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Dive into the research topics where Jeroen Knops is active.

Publication


Featured researches published by Jeroen Knops.


Nature | 1999

Purification and cloning of amyloid precursor protein beta-secretase from human brain.

Sukanto Sinha; John P. Anderson; Robin Barbour; Guriqbal S. Basi; Russell J. Caccavello; David P. Davis; Minhtam Doan; Harry F. Dovey; Normand Frigon; Jin Hong; Kirsten L. Jacobson-Croak; Nancy Jewett; Pamela S. Keim; Jeroen Knops; Ivan Lieberburg; Michael Power; Hua Tan; Gwen Tatsuno; Jay Tung; Dale Schenk; Peter Seubert; Susanna Suomensaari; Shuwen Wang; Donald A. Walker; Jun Zhao; Lisa McConlogue; Varghese John


Journal of Cell Biology | 1991

Overexpression of tau in a nonneuronal cell induces long cellular processes.

Jeroen Knops; Kenneth S. Kosik; G. Lee; J.D. Pardee; L. Cohen-Gould; Lisa McConlogue


Journal of Biological Chemistry | 1995

Cell-type and Amyloid Precursor Protein-type Specific Inhibition of Aβ Release by Bafilomycin A1, a Selective Inhibitor of Vacuolar ATPases

Jeroen Knops; Susanna Suomensaari; Michael K. Lee; Lisa McConlogue; Peter Seubert; Sukanto Sinha


Journal of Medicinal Chemistry | 2003

Design and Synthesis of Statine-Based Cell-Permeable Peptidomimetic Inhibitors of Human β-Secretase

Roy K. Hom; Larry Fang; Shumeye S. Mamo; Jay S. Tung; Ashley C. Guinn; Don Walker; David L. Davis; Andrea Gailunas; Eugene D. Thorsett; Sukanto Sinha; Jeroen Knops; Nancy Jewett; John P. Anderson; Varghese John


Journal of Biological Chemistry | 1992

Evidence for a nonsecretory, acidic degradation pathway for amyloid precursor protein in 293 cells. Identification of a novel, 22-kDa, beta-peptide-containing intermediate.

Jeroen Knops; Ivan Lieberburg; Sukanto Sinha


Archive | 1992

Beta-amyloid peptide production inhibitors and methods for their identification

Jeroen Knops; Sukanto Sinha


Journal of Biological Chemistry | 1991

Isolation of baculovirus-derived secreted and full-length beta-amyloid precursor protein.

Jeroen Knops; Kelly Johnson-Wood; Dale Schenk; Sukanto Sinha; Ivan Lieberburg; Lisa McConlogue


Journal of Biological Chemistry | 1991

Conversion of the Alzheimer's beta-amyloid precursor protein (APP) Kunitz domain into a potent human neutrophil elastase inhibitor.

Sukanto Sinha; Jeroen Knops; Fred Esch; Elizabeth D. Moyer; Tilman Oltersdorf


Archive | 1995

Use of inhibitors of adenosine triphosphatase for the manufacture of a medicament for the treatment of disorders anociated with beta-amyloid peptide

Jeroen Knops; Stephen Wyatt Queener; Sukanto Sinha


Neurobiology of Aging | 2000

Effects on APP processing and Aβ-production by CHAP-21/P519, a second membrane type aspartyl protease related to β-secretase

Guriqbal S. Basi; Normand Frigon; Tam Doan; Mike Power; Kirsten Jacobsen-Croak; John P. Anderson; Jeroen Knops; Ferdie Soriano

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Sukanto Sinha

University of California

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Kenneth S. Kosik

Brigham and Women's Hospital

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Susanna Suomensaari

University of Toledo Medical Center

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Varghese John

Buck Institute for Research on Aging

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Donald A. Walker

University of Alaska Fairbanks

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