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Dive into the research topics where Jonathan R. Coppeta is active.

Publication


Featured researches published by Jonathan R. Coppeta.


Nature Biotechnology | 2006

Chronic, programmed polypeptide delivery from an implanted, multireservoir microchip device

James H. Prescott; Sara A. Lipka; Samuel P. Baldwin; Norman F. Sheppard; John M. Maloney; Jonathan R. Coppeta; Barry Yomtov; Mark A. Staples; John T. Santini

Implanted drug delivery systems are being increasingly used to realize the therapeutic potential of peptides and proteins. Here we describe the controlled pulsatile release of the polypeptide leuprolide from microchip implants over 6 months in dogs. Each microchip contains an array of discrete reservoirs from which dose delivery can be controlled by telemetry.


Archive | 2011

Low-permeability, laser-activated drug delivery device

Jonathan R. Coppeta; Kenneth N. Horne; John T. Santini; John A. Scholl; Gregory J.R. Spooner; Cynthia L. Stevenson; Naveed Shams; Andrew Poutiatine


Archive | 2003

Micro-reservoir osmotic release systems and microtube array device

Jonathan R. Coppeta; John T. Santini; Scott A. Uhland


Archive | 2007

Multi-reservoir pump device for dialysis, biosensing, or delivery of substances

John T. Santini; Michael F. Cima; Jonathan R. Coppeta; James H. Prescott; Zouhair Sbiaa; Mark A. Staples


Archive | 2005

Compression and cold weld sealing methods and devices

Jonathan R. Coppeta; Kurt Shelton; Norman F. Sheppard; Douglas B. Snell; Catherine M. B. Santini


Archive | 2006

Passive wear-indicating sensor for implantable prosthetic device

Michael J. Cima; Jr. John T. Santini; Kurt Shelton; James H. Prescott; Mark A. Staples; Jonathan R. Coppeta


Archive | 2005

Multi-cap reservoir devices for controlled release or exposure of reservoir contents

John T. Santini; Zouhair Sbiaa; Jonathan R. Coppeta; Scott A. Uhland; Norman F. Sheppard


Archive | 2006

Hermetically Sealed Devices for Controlled Release or Exposure of Reservoir Contents

Jonathan R. Coppeta; Scott A. Uhland; Benjamin F. Polito; Norman F. Sheppard; Christina M. Feakes; Douglas B. Snell; John T. Santini


Archive | 2005

Hermetically sealing using a cold welded tongue and groove structure

Jonathan R. Coppeta; Kurt Shelton; Norman F. Sheppard; Douglas B. Snell; Catherine M. B. Santini


Archive | 2011

Implantable Biosensor Device and Methods of Use Thereof

Jonathan R. Coppeta; Robert Farra; Kenneth L. Hilts; Norman F. Sheppard

Collaboration


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John T. Santini

Massachusetts Institute of Technology

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Norman F. Sheppard

Massachusetts Institute of Technology

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Scott A. Uhland

Massachusetts Institute of Technology

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Zouhair Sbiaa

Massachusetts Institute of Technology

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