Jin-Ming Yang

In(OTf)3 catalyzed C3-benzylation of indoles with benzyl alcohols in water

A novel C3-benzylation of indoles through C–O bond activation of benzyl alcohols catalyzed by In(OTf)3 in water has been developed. The reactions proceed smoothly in presence of In(OTf)3 as the catalyst without the use of any bases, ligands or other additives to perform the desired product in moderate to excellent yields.

Iodine-catalyzed Povarov reaction for synthesis of cyclobuta[c]quinoline derivatives

The iodine-catalyzed Povarov reaction of aromatic aldehydes, amines, and cyclobutanone in THF is described. The amines include naphthalen-2-amine and anthracen-2-amine. Cyclobuta[c]quinoline derivatives are obtained in high yields. This novel procedure has the advantages of mild reaction condition, high yields, and metal-free catalyst.Graphical Abstract

Microwave-Assisted Michael Addition of Diethyl Malonate with Ferrocenyl Substituted Chalcones Under Solvent-Free Conditions

Abstract The article describes an efficient, economical, and environmentally friendly approach for Michael addition of diethyl malonate to ferrocenyl substituted chalcones in the presence of microwave irradiation under solvent-free conditions, affording the corresponding Michael adducts in moderate to good yields of 53–94%.

Co-Catalyzed Synthesis of N-Sulfonylcarboxamides from Carboxylic Acids and Sulfonyl Azides

A Co-catalyzed effective synthesis of N-sulfonylcarboxamides from the reaction of carboxylic acids and organic azides in the presence of isocyanide has been developed. The protocol has the advantages of short time, low temperature, and being oxidant-free, which provides a new and simple approach for the synthesis of N-sulfonylcarboxamides in good to excellent yields with a broad substrate scope.

Efficient Synthesis of Ferrocenylcyclohexenone Under Solvent-Free Conditions

Abstract An efficient method for the synthesis of a series of ferrocenylcyclohexenones via tandem Michael–aldol reaction of ferrocenyl-substituted chalcones with dibenzyl ketone under solvent-free conditions is described. It was found that the factors including the electronic nature of chalcone, basicity of the base, reaction time, and temperature have effects on the formation of the ferrocenylcyclohexenones.