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John A. Ragan

California Institute of Technology

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Featured researches published by John A. Ragan.

Organic Process Research & Development | 2014

Commercial Route Research and Development for SGLT2 Inhibitor Candidate Ertugliflozin

Paul Bowles; Steven J. Brenek; Stephane Caron; Nga M. Do; Michele T. Drexler; Shengquan Duan; Pascal Dubé; Eric C. Hansen; Brian P. Jones; Kris Nicole Jones; Tomislav A. Ljubicic; Teresa W. Makowski; Jason Mustakis; Jade D. Nelson; Mark Olivier; Zhihui Peng; Hahdi H. Perfect; David William Place; John A. Ragan; John J. Salisbury; Corey L. Stanchina; Brian C. Vanderplas; Mark E. Webster; R. Matt Weekly

Organic Process Research & Development | 2003

Safe Execution of a Large-Scale Ozonolysis: Preparation of the Bisulfite Adduct of 2-Hydroxyindan-2-carboxaldehyde and Its Utility in a Reductive Amination

John A. Ragan; David J. am Ende; Steven J. Brenek; Shane Allen Eisenbeis; Robert A. Singer; Derek L. Tickner; John J. Teixeira; Brian C. Vanderplas; Neil Philip Weston

Organic Letters | 2006

Enantioselective Synthesis of Nicotinic Receptor Probe 7,8-Difluoro-1,2,3,4,5,6- hexahydro-1,5-methano-3-benzazocine

Crystal G. Bashore; Michael G. Vetelino; Michael C. Wirtz; Paige R. Brooks; Heather N. Frost; Ruth E. McDermott; David C. Whritenour; John A. Ragan; Jennifer L. Rutherford; Teresa W. Makowski; and Steven J. Brenek; Jotham Wadsworth Coe

Organic Syntheses | 2009

Large Scale, Green Synthesis of a Generation‐1 Melamine (Triazine) Dendrimer

Abdellatif Chouai; Vincent J. Venditto; Eric E. Simanek; Brian C. Vanderplas; John A. Ragan

Organic Process Research & Development | 2009

Development of a Practical and Efficient Synthesis of CP-945,598-01, a CB1 Antagonist for the Treatment of Obesity

John A. Ragan; Dennis E. Bourassa; Jon Blunt; Darragh Breen; Frank Robert Busch; Eric M. Cordi; David B. Damon; Nga M. Do; Alanya Engtrakul; Denis Lynch; Ruth E. McDermott; Joseph A. Mongillo; Maria M. O’Sullivan; Peter Robert Rose; Brian C. Vanderplas

Organic Syntheses | 2009

THE DIRECT ACYL-ALKYLATION OF ARYNES. PREPARATION OF METHYL 2-(2-ACETYLPHENYL)ACETATE.

David C. Ebner; Uttam K. Tambar; Brian M. Stoltz; Morten Storgaard; Nathan D. Ide; John A. Ragan; Jonathan A. Ellman

Organic Process Research & Development | 2003

Synthesis and purification of 6-ethoxy-4-oxo-1,4-dihydro-[1,5]naphthyridine-3-carboxylic acid benzylamide

Justin Beaudin; Dennis E. Bourassa; Paul Bowles; Michael J. Castaldi; Ronald J. Clay; Michel Couturier; Gregory L. Karrick; Teresa W. Makowski; Ruth E. McDermott; Clifford N. Meltz; Morgan Meltz; James Phillips; John A. Ragan; David H. Brown Ripin; Robert A. Singer; John L. Tucker; Lulin Wei

Organic Process Research & Development | 2014

Synthesis of Filibuvir. Part I. Diastereoselective Preparation of a β-Hydroxy Alkynyl Oxazolidinone and Conversion to a 6,6-Disubstituted 2H-Pyranone

Robert A. Singer; John A. Ragan; Paul Bowles; Esmort Chisowa; Brian G. Conway; Eric M. Cordi; Kyle R. Leeman; Leo J. Letendre; Janice E. Sieser; Gregory W. Sluggett; Corey L. Stanchina; Holly Strohmeyer; Jon Blunt; Stuart Taylor; Ciaran Byrne; Denis Lynch; Sandra Mullane; Maria M. O’Sullivan; Marcella Whelan

Organic Syntheses | 2009

SYNTHESIS OF 2-[3,3'-DI-(TERT-BUTOXYCARBONYL)-AMINODIPROPYLAMINE]-4,6,-DICHLORO-1,3,5-TRIAZINE AS A MONOMER AND 1,3,5-[TRIS-PIPERAZINE]-TRIAZINE AS A CORE FOR THE LARGE SCALE SYNTHESIS OF MELAMINE (TRIAZINE) DENDRIMERS.

Abdellatif Chouai; Vincent J. Venditto; Eric E. Simanek; Ruth E. McDermott; John A. Ragan

Organic Process Research & Development | 2014

Synthesis of Filibuvir. Part III. Development of a Process for the Reductive Coupling of an Aldehyde and a β-Keto-lactone

Nathan D. Ide; John A. Ragan; Gabriel Bellavance; Steve J. Brenek; Eric M. Cordi; Grace O. Jensen; Kris N. Jones; Danny Lafrance; Kyle R. Leeman; Leo J. Letendre; David William Place; Corey L. Stanchina; Gregory W. Sluggett; Holly Strohmeyer; Jon Blunt; Kevin Meldrum; Stuart Taylor; Ciaran Byrne; Denis Lynch; Sandra Mullane; Maria M. O’Sullivan; Marcella Whelan

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