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James H. Prescott

Preston

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Publication

Featured researches published by James H. Prescott.

Nature Biotechnology | 2006

Chronic, programmed polypeptide delivery from an implanted, multireservoir microchip device

James H. Prescott; Sara A. Lipka; Samuel P. Baldwin; Norman F. Sheppard; John M. Maloney; Jonathan R. Coppeta; Barry Yomtov; Mark A. Staples; John T. Santini

Implanted drug delivery systems are being increasingly used to realize the therapeutic potential of peptides and proteins. Here we describe the controlled pulsatile release of the polypeptide leuprolide from microchip implants over 6 months in dogs. Each microchip contains an array of discrete reservoirs from which dose delivery can be controlled by telemetry.

Archive | 2007

Multi-reservoir pump device for dialysis, biosensing, or delivery of substances

John T. Santini; Michael F. Cima; Jonathan R. Coppeta; James H. Prescott; Zouhair Sbiaa; Mark A. Staples

Archive | 2004

Solid drug formulation and device for storage and controlled delivery thereof

James H. Prescott; Scott A. Uhland; Mark A. Staples; John T. Santini

Archive | 2003

Method and device for the controlled delivery of parathyroid hormone

Dennis Ausiello; John T. Santini; Stephen J. Herman; James H. Prescott

Archive | 2005

Devices and methods for measuring and enhancing drug or analyte transport to/from medical implant

Stephen J. Herman; Timothy Kreiger; John T. Santini; James H. Prescott; Mark A. Staples; Sara A. Lipka

Archive | 2006

Passive wear-indicating sensor for implantable prosthetic device

Michael J. Cima; Jr. John T. Santini; Kurt Shelton; James H. Prescott; Mark A. Staples; Jonathan R. Coppeta

Archive | 2006

Control of drug release by transient modification of local microenvironments

James H. Prescott; Timothy Kreiger; Elizabeth Rees Proos

Pharmaceutical Research | 2008

Long-term stability and in vitro release of hPTH(1-34) from a multi-reservoir array.

Elizabeth Rees Proos; James H. Prescott; Mark A. Staples

Pharmaceutical Research | 2007

Dosage form development, in vitro release kinetics, and in vitro-in vivo correlation for leuprolide released from an implantable multi-reservoir array.

James H. Prescott; Timothy Krieger; Sara A. Lipka; Mark A. Staples

Archive | 2009

Implantable device for controlled, extended delivery of parathyroid hormone

Dennis Ausiello; John T. Santini; Stephen J. Herman; James H. Prescott; Scott A. Uhland; John M. Maloney; Benjamin F. Polito

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John T. Santini

Massachusetts Institute of Technology

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Mark A. Staples

Preston

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Stephen J. Herman

Massachusetts Institute of Technology

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Sara A. Lipka

Preston

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Scott A. Uhland

Massachusetts Institute of Technology

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Timothy Kreiger

Preston

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Dennis Ausiello

Preston

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Jonathan R. Coppeta

Preston

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John M. Maloney

Preston

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Barry Yomtov

Preston

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