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Ruth E. McDermott

Pfizer

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Featured researches published by Ruth E. McDermott.

Tetrahedron Letters | 1991

α-Azido acids in heterocyclic synthesis

Steven Wayne Goldstein; Ruth E. McDermott; Michael Raymond Groton Makowski; Cynthia Eller

Abstract 2-Aminobenzophenones and acetophenones were N-acylated with α-azido carboxylic acids to give the corresponding anilides. Reductive cyclization provided 3-substituted-2H-1,4-benzodiazepin-2-ones in good (46–99%) yields.

Journal of Medicinal Chemistry | 1992

Novel thiazolidine-2,4-diones as potent euglycemic agents

Bernard Hulin; David Alan Clark; Steven Wayne Goldstein; Ruth E. McDermott; Paul J. Dambek; Werner H. Kappeler; Charles H. Lamphere; Diana M. Lewis; James P. Rizzi

Synthesis | 2003

Alternative Biarylphosphines for Use in the Palladium-Catalyzed Amination of Aryl Halides

Robert A. Singer; Stephane Caron; Ruth E. McDermott; Patrice Arpin; Nga M. Do

Archive | 1995

Hypoglycemic hydroxyurea derivatives

Steven Wayne Goldstein; Ruth E. McDermott

Organic Letters | 2006

Enantioselective Synthesis of Nicotinic Receptor Probe 7,8-Difluoro-1,2,3,4,5,6- hexahydro-1,5-methano-3-benzazocine

Crystal G. Bashore; Michael G. Vetelino; Michael C. Wirtz; Paige R. Brooks; Heather N. Frost; Ruth E. McDermott; David C. Whritenour; John A. Ragan; Jennifer L. Rutherford; Teresa W. Makowski; and Steven J. Brenek; Jotham Wadsworth Coe

Organic Process Research & Development | 2001

Investigation of Methods for Seven-Membered Ring Synthesis: A Practical Synthesis of 4-Oxo-5,6,7,8-tetrahydro-4H-cyclohepta[b]furan-3-carboxylic Acid

John A. Ragan; Jerry Anthony Murry; Michael J. Castaldi; Alyson Kay Conrad; Brian P. Jones; Bryan Li; Teresa W. Makowski; Ruth E. McDermott; Barb J. Sitter; and Timothy D. White; Gregory R. Young

Organic Process Research & Development | 2009

Development of a Practical and Efficient Synthesis of CP-945,598-01, a CB1 Antagonist for the Treatment of Obesity

John A. Ragan; Dennis E. Bourassa; Jon Blunt; Darragh Breen; Frank Robert Busch; Eric M. Cordi; David B. Damon; Nga M. Do; Alanya Engtrakul; Denis Lynch; Ruth E. McDermott; Joseph A. Mongillo; Maria M. O’Sullivan; Peter Robert Rose; Brian C. Vanderplas

Organic Process Research & Development | 2003

Synthesis and purification of 6-ethoxy-4-oxo-1,4-dihydro-[1,5]naphthyridine-3-carboxylic acid benzylamide

Justin Beaudin; Dennis E. Bourassa; Paul Bowles; Michael J. Castaldi; Ronald J. Clay; Michel Couturier; Gregory L. Karrick; Teresa W. Makowski; Ruth E. McDermott; Clifford N. Meltz; Morgan Meltz; James Phillips; John A. Ragan; David H. Brown Ripin; Robert A. Singer; John L. Tucker; Lulin Wei

Organic Syntheses | 2009

SYNTHESIS OF 2-[3,3'-DI-(TERT-BUTOXYCARBONYL)-AMINODIPROPYLAMINE]-4,6,-DICHLORO-1,3,5-TRIAZINE AS A MONOMER AND 1,3,5-[TRIS-PIPERAZINE]-TRIAZINE AS A CORE FOR THE LARGE SCALE SYNTHESIS OF MELAMINE (TRIAZINE) DENDRIMERS.

Abdellatif Chouai; Vincent J. Venditto; Eric E. Simanek; Ruth E. McDermott; John A. Ragan

Synlett | 2000

Shock Sensitivity of a Vinamidinium Bis-Perchlorate Reagent and Demonstration of a Lower Energy Alternative

John A. Ragan; Ruth E. McDermott; Brian P. Jones; David J. am Ende; Pamela J. Clifford; Stanton McHardy; Steven D. Heck; Spiros Liras; Barb E. Segelstein

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John A. Ragan

Pfizer

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Nga M. Do

Pfizer

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Stephane Caron

Pfizer

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Steven Wayne Goldstein

Pfizer

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Teresa W. Makowski

Pfizer

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Brian P. Jones

Pfizer

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Michael J. Castaldi

Pfizer

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Robert A. Singer

Pfizer

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Alyson Kay Conrad

Pfizer

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Barb J. Sitter

Pfizer

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