium on environmental software systems | 2013

Estimating Impacts of Environmental Interventions in Monitoring Programs Requires Conceptual Data Models and Robust Statistical Processing

Ladislav Dušek; Jana Klánová; Jiří Jarkovský; Jakub Gregor; Richard Hůlek; Ivan Holoubek; Jiří Hřebíček

This paper discusses main problems associated with evaluation of performance and impact of long-term environmental programs. Lack of data standards, incompleteness of archived datasets and insufficient statistical power were identified as main limits in functionality of monitoring networks. To avoid these failures, environmental programs should be designed with inception to incorporate data management as their integral part. Especially in global programs, local and regional data managers should invest significant proportion of their effort to handle documentation in terms of standardized coding, data formats, metadata coding and consistency of records over time. Up-to-date trends in building knowledge-based infrastructures are illustrated using example of monitoring of atmospheric pollution by persistent organic pollutants (POPs). Conceptual model usable to facilitate the integration and analysis of data on POPs concentrations is introduced with its multilayer hierarchy of entities (POPs as nomenclature classes, couples “observation – measurement” as content classes). Robust set of statistical methods for processing of time series of concentration data is discussed from the viewpoint of practical implementation within running monitoring programs. It consists of the following components: baseline pollution estimates, uncertainty analyses, spatial extrapolations, effect size estimates, time trend identification and quantification. Development of tools supporting standardized environmental data management is rapidly expanding field of science which results in the following challenges for applied informatics and statistics: log-term sustainability of information systems, data-related metadata coding and archiving, tools for automated integration and reporting of data.


international symposium on environmental software systems | 2013

GENASIS: On-Line Data Browser for Environmental Monitoring and Associated Information Systems

Jiří Jarkovský; Ladislav Dušek; Miroslav Kubásek; Richard Hůlek; Jakub Gregor; Jiří Hřebíček; Jana Klánová; Kateřina Šebková; Jana Borůvková; Ivan Holoubek

The current environmental research is producing large quantities of data on all environmental matrices and number of chemical and biological endpoints. However, there is a paradox in this situation that we suffer from lack of representative data, since their production has not been accordingly supported by development of systems that make them accessible for analysis. The introduced GENASIS data browser aims in its current version on the problem of persistent organic pollutants and the analysis, visualization and interpretation of data from their monitoring networks. The development of the GENASIS involves problems of the so called information pyramid: monitoring (obtaining environmental data), data validation (including uncertainty quantification), data analysis, and methods of aggregation of data from different sources, model generalization and interpretation of results, and their presentation. Within the frame of the GENASIS data browser, we introduce a user-friendly system for the visualization and analysis of contamination of all environmental compartments by persistent organic pollutants and evaluation of actual POPs contamination, its long-term trends and seasonal fluctuations. Project outcomes are useful as information source both for lay public and experts, as well as for the process of the Stockholm Convention implementation.


international symposium on environmental software systems | 2013

Tools for Collection, Analysis and Visualization of Data from the Stockholm Convention Global Monitoring Plan on Persistent Organic Pollutants

Jakub Gregor; Richard Hůlek; Jiří Jarkovský; Jana Borůvková; Jiří Kalina; Kateřina Šebková; Daniel Schwarz; Jana Klánová; Ladislav Dušek

The Global Monitoring Plan for persistent organic pollutants is an important component of the effectiveness evaluation of the Stockholm Convention and its main objective is assessment of long-term changes in POPs concentrations in core matrices – ambient air and human tissues (milk, blood). This paper summarizes results of activities of the Research Centre for Toxic Compounds in the Environment and the Institute of Biostatistics and Analyses, Masaryk University, Czech Republic, which have been performed on the basis of the mandate given by Global Coordination Group for GMP and Secretariat of the Stockholm Convention: content analysis of the GMP monitoring reports published in 2009, on-line visualization tool for browsing and analyzing collected data from the monitoring reports, and proposal of a design of future data collection campaigns.


Water Research | 2004

Freshwater phytoplankton quantification by chlorophyll a: a comparative study of in vitro, in vivo and in situ methods.

Jakub Gregor; Blahoslav Maršálek


Water Research | 2007

Detection and estimation of potentially toxic cyanobacteria in raw water at the drinking water treatment plant by in vivo fluorescence method

Jakub Gregor; Blahoslav Maršálek; Helena Šípková


Acta Hydrochimica Et Hydrobiologica | 2005

A Simple In Vivo Fluorescence Method for the Selective Detection and Quantification of Freshwater Cyanobacteria and Eukaryotic Algae

Jakub Gregor; Blahoslav Maršálek


Environmental Toxicology | 2007

Effects of aqueous extracts from five species of the family Papaveraceae on selected aquatic organisms

Daniel Jančula; Jana Suchomelová; Jakub Gregor; Marie Smutná; Blahoslav Maršálek; Eva Táborská

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Miroslav Zavoral

Charles University in Prague

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